Patents Assigned to Thione International, Inc.
  • Patent number: 6470894
    Abstract: A composition for inclusion within a cigarette, cigar, pipe or smokeless tobacco. The composition can be included within the tobacco itself, a filter for filtering tobacco smoke once burned or even within the paper or wrapper surrounding the tobacco product. In the cigarette filter, be it internal or external filters, the antioxidant complex is capable of scavenging and neutralizing the free radicals emanating from the burning or heated tobacco and passing through the filter as the smoker inhales. The composition is also capable of reducing free radical damage to the oro-pharyngeal cavity, respiratory tract and lungs resulting from tobacco smoke. The composition includes glutathione and preferably L-glutathione and green tea and/or grape seed extract.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: October 29, 2002
    Assignee: Thione International, Inc.
    Inventors: Theodore Hersh, Rebecca Hersh
  • Patent number: 6415798
    Abstract: A composition for inclusion within a cigarette, cigar, pipe or smokeless tobacco. The composition can be included within the tobacco itself, a filter for filtering tobacco smoke once burned within the paper or wrapper surrounding the tabacco product. In the cigarette filter, be it internal or external filters, the antioxidant complex is capable of scavenging and neutralizing the free radicals emanating from the burning or heated tobacco and passing through the filter as the smoker inhales. The composition is also capable of reducing free radical damage to the oro-pharyngeal cavity, respiratory tract and lungs resulting from tobacco smoke. The composition includes glutathione and preferaby L-glutathione and sources of the antioxidant enzymes catalase and superoxide dismutase.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: July 9, 2002
    Assignee: Thione International, Inc.
    Inventors: Theodore Hersh, Rebecca Hersh
  • Patent number: 6337320
    Abstract: A composition of L-glutathione (reduced) and selenium and an epidermal growth factor in a topical carrier and method of using the composition to reduce and repair ultraviolet radiation-induced skin damage, both acute injury (sunburn) and chronic damage (photoaging and cutaneous malignancies).
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: January 8, 2002
    Assignee: Thione International, Inc.
    Inventors: Theodore Hersh, Michael A. Warshaw
  • Patent number: 6303651
    Abstract: A composition and method of treating cutaneous infection and resulting inflammation in animals known as hot spots and mange, respectively, as well as related veterinarian dermatological conditions. The composition includes L-glutathione and a source of selenium which act synergistically and which are included in a suitable topical carrier for topical application.
    Type: Grant
    Filed: September 23, 1999
    Date of Patent: October 16, 2001
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 6242010
    Abstract: Compositions for remediating ano-rectal inflammatory processes, hemorrhoidal syndromes and ano-rectal wounds. The composition includes the synergistic combination of reduced glutathione and selenium as a selenoamino acid in a suitable carrier for topical applications.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: June 5, 2001
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 6228347
    Abstract: A gel, paste, gum or lozenge composition for oral application to human gums to prevent and reduce symptoms of gum disease. The composition includes reduced glutathione and a source of selenium.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: May 8, 2001
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 6138683
    Abstract: A composition for inclusion within a quantity of smokeless tobacco. The composition of antioxidants is capable of reducing free radical damage to the oro-pharyngeal cavity of a user resulting from consumption of smokeless tobacco. The composition includes L-glutathione and a source of selenium.
    Type: Grant
    Filed: November 3, 1998
    Date of Patent: October 31, 2000
    Assignee: Thione International, Inc.
    Inventors: Ted Hersh, Rebecca Hersh
  • Patent number: 6011067
    Abstract: The present invention deals with the combination of several synergistic antioxidants including enzymatic co-factors as adjuncts to therapy of desquamating inflammatory disorders, such as psoriasis. These topical compositions are aimed to neutralize free radical species generated by such inflammatory conditions which are responsible for certain clinical signs and symptoms. As such, damage to skin causing destruction of elastin and collagen tissues is reduced. The present synergistic antioxidants may be combined with anti-inflammatories, including corticosteroids, anti-microbials, including zinc pyrithione, and other preparations useful in the therapy of desquamating disorders as psoriasis, seborrhoeic dermatitis and related skin and scalp conditions.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: January 4, 2000
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 5922346
    Abstract: A composition for reducing free radical damage induced by tobacco products and environmental pollutants. The composition includes reduced glutathione and a source of selenium. The composition can be administered orally in the form of a gel, lozenge, tablet or gum.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: July 13, 1999
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 5906811
    Abstract: The combination of several synergistic antioxidants, enzymatic co-factors and amino acids in appropriate delivery vehicles employed in aerosol carriers, mist and pump oral sprays, solutions, such as oral irrigators, mouth rinses and mouthwashes, or gels and solid compositions as a means of preventing and ameliorating signs and symptoms and complications to the oro-pharyngeal cavity and mouth including buccal mucosa, gums and tongue and the upper respiratory tract from damage caused by free radical species induced by tobacco smoke, smokeless tobacco, ingested or chewed noxious, malodorous or harmful substances and other inhaled environmental pollutants and particulate matter, including tobacco to secondary smokers.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: May 25, 1999
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 5840681
    Abstract: A composition of glutathione and selenoamino acid in a topical carrier and method of using the composition to reduce and repair x-ray radiation-induced skin damage.
    Type: Grant
    Filed: September 15, 1997
    Date of Patent: November 24, 1998
    Assignee: Thione International, Inc.
    Inventors: Theodore Hersh, Michael A. Warshaw
  • Patent number: 5829449
    Abstract: A composition for inclusion within a cigarette, cigar or pipe. The composition can be included within the tobacco itself, a filter for filtering tobacco smoke once burned or even within the paper or wrapper surrounding the tobacco product. The composition is capable of reducing free radical damage to the oro-pharyngeal cavity, respiratory tract and lungs resulting from tobacco smoke. The composition includes L-glutathione and a source of selenium such as selenomethionine.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: November 3, 1998
    Assignee: Thione International, Inc.
    Inventors: Theodore Hersh, Rebecca Hersh
  • Patent number: 5827886
    Abstract: A composition and method of using it for ameliorating inflammatory reactions and painful and other symptoms of the diseases of arthritis, lumbago, low back pain, myalgias and neuralgias. The composition includes reduced glutathione, a selenoamino acid and an anesthetic, such as capsaicin, in a suitable carrier for topical application.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: October 27, 1998
    Assignee: Thione International, Inc.
    Inventor: Theodore Hersh
  • Patent number: 5667791
    Abstract: A composition of glutathione and selenoamino acid in a topical carrier and method of using the composition to reduce and repair x-ray radiation-induced skin damage.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: September 16, 1997
    Assignee: Thione INternational, Inc.
    Inventors: Theodore Hersh, Michael A. Warshaw