Abstract: The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-? mediated conditions.
Type:
Application
Filed:
October 18, 2012
Publication date:
March 21, 2013
Applicants:
CEPHALON, INC., THE TRUSTEES OF THE UNIVERSITY OF PENNSYVANIA
Inventors:
The Trustees Of The University Of Pennsyvania, Cephalon, Inc.
Abstract: Devices, systems and methods for measuring infant feeding performance. The device includes a body portion, a pressure sensor and an integrated circuit. The body portion includes a first end for receiving a fluid, a second end mateable with a feeding nipple, and a conduit In fluid communication with the first and second ends. The pressure sensor is disposed in the body portion, is in contact with the fluid in the conduit, and generates a signal representing a pressure of the fluid passing through the conduit during a feeding session. The integrated circuit is disposed in the body portion and is electrically connected to the pressure sensor. The integrated circuit receives the pressure signal and determines a feeding factor over the feeding session indicative of the infant feeding performance.
Type:
Application
Filed:
April 27, 2009
Publication date:
April 14, 2011
Applicant:
The Trustees of the University of Pennsyvania
Inventors:
Jay N. Zemel, Barbara Medoff-Cooper, Joel Kaplan
Abstract: Hollow particles having a shell substantially composed of calcium-phosphate, methods for preparing the same, and methods of use are disclosed. The particles are obtained by differential immersion of silica-based, calcium and phosphate containing glass particles.
Type:
Grant
Filed:
May 9, 1996
Date of Patent:
July 9, 2002
Assignee:
The Trustees of the University of Pennsyvania
Inventors:
Shulamith Radin, Paul Ducheyne, Sylvie Falaize, Portonovo S. Ayyaswamy