Abstract: An intravascular implant and methods of using the implant within the vasculature of the body, for example near a vascular aneurysm, are disclosed. A method of treating an aneurysm includes positioning a vascular graft comprising a tubular channel having a first end and a second end in a blood vessel, securing the vascular graft in place with an expandable anchoring member, and filling a seal cuff on the vascular graft, wherein the seal cuff extends radially outward beyond an exterior surface of the vascular graft, wherein the seal cuff comprises a first seal portion and a second seal portion and wherein the first seal portion is separated from the second seal portion by a first gap and a second gap along a circumference of the seal cuff.

Abstract: Non-expandable space-occupying devices for treating voids within the body are disclosed. The devices can have multiple non-expandable space-occupying elements connected to a flexible leader. Methods of making and using the devices are also disclosed.

Abstract: An intravascular implant and methods of using the implant within the vasculature of the body, for example near a vascular aneurysm, are disclosed. The method of attaching a second implant, such as a vascular graft, to the intravascular implant is also disclosed. The implant can be made from an anchor, a connector and a seal.

Abstract: The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Abstract: Tissue approximation devices for the minimally invasive approximation of muscle or fascia, such as approximation of the rectus muscles in the abdomen (abdominoplasty), or hernia repair and other such applications using minimally invasive methods to access and perform the procedures thereby reducing or eliminating visible scars.

Abstract: Veins are removed using a pull catheter introduced over a guidewire which extends between first and second percutaneous access points. Optionally, a side branch management tool including an excision device and/or a viewing scope can be advanced over the same guidewire in the direction opposite to that of the pull catheter. In that way, as the pull catheter inverts the vein being removed, side branches can be selectively viewed and/or severed using the side branch management tool. Arteriovenous fistulas are formed by inverting a length of a vein, mobilizing the inverted length relocating the mobilized end of the vein, and connecting the mobilized end to an artery.

Abstract: A catheter assembly for performing transmyocardial revascularization through the coronary arteries or veins, and a method of using this assembly for creating TMR channels through the myocardium coronary artery shunts through the myocardium and a device and method for injecting therapeutic agents into TMR channels interoperatively, together with a number of therapeutic agents.

Abstract: Opposable surgical clamp members having opposable resilient pads with wedge-shaped and cylindrical protrusions extending from the surfaces of the pads and the use of such members for occluding vessels and other tubular body structures are described. The protrusions are arranged such that when the members are moved toward one another, the protrusions of one pad interdigitate with the protrusions of the other pad. Upon engagement with a vessel, portions of the vessel are forced into the interdigital spaces providing for improved gripping of the vessel. The protrusions also resist lateral or transverse movement of a clamped vessel relative to the pads. The existence of through holes under the pad surface alters the relative resiliency of the pad, allowing for an overall pad resiliency that minimizes trauma to a clamped vessel while allowing the local resiliency of the protrusions themselves to be of a hardness to avoid excessive deflection and retain the desired shape and gripping ability.

Abstract: Opposable surgical clamp members having opposable resilient pads with wedge-shaped and cylindrical protrusions extending from the surfaces of the pads and the use of such members for occluding vessels and other tubular body structures are described. The protrusions are arranged such that when the members are moved toward one another, the protrusions of one pad interdigitate with the protrusions of the other pad. Upon engagement with a vessel, portions of the vessel are forced into the interdigital spaces providing for improved gripping of the vessel. The protrusions also resist lateral or transverse movement of a clamped vessel relative to the pads. The existence of through holes under the pad surface alters the relative resiliency of the pad, allowing for an overall pad resiliency that minimizes trauma to a clamped vessel while allowing the local resiliency of the protrusions themselves to be of a hardness to avoid excessive deflection and retain the desired shape and gripping ability.

Abstract: A minimally invasive device for performing direct cardiac massage including an inflatable bladder mounted on a rigid inflation tube. The rigid inflation tube is used to push the bladder into the sternocostal space through an incision in the upper abdomen just below the xiphoid process. After insertion into the sternocostal space, the bladder is repeatedly inflated and deflated to massage the heart and provide blood flow.

Abstract: A catheter assembly for performing transmyocardial revascularization through the coronary arteries or veins, and a method of using this assembly for creating TMR channels through the myocardium coronary artery shunts through the myocardium and a device and method for injecting therapeutic agents into TMR channels interoperatively, together with a number of therapeutic agents.

Abstract: A laparoscopic technique for harvesting the inferior epigastric artery and removing it from the body. The harvested inferior epigastric artery may be used as a bypass graft in a coronary or peripheral bypass operation.

Abstract: A catheter assembly for performing transmyocardial revascularization through the coronary arteries or veins, and a method of using this assembly for creating TMR channels through the myocardium coronary artery shunts through the myocardium.

Abstract: A soluble capsule, fairing or adherent material for a stent catheter or other device to inserted into the human body. The capsule, fairing or adherent material is made of a material which dissolves within the body in a convenient time, for example ten or fifteen minutes, allowing a convenient time for placement of the device and protecting the blood vessel from any sharp surfaces of the device.

Abstract: A pressure-based irrigation accumulator system utilizable in an angioscopy imaging system includes reservoir means for storing irrigation solution under pressure, pressure means for pressurizing the reservoir means to a preset pressure limit, and delivery means for delivering irrigation solution from the reservoir means to a destination.

Abstract: A method of rolling a defibrillator electrode inserts one side of a defibrillator electrode within a recess of a first handle, the recess located at one end of the first handle, inserts an opposite side of the defibrillator electrode within a recess of a second handle, the recess located at one end of the second handle, wherein the first and second handles are then rotated toward each other about their respective axes. An apparatus for rolling a defibrillator electrode includes a first handle having a recess at one of its ends operative to slidably grasp one side of a defibrillator electrode, and a second handle, the second handle having a recess at one of its ends operative to slidably grasp an opposite side of the defibrillator electrode.

Abstract: Improved implantable defibrillator electrodes and methods of implanting such electrodes are disclosed. One embodiment of the defibrillator electrodes includes a flexible conductive mesh and non-conductive mesh. Another embodiment of the defibrillator electrodes includes a flexible conductive mesh, a non-conductive mesh and an insulator therebetween. A third embodiment of the defibrillator electrode compensates for the shape of a human heart.Methods for implanting the defibrillator electrodes include rolling an electrode and inserting the rolled electrode into a subxiphoid opening while thorascopically observing the insertion and manipulation of the defibrillator electrode.

Abstract: In a method of making a surgical valve, a sealing body is attached inside one end of a braided sleeve, the other end of which is threaded through the bore of a toroidal body. The braided sleeve, toroidal body, and sealing body are inserted into the bore of a substantially cylindrical valve body. The sealing body generally has an axial passage extending through it which is axially aligned with the toroidal body. The braided sleeve is also typically coaxial with the axial passage and extends from the sealing body, and a device that selectively changes the relative axial positions of the sealing body and the extended part of the braided sleeve elongates the braided sleeve. This causes the braided sleeve to contract radially, which compresses the axial passage of the sealing body radially.

Abstract: An apparatus formed of a flexible coil concentrically disposed around a flexible wire includes one or more radially expansible, helically configured wire loops. The loops grip deposits within a vessel and allow the deposits to be sheared from the interior wall of the vessel when the apparatus is withdrawn from within the vessel.

Abstract: An adjustable surgical valve has a sealing body with an axial passage extending through it, a toroidal body axially aligned with the sealing body, and a device that selectively changes the relative axial positions of the sealing body and the toroidal body. The sealing body and the toroidal body have mating surfaces which radially compresses the axial passage of the sealing body when the relative axial positions of the sealing body and the toroidal body are changed. This causes the axial passage to seal with an instrument inserted into it, or the seal with itself if no instrument is inserted. Alternatively, or additionally, the sealing body may include a braided sleeve coaxial with the axial passage and extending from the sealing body, and a device that selectively changes the relative axial positions of the sealing body and the extended part of the braided sleeve to elongate the braided sleeve.