Patents Assigned to TRANSMURAL SYSTEMS LLC
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Patent number: 11980545Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. The disclosure also provides improved techniques for cardiac pacing.Type: GrantFiled: January 31, 2019Date of Patent: May 14, 2024Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee
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Patent number: 11950827Abstract: The disclosure provides various embodiments of catheters that can be used for various procedures. Embodiments of methods are also provided that can be performed with catheters in accordance with the present disclosure.Type: GrantFiled: November 1, 2020Date of Patent: April 9, 2024Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart Macdonald, Rany Busold, Alexis Balcom, Morgan House
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Patent number: 11871928Abstract: In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other.Type: GrantFiled: August 31, 2021Date of Patent: January 16, 2024Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Biwei MacDonald, Alana Rafiee
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Patent number: 11839543Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. Various embodiments of useful valve prostheses are also disclosed.Type: GrantFiled: April 30, 2019Date of Patent: December 12, 2023Assignee: Transmural Systems LLCInventor: Nasser Rafiee
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Patent number: 11567150Abstract: The present disclosure provides medical devices having MRI-compatible circuitry. Preferably, the devices do not project an enlarged profile, yet their position can be determined during an iMRI procedure. Illustrative embodiments of such a device can include a base surface, a first conducting layer disposed on the base surface, a first insulating layer disposed over at least a portion of the first conducting layer, and a second conducting layer disposed over at least a portion of the first insulating layer.Type: GrantFiled: April 23, 2021Date of Patent: January 31, 2023Assignee: Transmural Systems LLCInventors: Ozgur Kocaturk, Nasser Rafiee
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Patent number: 11357627Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.Type: GrantFiled: August 30, 2019Date of Patent: June 14, 2022Assignee: Transmural Systems LLCInventor: Nasser Rafiee
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Patent number: 11259926Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. The disclosure also provides improved techniques for cardiac pacing.Type: GrantFiled: January 31, 2019Date of Patent: March 1, 2022Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee
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Patent number: 11179156Abstract: In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other.Type: GrantFiled: April 30, 2019Date of Patent: November 23, 2021Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Robert J. Lederman, Kanishka Ratnayaka, Biwei MacDonald, Alana Rafiee
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Patent number: 11134934Abstract: In accordance with the disclosure, devices are provided for closing an opening in tissue. The devices include a proximal portion configured and arranged to occlude the tissue opening, and a distal anchor portion configured and arranged to anchor the device in the tissue opening. If desired, the distal anchor portion can be moved proximally or distally with respect to the proximal portion during implantation. The proximal portion can be configured and arranged to fit into a left atrial appendage of a patient, and further wherein the distal anchor portion is configured and arranged to extend into the left atrial appendage.Type: GrantFiled: August 17, 2020Date of Patent: October 5, 2021Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Ozgur Kocaturk
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Patent number: 11135061Abstract: Exemplary embodiments provide methods and systems for delivering a prosthesis to a target location in a lumenal system of a patient. At least one tether is secured proximate the target location to serve as a rail, and a prosthesis is advanced along the rail to the target location and secured in place. Exemplary methods and systems provide for repair of the mitral and tricuspid valves, as well as abdominal aortic aneurysms, stomach valves, fallopian tubes and the pulmonary system, among others. Also disclosed are various prostheses suitable for use with the disclosed methods and systems.Type: GrantFiled: April 30, 2019Date of Patent: October 5, 2021Assignee: Transmural Systems LLCInventor: Nasser Rafiee
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Patent number: 11039923Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. The disclosure also provides improved techniques for cardiac pacing.Type: GrantFiled: January 31, 2019Date of Patent: June 22, 2021Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee
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Patent number: 11007059Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. The disclosure also provides improved techniques for cardiac pacing.Type: GrantFiled: January 31, 2019Date of Patent: May 18, 2021Assignee: Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee
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Patent number: 10449046Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. Various embodiments of useful valve prostheses are also disclosed.Type: GrantFiled: August 6, 2014Date of Patent: October 22, 2019Assignee: Transmural Systems LLCInventor: Nasser Rafiee
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Patent number: 10433962Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. An improved protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve.Type: GrantFiled: October 27, 2017Date of Patent: October 8, 2019Assignees: Transmural Systems LLC, The United States of America, as Represented by the Secretary, Department of Health and Human ServicesInventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee, Rany Busold, Robert J. Lederman, Toby Rogers
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Patent number: 10426482Abstract: In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other.Type: GrantFiled: September 15, 2016Date of Patent: October 1, 2019Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Transmural Systems LLCInventors: Nasser Rafiee, Stuart MacDonald, Robert J. Lederman, Kanishka Ratnayaka, Biwei MacDonald, Alana Rafiee
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Patent number: 10398551Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.Type: GrantFiled: January 23, 2017Date of Patent: September 3, 2019Assignee: Transmural Systems LLCInventor: Nasser Rafiee
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Patent number: 10321998Abstract: Exemplary embodiments provide methods and systems for delivering a prosthesis to a target location in a lumenal system of a patient. At least one tether is secured proximate the target location to serve as a rail, and a prosthesis is advanced along the rail to the target location and secured in place. Exemplary methods and systems provide for repair of the mitral and tricuspid valves, as well as abdominal aortic aneurysms, stomach valves, fallopian tubes and the pulmonary system, among others. Also disclosed are various prostheses suitable for use with the disclosed methods and systems.Type: GrantFiled: May 3, 2013Date of Patent: June 18, 2019Assignee: Transmural Systems LLCInventor: Nasser Rafiee
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Patent number: 10058315Abstract: The present disclosure provides a variety of prostheses, delivery systems and techniques to facilitate closure of transvascular or transcameral access ports. Various embodiments of prostheses are provided including a plurality of radially expandable mesh discs filled with material to facilitate coagulation and to reduce or stop leakage from punctures in vessel walls.Type: GrantFiled: September 27, 2016Date of Patent: August 28, 2018Assignees: Transmural Systems LLC, The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Nasser Rafiee, Stuart MacDonald, Robert J. Lederman, Toby Rogers, Rany Busold, Koosha Rafiee
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Patent number: 10045765Abstract: The present disclosure provides a variety of prostheses, delivery systems and techniques to facilitate closure of transvascular or transcameral access ports. Various embodiments of prostheses are provided including a plurality of radially expandable discs that can be filled with material to facilitate coagulation and to reduce or stop leakage from punctures in vessel walls.Type: GrantFiled: July 31, 2017Date of Patent: August 14, 2018Assignees: Transmural Systems LLC, The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Nasser Rafiee, Stuart MacDonald, Robert J. Lederman, Toby Rogers, Rany Busold, Koosha Rafiee
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Patent number: 9579193Abstract: Exemplary embodiments provide methods and systems for delivering a prosthesis to a target location in a lumenal system of a patient. At least one tether is secured proximate the target location to serve as a rail, and a prosthesis is advanced along the rail to the target location and secured in place. Exemplary methods and systems provide for repair of the mitral and tricuspid valves, as well as abdominal aortic aneurysms, stomach valves, fallopian tubes and the pulmonary system, among others. Also disclosed are various prostheses suitable for use with the disclosed methods and systems.Type: GrantFiled: May 3, 2013Date of Patent: February 28, 2017Assignee: Transmural Systems LLCInventor: Nasser Rafiee