Abstract: A device for delivering beneficial agents such as drugs orally for sustained time periods comprising a support member that is formfit or clasped over or around the teeth and one or more reservoir members that is/are carried on an exterior surface of the support along the labial, buccal or lingual surfaces of the teeth and is adapted to hold the agent and release it to the oral cavity for achieving a local effect within the mouth, an effect elsewhere in the gastrointestinal tract or systemically.
Type:
Grant
Filed:
January 3, 1992
Date of Patent:
March 16, 1993
Assignee:
Transpharm Group, Inc.
Inventors:
Gabriel L. Garay, Robert Tacy, Anne-Ly Garay
Abstract: A removable inflatable beneficial agent delivery device that is adapted to reside in the stomach for a prolonged time period. The device comprises (1) an inflatable member which in its deflated state can be inserted into the stomach via a naso-gastric tube and which in its inflated state resides comfortably in the stomach but cannot pass through the pyloric sphincter, (2) an inflation tube connected to the inflatable member by which the inflatable member can be inflated from outside the body and which is dropped into the stomach after inflation, and (3) one or more agent-containing cartridges that are carried exteriorly on the inflatable member or the inflation tube and are capable of delivering agent to the gastrointestinal tract over a prolonged time period.
Abstract: A tooth-anchored beneficial agent delivery device comprising an anchor-member that is semipermanently attached to a tooth, such as by an adhesive, bonding or a tooth-encircling band, and one or more agent-carrying cartridges that are removably connected to the anchor member such as by a ball-and-socket mechanism.
Type:
Grant
Filed:
June 13, 1988
Date of Patent:
August 29, 1989
Assignee:
Transpharm Group
Inventors:
Gabriel L. Garay, Anne-Ly Garay, Robert Tacy