Abstract: A viral vector comprising at least a portion of the genome of the HIV virus, a gene coding gp160 glycoprotein of the envelope of the HIV virus, as well as the elements providing for the expression of the glycoprotein in cells, wherein the gp160 is expressed as a non-cleavable protein.
Type:
Grant
Filed:
September 24, 1991
Date of Patent:
December 8, 1992
Assignee:
Transgene S.A., Institut Pasteur
Inventors:
Marie-Paule Kieny, Guy Rautmann, Jean-Pierre Lecocq, Simon W. Hobson, Marc Girard, Luc Montagnier