Patents Assigned to The University of Mississippi
  • Patent number: 7894305
    Abstract: A method of detecting a human, that includes (a) measuring the ultrasonic signal emitted from human footsteps; (b) measuring the human body motion Doppler signature; reviewing the measurements of steps (a) and (b); and (d) determining the presence of a human.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: February 22, 2011
    Assignee: University of Mississippi
    Inventors: James M. Sabatier, Alexander E. Ekimov, Carl K. Frederickson
  • Patent number: 7867981
    Abstract: A method for treating fungal infections in a mammal that includes administering a therapeutically effective amount of a composition comprising substantially pure amphotericin B and a pharmaceutically acceptable carrier. Amphotericin BHP is associated with decreased toxicity in mammals and cells measured by cell viability and expression of cytokine markers. Thus, this method allows for reduced adverse reactions when using amphotericin B products.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: January 11, 2011
    Assignee: University of Mississippi
    Inventors: John D. Cleary, Stanley W. Chapman, Robert E. Kramer
  • Publication number: 20100329978
    Abstract: Compounds having the general formula II, III, or IV wherein R1 can be a radical of an optionally substituted C-4 to C-7 N-containing heterocycle or a radical of an optionally substituted cyclic or acyclic tertiary amine or isoindoline-1,3-dione: R2,3,4,5,6 can each independently be any one or combinations of the following moieties, cyano, nitro, acyl, alkyl, amido, azido, isothiocyanate, isocyanate, optionally substituted anilino, halogens, ethers, sulfonamides, thioacyl, nitro, aromatic, heterocyclic, olefinic, acetylene, deuterium, or tritium; Y can be either CH, CH2, O, S, OCH2, N—R, N—Ar, C—R, C—Ar; Z can be either H, O, S, S—R or NR.
    Type: Application
    Filed: May 21, 2010
    Publication date: December 30, 2010
    Applicants: University of Mississippi, I'Universite catholique de Louvain
    Inventors: Christopher R. McCurdy, Christophe Mesangeau, Rae Reiko Matsumoto, Jacques Henri Poupaert, Bonnie Ann Avery, Ahmed Hassan Amin Abdelazeem
  • Patent number: 7846452
    Abstract: Immunostimulatory compounds can be extracted from microalgae or algae using various procedures. The resulting preparations exhibit extremely potent immunostimulatory activity. The extraction of these immunostimulatory agents is dependent on the solvent used and the extraction temperature. These preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function.
    Type: Grant
    Filed: July 28, 2005
    Date of Patent: December 7, 2010
    Assignee: The University of Mississippi
    Inventors: David Pasco, Nirmal Pugh
  • Publication number: 20100255130
    Abstract: Methods for providing skin enhancement and pain relief to an individual in need of treatment by administering to such an individual an effective amount of an immunostimulatory Aloe vera derived composition. Oral and topical methods and compositions are provided. Aloe vera derived immunostimulatory compositions and methods of producing such compositions are provided.
    Type: Application
    Filed: May 9, 2008
    Publication date: October 7, 2010
    Applicants: ALOEBIOTICS RESEARCH LABS, INC., UNIVERSITY OF MISSISSIPPI
    Inventors: Denise DeBaun, David Stanley Pasco, Nirmal Derek Ceri Pugh, Alex Pashkowsky, Alvin Needleman
  • Publication number: 20100234311
    Abstract: This present provides kaempferol-3-(2-E,3-Z-di-p-coumaroyl)-rhamnoside, kaempferol-3-(2-Z-3-E-di-p-coumaroyl)-rhamnoside, and kaempferol-3-(2,3-di-Z-p-coumaroyl)-rhamnoside compounds useful as a new class of anti-bacterial agents. These compounds are extracted from Platanus occidentalis. These compounds were found to exhibit anti-bacterial activity against methicillin resistant Staphylococcus aureus (MRSA).
    Type: Application
    Filed: March 16, 2010
    Publication date: September 16, 2010
    Applicant: The University of Mississippi
    Inventors: Mark T. Hamann, Mohamed Ali
  • Patent number: 7767655
    Abstract: A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated from Aloe vera. The polysaccharide fraction has an apparent molecular weight above 2 million daltons. Its major glycosyl components are glucose, galactose, mannose and arabinose. The invention further includes pharmaceutical compositions containing the instant polysaccharide fraction, optionally in combination with acceptable pharmaceutical carriers and/or excipients. These pharmaceutical compositions may be used to provide immunostimulation to an individual in need of such treatment by administering to such an individual an effective amount of the composition. The polysaccharide fraction is also useful as a component of dietary supplements and as a standardization component of commercial Aloe products.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: August 3, 2010
    Assignee: University of Mississippi
    Inventors: David Stanley Pasco, Nirmal Derek Pugh, Mahmoud Elsohly, Samir Ross
  • Patent number: 7687538
    Abstract: Compounds and compositions that are salvinorin A and salvinorin B derivatives that demonstrate selectivity and/or potency for the k-opioid receptor (KOR), allowing for their use as medicines, as well as chemical probes (both radiolabeled and cold) for fields utilizing the techniques of radiolabeled binding assays.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: March 30, 2010
    Assignees: University of Mississippi, Case Western Reserve University
    Inventors: Jordan Zjawiony, Hesham Fahmy, David Jeremy Stewart, Bryan Roth
  • Patent number: 7688675
    Abstract: A system for assessing underwater biomass that comprises a frame that can float and hold the system on a body of water; a transducer that emits and receives wave signals; a motor box, that positions the transducer below a water line; a control unit to allow a user to operate the system and view results obtained from the system; an electronics housing that receives a CPU board that communicates with and relays information to and from, the control unit; and a communication device to facilitate communication between the control unit and the CPU board.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: March 30, 2010
    Assignee: University of Mississippi
    Inventors: James P. Chambers, Henry E. Bass, Kenneth E. Gilbert, Daniel E. Kleinert, Jr.
  • Publication number: 20100003275
    Abstract: Potent immunostimulatory lipoproteins have been identified within the following microalgae and extracts thereof: Spirulina species, Chlorella species, Haematococcus pluvialis and Aphanizomenon flos-aquae. This lipoprotein component can be extracted from the microalgae or microalgae spent material using various procedures. The resulting preparations exhibit extremely potent immunostimulatory activity. These preparations are potentially useful as a botanical or pharmaceutical preparation to improve immune function. Methods are also disclosed for the chemical and bioactivity based standardization of immunostimulatory microalgae extracts and the raw material.
    Type: Application
    Filed: September 10, 2007
    Publication date: January 7, 2010
    Applicant: THE UNIVERSITY OF MISSISSIPPI
    Inventors: David Stanley Pasco, Nirmal Derek Ceri Pugh
  • Publication number: 20090281634
    Abstract: A prosthetic device for the intestine is disclosed that bypasses an enterocutaneous fistula so that the intestinal tract can properly function without bowel contents leaking onto the skin. The prosthetic device includes means to securely connect and seal it to the intestine, means to push bowel contents through it, and means to prevent the backflow of bowel contents through the digestive tract.
    Type: Application
    Filed: May 8, 2009
    Publication date: November 12, 2009
    Applicant: The University of Mississippi Medical Center Research Development Foundation
    Inventors: Thomas L. Abell, Christopher J. Lahr, Derek F. Lahr
  • Publication number: 20090049915
    Abstract: A method and system for detecting the presence of subterranean termites, involving use of a thermal imaging camera to scan the structure before installation of an acoustic sensor in order to quickly locate potential areas of subterranean termite infestation, and an acoustic sensor in the form of an accelerometer or the disclosed innovative acoustic sensors having a bandwidth of at least 100 Hz to 15 kHz to detect noises made by the subterranean termites. Information collected by the acoustic sensor may be transmitted to a portable mini-computer (pocket PC) for confirmation and to a central operations center for inclusion in a comprehensive database of termite data and information.
    Type: Application
    Filed: August 15, 2007
    Publication date: February 26, 2009
    Applicant: The University of Mississippi
    Inventor: Peng Lee
  • Patent number: 7475550
    Abstract: A method and device to reduce the noise produced by jet aircraft engines and/or other supersonic nozzles involves the use of corrugated engine seals (30) for the secondary internal divergent flaps (14) of the nozzle (10). Such corrugated seals (30) serve not only to eliminate shock-generated noise, but also generate a counter-rotating vorticity to force low speed mixing of surrounding ambient air with the high-speed jet exhaust. Lower exhaust velocities, combined with reduced levels of the turbulent Reynolds shear stress, lead to reduction of turbulence-generated noise, including Mach wave emission.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: January 13, 2009
    Assignee: University of Mississippi
    Inventor: John M. Seiner
  • Publication number: 20090000958
    Abstract: An anti-corrosive composition, comprising a combination of at least two of the following materials: vanadates, molybdates, tungstates, silicates, phosphates, borates. Ce cations, Y cations, La cations, Eu cations, Gd cations, Nd cations, and reaction products thereof.
    Type: Application
    Filed: March 1, 2006
    Publication date: January 1, 2009
    Applicant: UNIVERSITY OF MISSISSIPPI MEDICAL CENTER
    Inventors: S. Ray Tayler, Brian D. Chambers
  • Patent number: 7470703
    Abstract: Yohimbine derivatives are disclosed having modification of the C-16 carboxyl group to include a sidechain and where the resulting derivative does not possess a second yohimbine pharmacophore (i.e., the compound is not a yohimbine dimer). The yohimbine derivatives of the present invention are preferably characterized by selective activity as ?2c-AR antagonists. Use of the compounds, or pharmaceutical composition containing them, for treating or preventing an ?2c adrenergic receptor mediated condition or disorder, and for antagonizing activity of an ?2c adrenergic receptor are also disclosed.
    Type: Grant
    Filed: August 23, 2005
    Date of Patent: December 30, 2008
    Assignees: The University of Tennessee Research Foundation, The University of Mississippi
    Inventors: Duane D. Miller, Bob M. Moore, II, Suni Mustafa, Dennis R. Feller, Supriya A. Bavadekar
  • Patent number: 7468445
    Abstract: The present invention provides a method of preventing or treating one or more of the following medical conditions, or treating symptoms of one or more of the following medical conditions: amebic infections, giardiasis, estrogen deficient states, osteoporosis, cardiovascular heart disease, high cholesterol levels, hyperlipidemia, cancer by administering to a subject having, or predisposed to, one or more of the conditions, a therapeutically effective amount of a compound of the present invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: December 23, 2008
    Assignee: University of Mississippi
    Inventors: Mitchell Avery, Larry A. Walker, Nakul Telang
  • Publication number: 20080275106
    Abstract: This invention comprises compositions containing dihydroartemisinin- and dihydroartemisitene-dimers with activity as anticancer or anticancer metastasis agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer or prevention of cancer metastasis, and protozoal infections, including malaria, or leishmaniasis. The compounds of this invention represent a potential new class of anti-tumor or anti-metastasis agents, one that has shown promising activity against solid tumors.
    Type: Application
    Filed: June 21, 2005
    Publication date: November 6, 2008
    Applicant: THE UNIVERSITY OF MISSISSIPPI
    Inventors: Mahmoud A. Elsohly, Waseem Gul
  • Patent number: 7436330
    Abstract: A method is provided for compressing data from a stream of values using one or many distinct memory addresses as workspace, each memo address containing one or many values. The method works by reading two contiguous data values, of length K and N bits, from the stream, as a memory address reference (MAR) and a symbol, respectively. If the symbol does not match any of the values in the memory address pointed by MAR, the symbol replaces one of those values, and a MISS code, followed by the symbol, is appended to the compressed stream. Otherwise, a HIT code is added appended directly to the compressed stream, the code representing the location, of the matched value in the memory address. Advantageously, the workspace behaves analogous to a cache memory used in computer architecture, allowing it to be implemented using content addressable memory or associative arrays in hardware or software implementations, respectively.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: October 14, 2008
    Assignee: The University of Mississippi
    Inventor: Luis Paris
  • Patent number: 7434990
    Abstract: A method for confirming the presence of termites in a structure, involving a preliminary infrared scan of a structure and confirmation of termite infestation with at least one detector in order to quickly locate potential areas of termite infestation.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: October 14, 2008
    Assignee: University of Mississippi
    Inventor: Peng Lee
  • Patent number: 7429928
    Abstract: A method and system for detecting the presence of subterranean termites, involving use of a thermal imaging camera to scan the structure before installation of an acoustic sensor in order to quickly locate potential areas of subterranean termite infestation, and an acoustic sensor in the form of an accelerometer or the disclosed innovative acoustic sensors having a bandwidth of at least 100 Hz to 15 kHz to detect noises made by the subterranean termites. Information collected by the acoustic sensor may be transmitted to a portable mini-computer (pocket PC) for confirmation and to a central operations center for inclusion in a comprehensive database of termite data and information.
    Type: Grant
    Filed: September 26, 2007
    Date of Patent: September 30, 2008
    Assignee: University of Mississippi
    Inventor: Peng Lee