Abstract: Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective nonself-propagating viral particles are disclosed. The viral vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and drugs.
Type:
Grant
Filed:
December 21, 1992
Date of Patent:
March 25, 1997
Assignee:
Theriod Biologics, Incorporated
Inventors:
Gail P. Mazzara, Bryan Roberts, Dennis L. Panicali, Virginia Stallard, Linda R. Gritz, Anna Mahe