Patents Assigned to TransGenRx, Inc.
  • Gene Therapy Using Transposon-Based Vectors
    Publication number: 20120297493
    Abstract: Methods and compositions are presented for the administration of transposon-based vectors to an animal or human to provide gene therapy to the animal or human.
    Type: Application
    Filed: July 31, 2012
    Publication date: November 22, 2012
    Applicants: TransGenRx, Inc., The Board of Supervisors of Louisiana State Univ. and Agricultural and Mechanical College
    Inventors: Richard Cooper, Frederick M. Enright, William C. Fioretti
  • Administration of transposon-based vectors to reproductive organs
    Patent number: 8283518
    Abstract: Methods and compositions for the administration of transposon-based vectors to the reproductive organs of animals and the creation of transgenic animals. Preferred methods involve administration of the transposon-based vectors to the lumen of the oviduct of an avian, expression of a vector derived transgene in the avian, and deposition of the resultant polypeptide in an egg. This invention allows for large amounts of protein to be deposited in the egg.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 9, 2012
    Assignees: TransGenRx, Inc., The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard K. Cooper, William C. Fioretti, Gary G. Cadd
  • Gene therapy using transposon-based vectors
    Patent number: 8236294
    Abstract: Methods and compositions are presented for the administration of transposon-based vectors to an animal or human to provide gene therapy to the animal or human.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: August 7, 2012
    Assignees: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, TransGenRx, Inc.
    Inventors: Richard K. Cooper, Frederick M. Enright, William C. Fioretti
  • Gene therapy using transposon-based vectors
    Patent number: 8071364
    Abstract: Methods and compositions are presented for the administration of transposon based vectors to an animal or human to provide gene therapy to the animal or human.
    Type: Grant
    Filed: December 24, 2004
    Date of Patent: December 6, 2011
    Assignees: TransGenRx, Inc., The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard Cooper, Frederick M. Enright, William C. Fioretti
  • Gene Therapy Using Transposon-Based Vectors
    Publication number: 20110162096
    Abstract: Methods and compositions are presented for the administration of transposon-based vectors to an animal or human to provide gene therapy to the animal or human
    Type: Application
    Filed: November 8, 2010
    Publication date: June 30, 2011
    Applicants: College, TransGenRx, Inc.
    Inventors: Richard Cooper, Frederick M. Enright, William C. Fioretti
  • Production of Proteins Using Transposon-Based Vectors
    Publication number: 20100261227
    Abstract: Novel compositions for the in vitro or in vivo production of specific proteins are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes for the protein of interest, and the transposon-based vectors comprising these components. Also provided are methods of making these compositions and methods of using these compositions for the production of desired proteins in vivo or in transfected cells in vitro.
    Type: Application
    Filed: April 9, 2010
    Publication date: October 14, 2010
    Applicants: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, TransGenRx, Inc.
    Inventors: Richard K. Cooper, William C. Fioretti
  • Gene regulation in transgenic animals using a transposon-based vector
    Patent number: 7527966
    Abstract: Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further, these transgenic animals produce large quantities of desired molecules encoded by the transgene. Transgenic egg-laying animals produce large quantities of desired molecules encoded by the transgene and deposit these molecules in the egg.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: May 5, 2009
    Assignees: TransGenRx, Inc., The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard K. Cooper, Gary G. Cadd, William C. Fioretti, Kenneth F. De Boer