Abstract: The present disclosure provides systems, methods, and computer-readable media for managing graphics processing unit (GPU) allocation for a virtual machine (VM). A first GPU driver, associated with a first GPU, is offloaded from an operating system (OS) of the VM. Then, the first GPU is deallocated from the VM. A second GPU is allocated to the VM, and a second GPU driver, associated with the second GPU, is loaded in the OS of the VM. To restore a GPU context from the first GPU within the second GPU, a GPU command log from the first GPU is replayed to the second GPU.
Type:
Grant
Filed:
September 5, 2016
Date of Patent:
May 3, 2022
Assignees:
Huawei Technologies Co., Ltd., The Governing Council of the University of Toronto
Inventors:
Eyal de Lara, Daniel Kats, Graham Allsop, Weidong Han, Feng Xie
Abstract: Herein is described the design and synthesis of resorcylate aminopyrazole compounds. These compounds show broad, potent and fungal-selective Hsp90 inhibitory activity. These compounds also find use in treating Hsp90 related diseases.
Type:
Grant
Filed:
May 6, 2020
Date of Patent:
April 26, 2022
Assignees:
TRUSTEES OF BOSTON UNIVERSITY, The Governing Council of the University of Toronto
Inventors:
Lauren Elaine Brown, David S Huang, Leah E. Cowen, Luke Whitesell, Paul Marcyk
Abstract: A semiconductor nanocrystal particle represented by Chemical Formula 1 and having a full width at half maximum (FWHM) of less than or equal to about 30 nanometers (nm) in the emission wavelength spectrum is provided: AxA?(3+??x)D(2+?)E(9+?).??Chemical Formula 1 In Chemical Formula 1, A is a first metal including Rb, Cs, or a combination thereof, A? is an organic substance derived from an ammonium salt, an organic material derived from an organic ligand, or an organic material including a combination thereof, D is a second metal including Sb, Bi, or a combination thereof E is Cl, Br, I, or a combination thereof, 1<x?3, ?1<?<1, 3+??x>0, ?1<?<1, and ?1<?<1.
Type:
Grant
Filed:
August 6, 2020
Date of Patent:
April 26, 2022
Assignees:
SAMSUNG ELECTRONICS CO., LTD., THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Jihyun Min, Eun Joo Jang, Edward H. Sargent, Hyo Sook Jang, Makhsud I. Saidaminov, Sjoerd Hoogland, Ankit Jain, Andrew Johnston, Oleksandr Voznyy
Abstract: Disclosed herein are perovskite based optoelectronic devices made entirely via solution-processing at low temperatures (<150° C.) which provide for simple manufacturing, compatibility with flexible substrates, and perovskite-based tandem devices. These perovskite based optoelectronic devices are produced using an electron transport layer on which the perovskite layer is formed which is passivated using a ligand selected to reduce electron-hole recombination at the interface between the electron transport layer and the perovskite layer.
Type:
Grant
Filed:
January 30, 2018
Date of Patent:
April 19, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Abstract: A miR-1983 inhibitor comprising an anti-miR-1983 oligonucleotide that is complementary to at least part of CTCACCTGGAGCATGTTTTCT (SEQ ID NO: 1), the part comprising at least nucleotides 2 to 8 of CTCACCTGGAGCATGTTTTCT (SEQ ID NO: 1).
Type:
Grant
Filed:
August 24, 2018
Date of Patent:
April 12, 2022
Assignee:
The Governing Council of the University of Toronto
Abstract: The disclosure concerns a class of hemoglobin based oxygen carriers (HBOCs) comprising a first hemoglobin protein cross-linked by a chemical reaction that is followed by a strain-promoted alkyne-azide cycloaddition (SPAAC) reaction or by a strain-promoted alkyne-nitrone cycloaddition (SPANC) in the absence of added copper salts to a second modified cross-linked hemoglobin protein. The resulting construct is an HBOC that is capable of binding oxygen and releasing same in a useful manner upon addition in an appropriate solution to the circulatory system of a patient. The disclosure also concerns a method of production of the HBOC where a first and second hemoglobin protein are produced by covalently linking hemoglobin to an angle strained cycloalkyne moiety.
Type:
Grant
Filed:
September 21, 2017
Date of Patent:
April 12, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Ronald Henry Kluger, Serena Singh, Ina Dubinsky-Davidchik
Abstract: Disclosed herein is a surfactant additive, ethylenediamine tetrakis(ethoxylate-block-propoxylate) tetrol with 16 ethylene oxide repeat units and 18 propylene oxide repeat units (known by its trade name as Tetronic 90R4) used as a droplet-additive, or to coat DMF driving electrode surfaces which dramatically improves the capability to work with high-protein-content liquids (e.g., whole blood) on digital microfluidic chips. This surfactant prevents protein adsorption and fouling of DMF electrode surfaces to an extent that was heretofore impossible. Specifically, this surfactant allows for the manipulation of droplets of undiluted whole blood for >1 hour per electrode (>1 50 times better than what is possible for any known additive). This improvement in handling high protein content media will revolutionize blood-based diagnostics on digital microfluidic platforms.
Type:
Grant
Filed:
March 31, 2017
Date of Patent:
April 5, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Ryan Fobel, Alphonsus Hon-Chung Ng, Aaron Ray Wheeler, Man Ho Stephen Ho
Abstract: A three-dimensional (3D) untethered mobile actuator having the following parts: (a) a substrate having two or more magnetized panels, and (b) a frame that connects the magnetized panels, the magnetized panels being made of a polymer with embedded permanent magnetic particles, each magnetized panel of the 3D untethered mobile actuator having a magnetic moment in a different direction than a next neighboring panel, and the 3D untethered mobile actuator having a structural configuration that changes between a substantially flat structural configuration in the absence of a magnetic field, and an actuated structural configuration when under influence of a magnetic field. Methods of manufacturing and using the 3D mobile actuator and a system that includes the 3D mobile actuator are provided.
Type:
Grant
Filed:
June 8, 2018
Date of Patent:
March 29, 2022
Assignee:
The Governing Council of the University of Toronto
Abstract: A module for interconnecting a pair of DC sources or a pair of DC loads into a DC bus includes: a first port for each source or load; a switching cell for each first port, each cell having a pair of terminals and a switching node; a second port operatively connected to the DC bus and having a pair of terminals, one of the pair of terminals of the second port being connected to one of the terminals of one of the cells and the other of the pair of terminals of the second port being connected to one of the terminals of the other of the cells; and a filter inductor connected between the switching nodes of the cells. Systems including the module and methods utilizing the system are also disclosed.
Type:
Grant
Filed:
August 15, 2020
Date of Patent:
March 29, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Peter Waldemar Lehn, Mike Kavian Ranjram, Sebastian Rivera Iunnissi, Yuanzheng Han
Abstract: Described herein are systems and methods for building information modeling. An embodiment of the method includes: receiving a BIM; and transforming the BIM to flatten solid-volume geometry for space bounding elements into thin-walled boundaries of the thermal zones by: determining wall volumes from the BIM; collapsing the wall volumes to provide single surface walls; determining wall center surfaces and end points from the single surface walls; aligning, and trimming or extending, the single surface walls using the wall end points to create closed spaces; connecting the closed spaces vertically to generate a single water tight volume for the closed spaces; and creating interfaces between the single water tight volume for the closed spaces to generate thermal zones.
Type:
Grant
Filed:
June 25, 2018
Date of Patent:
March 8, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Tamar El-Diraby, Emmanouil Papangelis, Thomas Krijnen
Abstract: The invention relates to a catalyst system for electrocatalyzing conversion of CO2 into multi-carbon hydrocarbons and/or alcohols, and to the method to produce it. The catalyst comprises a core-shell structure comprising a core that is composed of metal sulphide and a shell that is composed of a metal with vacancies.
Type:
Grant
Filed:
May 8, 2019
Date of Patent:
March 8, 2022
Assignees:
TOTAL SE, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Edward Sargent, Tao-Tao Zhuang, Zhi-Qin Liang, Alexander Ip
Abstract: Embodiments of the present disclosure relate to generating explanation maps for explaining convolutional neural networks through attribution-based input sampling and block-wise feature aggregation. An example of a disclosed method for generating an explanation map for a convolutional neural network (CNN) includes obtaining an input image resulting in an output determination of the CNN, selecting a plurality of feature maps extracted from a plurality of pooling layers of the CNN, generating a plurality of attribution masks based on the plurality of feature maps, applying the generated attribution masks to the input image to obtain a plurality of visualization maps, and generating an explanation map of the output determination of the CNN based on the plurality of visualization maps.
Type:
Application
Filed:
August 18, 2021
Publication date:
February 24, 2022
Applicants:
LG ELECTRONICS INC., The Governing Council of the University of Toronto
Inventors:
Jongseong Jang, Hyunwoo Kim, YeonJeong Jeong, SangMin Lee, Sam Sattarzadeh, Mahesh Sudhakar, Shervin Mehryar, Anthony Lem, Konstantinos Plataniotis
Abstract: An automated multiplex detector system includes: (a) a nucleic acid amplification compartment for amplifying nucleic acid of one or more targets in a sample, and (b) an analysis compartment in fluid communication with the amplification compartment, the analysis compartment housing a nanoparticle-based multiplex detector capable of using the amplified nucleic acid of the amplification compartment and producing a signal that correlates with the presence of the one or more targets in the sample.
Type:
Grant
Filed:
June 17, 2016
Date of Patent:
February 15, 2022
Assignee:
The Governing Council of the University of Toronto
Inventors:
Warren C. W. Chan, Jisung Kim, Kyrylo Zagorovsky
Abstract: A method for dissociating cell aggregates in an agitated reactor. The method comprises providing a cell culture comprising cell aggregates in the agitated reactor, contacting the cell aggregates with a dissociation reagent, generating a dissociation force in the agitated reactor and exposing the contacted cell aggregates to the generated dissociation force under conditions sufficient to dissociate the contacted cell aggregates. The method may be used in a process for passaging cells and/or generating dissociated differentiated cells from stem and/or progenitor cells.
Type:
Grant
Filed:
January 25, 2017
Date of Patent:
February 8, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Abstract: The present disclosure provides substantially homogeneously dispersed multimetal oxy-hydroxide catalyst comprising at least two metals, at least one metal being a transition metal, and at least a second metal which is structurally dissimilar to at least one metal, such that the multimetal oxy-hydroxide is characterized by being substantially homogeneously dispersed and generally not crystalline. A key feature of the present materials is that the presence of the structurally dissimilar metal results in sufficient strain produced in the final multimetal oxy-hydroxide material to prevent crystallization from occurring. The resulting materials are specifically not annealed at temperatures that would induce crystallization in order to avoid the expected phase segregation that would occur during crystallization.
Type:
Grant
Filed:
January 30, 2017
Date of Patent:
January 25, 2022
Assignee:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Inventors:
Bo Zhang, Xueli Zheng, Oleksandr Voznyy, Sjoerd Hoogland, Jixian Xu, Min Liu, Cao-Thang Dinh, Edward Sargent
Abstract: This disclosure is directed to novel CD133-binding agents. The disclosure is also directed to uses of novel CD133-binding agents for detecting CD133-expressing cells and/or quantitating levels of cellular CD133 expression, for targeting CD133-expressing cells, for decreasing levels of CD133 in CD133-expressing cells and for treating or preventing cancer.
Type:
Grant
Filed:
October 19, 2017
Date of Patent:
January 11, 2022
Assignees:
The Governing Council of the University of Toronto, McMaster University
Inventors:
Jason Moffat, Jarrett Adams, Guohua Pan, Sachdev Sidhu, Rashida Williams, Xiaoyu Zhang, Sheila K. Singh, Parvez Vora, Chitra Venugopal
Abstract: An electric vehicle fast charger and methods thereof are described, adapted for re-use of magnetic components of an electric vehicle having traction converters when the electric vehicle is stationary and connected to a power grid. A switching stage provided by one or more sets of switches is controlled complementarily with the switches of the traction converters to (i) provide inversion of a grid voltage and (ii) shape current of the grid current between the electric vehicle and the power grid to track a waveshape of the grid voltage. A single switching stage and a dual switching stage circuit are contemplated, along with switch controller circuits, and instruction sets for switch control. Variants provide for energy transfer to accommodate for energy imbalances between storage devices.
Type:
Grant
Filed:
October 12, 2018
Date of Patent:
January 4, 2022
Assignees:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, ELEAPPOWER LTD.
Inventors:
Peter Lehn, Theodore Soong, Philippe Gray, Sepehr Semsar
Abstract: Some embodiments of the present disclosure provide a deep-learning-based framework for designing components of a downlink precoding system. The components of such a system include downlink training pilots and channel estimation based on receipt of the downlink training pilots. Another component involves channel measurement and feedback strategy at the user equipment. The components include a precoding scheme designed at the base station based on the feedback from the user equipment.
Type:
Application
Filed:
June 26, 2020
Publication date:
December 30, 2021
Applicants:
HUAWEI TECHNOLOGIES CANADA CO., LTD., THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO