Patents Assigned to Tokyo University Agriculture and Technology TLO Co., Ltd.
  • Patent number: 8883462
    Abstract: A triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: November 11, 2014
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Keiji Hasumi, Yoshikazu Kitano, Hideo Ohishi, Haruki Koide, Keiko Hasegawa, Ritsuko Narasaki
  • Patent number: 8193173
    Abstract: The present invention relates to a liver function ameliorant containing orniplabin as an active ingredient thereof.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: June 5, 2012
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Keiji Hasumi, Fumihiko Maeda, Kunitoshi Mitsumori
  • Patent number: 8110596
    Abstract: The present invention provides a triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: February 7, 2012
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Keiji Hasumi, Yoshikazu Kitano, Hideo Ohishi, Haruki Koide, Keiko Hasegawa, Ritsuko Narasaki
  • Patent number: 7645340
    Abstract: A method for growing a crystal of an Al-containing III-V group compound semiconductor by the conventional HVPE method, characterized in that it comprises a step of reacting Al with hydrogen halide at a temperature of 700° C. or lower to form a halide of Al. The method has allowed the suppression of the formation of aluminum chloride (AlCl) or aluminum bromide (AlBr) reacting violently with quartz, which is the material of a reaction vessel for the growth, resulting in the achievement of the vapor phase growth of an Al-containing III-V group compound semiconductor at a rate of 100 microns/hr or more, which has lead to the mass-production of a substrate and a semiconductor element having satisfactory resistance to adverse environment.
    Type: Grant
    Filed: April 7, 2003
    Date of Patent: January 12, 2010
    Assignee: Tokyo University Agriculture and Technology TLO Co., Ltd.
    Inventors: Akinori Koukitu, Yoshinao Kumagai, Tomohiro Marui
  • Patent number: 7621999
    Abstract: An epitaxial growing method in which a crystal of AlxGa1-xN wherein x is a desirable constituent ratio can be grown on an Si substrate or sapphire substrate according to the HVPE process. Crystal of AlxGa1-xN is grown according to the HVPE process in which use is made of an aluminum material, a gallium material, an ammonia material and a carrier gas. The carrier gas consists of an inert gas and hydrogen, and the partial pressure of hydrogen is set so as to range from 0 to <0.1. As a result, the relationship between feeding ratio among materials and constituent ratio of grown crystal can be made linear, thereby enhancing the controllability of crystal composition.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: November 24, 2009
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd
    Inventors: Akinori Koukitu, Yoshinao Kumagai
  • Publication number: 20090216028
    Abstract: The present invention provides a triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Application
    Filed: March 20, 2007
    Publication date: August 27, 2009
    Applicant: Tokyo University of Agriculture and Technology TLO Co., LTD.
    Inventors: Keiji Hasumi, Yoshikazu Kitano, Hideo Ohishi, Haruki Koide, Keiko Hasegawa, Ritsuko Narasaki
  • Patent number: 7236444
    Abstract: An object of the present invention is to provide a wavefront aberration correcting device comprising a liquid crystal device that maximizes transmittance and minimizes light transmittance fluctuations even when the liquid crystal is driven by voltage.
    Type: Grant
    Filed: March 10, 2004
    Date of Patent: June 26, 2007
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Yasuhiro Takaki, Ei-ichiro Nishihara, Nobuyuki Hashimoto
  • Publication number: 20060104869
    Abstract: (Problems) A reaction container (apparatus) with a high efficiency, which can overcome problems of common chemically processing apparatuses using a solvent set where the compatible state and the separated state are reversibly changeable depending on a temperature, i.e. problems of the apparatus disclosed in Japanese Patent Application 2002-198242, namely the separation over time and spatial separation between compatible state and separated state. (Means for Solving the Problems) A temperature distribution is formed inside a reaction container, such that the temperature of one (optional) partial region inside the reaction container is the temperature for making first and second solvent solutions at a compatible state or a higher temperature, while the temperature of the other partial region is the temperature for making the solutions at a separated state or a lower temperature. Additionally, a reaction-promoting energy such as light and electricity is fed to the part at the compatible state.
    Type: Application
    Filed: August 29, 2003
    Publication date: May 18, 2006
    Applicant: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Kazuhiro Chiba, Tomohiro Marui
  • Publication number: 20050237897
    Abstract: An object of the present invention is to provide a wavefront aberration correcting device comprising a liquid crystal deivce that maximizes transmittance and minimizes light transmittance fluctuations even when the liquid crystal is driven by voltage.
    Type: Application
    Filed: March 10, 2004
    Publication date: October 27, 2005
    Applicant: TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD
    Inventors: Yasuhiro Takaki, Ei-ichiro Nishihara, Nobuyuki Hashimoto
  • Patent number: 6937939
    Abstract: A model for determining the type of soil, the water content of a soil, and the soil properties, and a soil measurement data storage portion (60) to store therein measurement data necessary to carry out the model and correlated with specific measurement conditions are provided. The water content is measured by a water content measuring portion (57) on the basis of the measurement data fed from a soil sensor (S). The type of soil is determined by a feature extracting portion (56) and a type-of-soil determining portion (58), and the determined type of soil is sent to a determining portion (59). The determining portion (59) determines corresponding conditions and a model according to the type of soil and water content of the measured place received and sets them in a predetermined processing portion.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: August 30, 2005
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Sakae Shibusawa, Shinichi Hirako, Atsushi Hisano, Kizo Yamazaki, Toru Takenobu
  • Patent number: 6853937
    Abstract: To provide a soil characteristics survey device capable of efficiently acquiring high precision data information about the distribution of soil characteristics in an agricultural field, and managing the data information collectively. The soil characteristics survey device is composed of a pedestal connected to the rear of the tractor, a control unit (a computer) mounted on the pedestal, and a soil excavating unit attached below the rear end of the pedestal. While being towed by a vehicle 2 such as a tractor, the device surveys in real time the distribution of soil characteristics in a given agricultural field. At the top of the control unit is attached a GPS antenna. The soil excavating unit 50 is composed of a shank 51 connected to the bottom of the pedestal and a sensing unit which is fixed so the bottom of the shank 51 and advance in the soil approximately parallel to the ground at a predetermined depth.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: February 8, 2005
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Sakae Shibusawa, Atsushi Ohtomo, Shinichi Hirako