Abstract: The present invention relates to compounds of the following general formula: (I) wherein R1 and R2 are fatty acyl groups, a process to extract them from Mycobacterium tuberculosis, and their use in the treatment or the prophylaxis of tuberculosis.
Type:
Grant
Filed:
April 9, 2004
Date of Patent:
April 10, 2012
Assignees:
Centre National de la Recherche Scientifique (C.N.R.S.), University Hospital of Basel, University of Erlangen
Inventors:
Germain Puzo, Martine Gilleron, Steffen Stenger, Gennaro De Libero
Abstract: Disclosed are methods of making BMP-2 microparticles and methods of using the microparticles. These microparticles are prepared, for example, by mixing a solution containing BMP-2 with a second solution whose ionic concentration and pH results in the precipitation of the BMP-2.
Type:
Grant
Filed:
February 10, 2003
Date of Patent:
March 1, 2011
Assignees:
University of Erlangen-Nurnberg, Wyeth Inc.
Inventors:
Susan J. Sofia, Daniel Schwartz, Wolfgang Friess
Abstract: A method teaches how to measure—even strongly curved—specular surfaces with an apparatus that measures a shape as well as local surface normals absolutely. This is achieved by the observation and evaluation of patterns that are reflected at the surface. The reflected patterns are observed from different directions. The evaluation is done by termination of those locations in space, where the surface normals that are observed from different directions, have at least deviations against each other.
Type:
Grant
Filed:
April 25, 2005
Date of Patent:
May 12, 2009
Assignees:
3D-Shape GmbH, The University of Erlangen
Inventors:
Gerd Haeusler, Markus Knauer, Ralf Lampalzer
Abstract: A method and kit for inhibiting the proliferation of cancer cells are disclosed, based on a combination of an apoptosis-inducing immunologic agent, and a sensitizing agent. When used in cancer therapy, the two agents in combination enhance the anti-cancer treatment efficacy obtained with the immunologic agent or the sensitizing agent alone, by a supraadditive amount.
Type:
Application
Filed:
April 26, 2007
Publication date:
October 30, 2008
Applicant:
Friedrich-Alexander University of Erlangen-Nuremberg
Inventors:
Georg H.M. Fey, Julia Stieglmaier, Michael Schwenkert, Michael Schwemmlein