Patents Assigned to The University of Hong Kong
  • Patent number: 11884009
    Abstract: The disclosure relates to a method or a platform for hydrogel-based 3D fabrication, wherein the hydrogel is patterned with a programmable femtosecond light sheet with a power density of 0.1 to 100 TW/cm2.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: January 30, 2024
    Assignees: The Chinese University of Hong Kong, Carnegie Mellon University
    Inventors: Shih-Chi Chen, Songyun Gu, Fei Han, Yongxin Zhao, Aleksandra Klimas
  • Patent number: 11888454
    Abstract: A blocking signal cancellation low noise amplifier system includes a first low noise amplifier, a second low noise amplifier, a blocking signal extraction and bias generation circuit, a bias switching circuit, and a bias switching signal generating circuit. The first low noise amplifier is used for dynamic input matching, and the first low noise amplifier receives an input signal and outputs it after amplifying. The blocking signal extraction and bias generation circuit is used to extract a blocking signal from the output signal of the first low noise amplifier, and output a DC voltage signal. The bias switching circuit is used to switch the first low noise amplifier between a blocking mode and a small signal mode. The bias switching signal generating circuit is used to compare the DC bias voltage signal VB2 with a preset reference voltage signal Vref.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: January 30, 2024
    Assignee: THE CHINESE UNIVERSITY OF HONG KONG, SHENZHEN
    Inventors: Liang Wu, Yifu Li, Xiaoping Wu, Shiyuan Zheng
  • Patent number: 11881605
    Abstract: Provided is an aqueous redox flow battery comprising a positive electrode, a negative electrode, a posolyte chamber containing a posolyte, a negolyte chamber containing a polyoxometalate as a negolyte, and a separator disposed between the posolyte chamber and the negolyte chamber, wherein the polyoxometalate has a conductivity of 65 mS cm?1 or more at ?20° C., and the aqueous redox flow battery has a power density of 250 mW cm?2 or more at ?20° C.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: January 23, 2024
    Assignee: The Chinese University of Hong Kong
    Inventors: Yi-Chun Lu, Fei Ai
  • Publication number: 20240021574
    Abstract: Disclosed is a method of bonding two copper structures involving compressing a first copper structure with a second copper structure under a stress from 0.1 MPa to 50 MPa and under a temperature of 250° C. or less so that a bonding surface of the first copper structure is bonded to the bonding surface of the second copper structure. At least one of the bonding surface of the first copper structure and the bonding surface of the second copper structure have a layer of nanograins of copper having an average grain size of 5 nm to 500 nm. The layer of the nanograins of copper having a thickness of 10 nm to 10 ?m.
    Type: Application
    Filed: June 16, 2023
    Publication date: January 18, 2024
    Applicant: The University of Hong Kong
    Inventors: Mingxin HUANG, Shien Ping FENG
  • Patent number: 11873551
    Abstract: An ultraflat and ultralow-friction metallic glass thin film is fabricated. The metallic glass thin film is a binary alloy, wherein a content of one metal element of the binary alloy is between 45 atomic % and 64 atomic %. The metallic glass thin film has an atomically smooth surface with a surface roughness Ra less than 0.1 nm and a total height of profile Rt less than 0.15 nm; the friction coefficient is below 1×10?2. Due to the metallic glass thin film being treated by ion bombardment, the metallic glass thin film is thermally ultrastable.
    Type: Grant
    Filed: March 27, 2022
    Date of Patent: January 16, 2024
    Assignee: City University of Hong Kong
    Inventors: Jian Lu, Jialun Gu, Yan Bao
  • Patent number: 11873527
    Abstract: Techniques are provided for detecting hematological disorders using cell-free DNA in a blood sample, e.g., using plasma or serum. For example, an assay can target one or more differentially-methylated regions specific to a particular hematological cell lineage (e.g., erythroblasts). A methylation level can be quantified from the assay to determine an amount of methylated or unmethylated DNA fragments in a cell-free mixture of the blood sample. The methylation level can be compared to one or more cutoff values, e.g., that correspond to a normal range for the particular hematological cell lineage as part of determining a level of a hematological disorder.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: January 16, 2024
    Assignee: The Chinese University of Hong Kong
    Inventors: Yuk-Ming Dennis Lo, Rossa Wai Kwun Chiu, Kwan Chee Chan, Kun Sun
  • Publication number: 20240011851
    Abstract: An optical soft skin system for multimodal sensing comprising: a flexible waveguide substrate (10) being able to change its light wave propagation when encountering different deformation patterns; at least one light source (12) located within the waveguide substrate (10) arranged so as to transmit light into the waveguide substrate (10); at least one light receptor (14) located within the waveguide substrate (10) to receive light that has passed through the waveguide substrate (10) and to provide a dataset of the properties of the received light; and a processor (20) for decoding the dataset into at least one of strain and displacement through a computational model to determine a sensing modality of the waveguide substrate (10).
    Type: Application
    Filed: November 3, 2021
    Publication date: January 11, 2024
    Applicant: THE UNIVERSITY OF HONG KONG
    Inventors: Ka Wai Kwok, Kui Wang, Chi Hin Mak, Zhi Yu Liu, Di-Lang Ho
  • Patent number: 11866815
    Abstract: A method for preparing a high entropy alloy (HEA) structure includes the steps of: preparing an alloy by arc melting raw materials comprising five or more elements; drop casting the melted alloy into a cooled mold to form a bulk alloy; applying an external force against the bulk alloy to reshape the bulk alloy; and heat-treating the reshaped bulk alloy, wherein the bulk alloy is reshaped and/or heat-treated for manipulating the distribution of the microstructure therein. The present invention also relates to a high entropy alloy structure prepared by the method.
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: January 9, 2024
    Assignee: City University of Hong Kong
    Inventors: Yong Yang, Quanfeng He, Zhaoyi Ding
  • Patent number: 11858200
    Abstract: The present invention provides a method of in situ 4D printing of high-temperature materials including 3D printing a structure of an ink including a precursor. The structure is treated with controlled high energy flow to create a portion which has a different coefficient of thermal expansion/thermal shrinkage ratio. The structure is heated and the difference in the coefficient of thermal expansion creates an interface stress to cause a selected level of deformation. Alternatively, two structures with different coefficients of expansion/thermal shrinkage ratio may be printed. Thermal treatment of the two structures creates an interface stress to cause a selected level of deformation.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: January 2, 2024
    Assignee: City University of Hong Kong
    Inventors: Jian Lu, Guo Liu
  • Patent number: 11862792
    Abstract: This invention relates to a zinc powder electrode formed on a MXene framework. The zinc powder anode formed on an MXene framework, referred to as an MXene@Zn electrode can act as an anode and/or cathode for an electrochemical cell or battery. As such, the present invention further relates to an electrode comprising MXene@Zn and a battery comprising such an electrode.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: January 2, 2024
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Chunyi Zhi, Xinliang Li, Zhaodong Huang, Qi Yang
  • Publication number: 20230417307
    Abstract: A muscle-like actuator comprises a motor with a rotatable drive shaft and a string with a shear thickening fluid (STF) embedded therein. One end of the string is attached to the drive shaft and the other end is connected to a load to form a twisted string actuator (TSA). By controlling the speed and current of the motor, the characteristics of the actuator can be changed. Multiple strings may be located in a flexible soft tube to improve the mechanical properties of the actuator.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 28, 2023
    Applicant: The University of Hong Kong
    Inventors: Ning XI, Qingqing ZHANG, Yafei ZHAO
  • Publication number: 20230420247
    Abstract: A thin film (Ga 0.5%, Cu 8%) co-doped ZnO with high dielectric constant and high optical transmittance in the visible light range is formed via a pulse laser deposition method. The steps of the method involve installing a sapphire based substrate mounted on a sample holder into a pulse laser deposition chamber; and installing a ZnO ceramic target containing designed Ga and Cu concentrations in the chamber. Then the chamber is evacuated until the pressure achieves 5e-4 Pa., at which point the substrate is heated to about 600 degrees C. Next oxygen gas is introduced into the chamber and adjusted to a pressure of about 5 Pa. The rotation speed of the substrate holder and target holder are adjusted to about 10 r/min. Finally, the laser beam is applied to the target to ablate it sufficiently to generate a plasma of ionized atoms that are deposited on the substrate to form the film with the same composition same as the target.
    Type: Application
    Filed: January 6, 2022
    Publication date: December 28, 2023
    Applicant: THE UNIVERSITY OF HONG KONG
    Inventors: Dong HUANG, Chi Chung Francis LING
  • Patent number: 11853387
    Abstract: A data sparse projection method, includes: randomly initializing a high-dimensional sparse two-dimensional matrix (S1); fixing the high-dimensional sparse two-dimensional matrix, and calculating an optimal output variable by using the high-dimensional sparse two-dimensional matrix (S2); fixing the optimal output variable, and calculating an optimal high-dimensional sparse two-dimensional matrix by using the optimal output variable (S3); and cyclically fixing the high-dimensional sparse two-dimensional matrix and the output variable until the optimal output variable is no longer increased when the high-dimensional sparse two-dimensional matrix is fixed (S4).
    Type: Grant
    Filed: April 12, 2023
    Date of Patent: December 26, 2023
    Assignee: THE CHINESE UNIVERSITY OF HONG KONG, SHENZHEN
    Inventors: Chonglin Gu, Changyi Ma, Wenye Li, Shuguang Cui
  • Patent number: 11851675
    Abstract: The subject invention pertains to methods and devices for generating mature oocytes from immature oocytes and improving oocyte quality for improved success of assistant reproductive technology (ART). The methods include the use of tunneling nanotube-forming cells and oocytes, wherein the tunneling nanotube-forming cells transfer autologous genomic materials, biomolecules and cellular components to the oocytes. The devices of the invention include microfluidic device to improve the efficiency of the transfer of biomolecules and cellular components between tunneling nanotube-forming cells and oocytes.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: December 26, 2023
    Assignee: The Chinese University of Hong Kong
    Inventors: Tin Lap Lee, Tin Chiu Li, Yiu Leung Chan, Wing Tung Lee, Kin Wing Judy Ng, Ting Hei Thomas Chan
  • Patent number: 11851401
    Abstract: The present disclosure provides a method of preparing unsaturated hydrocarbons by black body photocatalytic (thermal radiative catalytic) conversion of saturated hydrocarbons. In this method, a saturated hydrocarbon reaction gas is introduced into a reaction furnace, and the saturated hydrocarbon is catalyzed to convert under heating and illumination conditions to prepare the unsaturated hydrocarbons. The photocatalysis is combined to the conventional thermal catalysis to improve the catalytic performance, accelerate the reaction speed, increase the conversion rate, and/or improve the selectivity of the catalytic reaction.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: December 26, 2023
    Assignees: THE CHINESE UNIVERSITY OF HONG KONG, SHENZHEN, UNIVERSITY OF TORONTO
    Inventors: Lu Wang, Geoffrey Alan Ozin, Zeshu Zhang, Xue Ding, Zhigang Zou
  • Patent number: 11848499
    Abstract: An on-chip antenna comprising an electrically insulating substrate having first and second faces; a metal layer arranged on the second face; and, a dipole antenna structure arranged on the first face, the dipole antenna structure comprising a dipole antenna and a feed structure connected to the dipole antenna; the on-chip antenna being configured such that when the feed structure is fed with an electrical signal it operates simultaneously in (i) at least one dielectric resonator mode to function as a dielectric resonance antenna, and (ii) at least one dipole mode to function as a cavity backed dipole antenna.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: December 19, 2023
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Chi Hou Chan, Shang Cheng Kong, Kam Man Shum
  • Patent number: 11845821
    Abstract: The present disclosure provides a humidity-stiffening polymer material, and a preparation method therefor and a use thereof. The humidity-stiffening polymer material includes the following raw materials: a monomer, an ionic liquid, a salt, a cross-linking agent and an initiator, wherein the monomer includes benzyl methacrylate, the ionic liquid includes an imidazole-based ionic liquid, and the salt includes a hygroscopic salt. The method for preparing the humidity-stiffening polymer material includes: mixing the raw materials to obtain a precursor liquid, performing reaction on the mixture after degassing, and drying the mixture to obtain the humidity-stiffening polymer material. The humidity-stiffening polymer material is applied to actuators, soft robots and wearable biomedical devices based on bionic design.
    Type: Grant
    Filed: November 2, 2022
    Date of Patent: December 19, 2023
    Assignee: The Chinese University of Hong Kong, Shenzhen
    Inventors: Shiping Zhu, Xiaoqing Ming, Le Yao, Qi Zhang
  • Patent number: 11839428
    Abstract: Disclosed is a method for analyzing a distribution of retinal lesions in a mouse model, including: scanning a mouse posterior polar fundus based on optical coherence tomography (OCT), and acquiring lesion images of the mouse posterior polar fundus; acquiring lesion distribution coordinates based on the lesion images of the mouse posterior polar fundus; constructing a coordinate map of a lesion distribution rule based on the lesion distribution coordinates; and acquiring lesion distribution in quadrants based on the coordinate map of the lesion distribution rule, and calculating and counting a number of lesions in each quadrant.
    Type: Grant
    Filed: May 1, 2023
    Date of Patent: December 12, 2023
    Assignee: JOINT SHANTOU INTERNATIONAL EYE CENTER OF SHANTOU UNIVERSITY AND THE CHINESE UNIVERSITY OF HONG KONG
    Inventors: Haoyu Chen, Xiaoting Mai, Shaofen Huang, Meiqin Zhang
  • Patent number: 11839998
    Abstract: Three-dimensional (3D) hierarchical morphologies widely exist in natural and biomimetic materials, which impart preferential functions including liquid and mass transport, energy conversion, and signal transmission for various applications. While notable progress has been made in the design and manufacturing of various hierarchical materials, the state-of-the-art approaches suffer from limited materials selection, high costs, as well as low processing throughput. Herein, by harnessing the configurable elastic crack engineering-controlled formation and configuration of cracks in elastic materials, an effect normally avoided in various industrial processes, the present invention provides a facile and powerful technique to enable the faithful transfer of arbitrary hierarchical structures with broad material compatibility and structural and functional integrity.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: December 12, 2023
    Assignees: Hong Kong Baptist University, The Hong Kong University of Science and Technology, City University of Hong Kong
    Inventors: Kangning Ren, Hongkai Wu, Zuankai Wang, Shuhuai Yao, Beng Ong, Wanbo Li, Zeyu Li, Han Sun, Chiu Wing Chan
  • Patent number: 11842794
    Abstract: Systems and methods for variant calling in single molecule sequencing from a genomic dataset using a convolutional deep neural network. The method includes: transforming properties of each of the variants into a multi-dimensional tensor; passing the multi-dimensional tensors through a trained convolutional deep neural network to predict categorical output variables, the convolutional deep neural network minimizing a cost function iterated over each variant, the convolutional deep neural network trained using a training genomic dataset including previously identified variants, the convolutional neural network including: a plurality of pooled convolutional layers and at least two fully-connected layers connected sequentially after the last of the pooled convolutional layers, the at least two fully-connected layers comprising a second fully-connected layer connected sequentially after a first fully-connected layer; and outputting the predicted categorical output variables.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: December 12, 2023
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Ruibang Luo, Tak-Wah Lam, Chi-Man Liu