Abstract: A surgical stapling device is provided for clamping and stapling tissue, and for dispensing a fluid such as an adhesive onto the tissue. The adhesive can be stored within one or more rigid chambers within removable cartridge and dispensed from a plurality of passageways within the cartridge. A plurality of staples and staple drivers are located in the cartridge and may be isolated from the fluid. Both linear and rotary members can be provided to dispense the fluid from the cartridge. Alternately, the fluid can be dispensed from the cartridge at any time with an operator actuatable control. A removable staple cartridge cover can be provided to seal the fluid in the cartridge and prevent fluid loss. Alternately, a fluid cartridge can be provided that can mount within a surgical stapling device and dispense one or more firings of a fluid therefrom.