Abstract: The use of an agent in the manufacture of a medicament to affect an allergic condition and/or a hypersensitivity condition is described. The agent is capable of modulating a ganglioside associated activity. The agent is not coupled to an antigen. The modulation of the ganglioside associated activity affects an allergic condition and/or a hypersensitivity condition.
Type:
Grant
Filed:
January 18, 2013
Date of Patent:
March 31, 2015
Assignee:
Trident Pharmaceuticals, Inc.
Inventors:
Neil Andrew Williams, Timothy Raymond Hirst, John Bienenstock
Abstract: The use of an agent in the manufacture of a medicament to affect an allergic condition and/or a hypersensitivity condition is described. The agent is capable of modulating a ganglioside associated activity. The agent is not coupled to an antigen. The modulation of the ganglioside associated activity affects an allergic condition and/or a hypersensitivity condition.
Abstract: The use of an agent in the manufacture of a medicament to affect an allergic condition and/or a hypersensitivity condition is described. The agent is capable of modulating a ganglioside associated activity. The agent is not coupled to an antigen. The modulation of the ganglioside activity affects an allergic condition and/or a hypersensitivity condition.
Type:
Grant
Filed:
March 27, 2007
Date of Patent:
January 22, 2013
Assignee:
Trident Pharmaceuticals, Inc.
Inventors:
Neil Andrew Williams, Timothy Raymond Hirst, John Bienenstock
Abstract: A method for treating an rheumatoid arthritis in a mammalian subject in need of same wherein the method comprises: administering to the mammalian subject an agent capable of modulating a ganglioside GM-1 associated activity in an amount effective to treat the disease.
Type:
Application
Filed:
June 27, 2011
Publication date:
January 5, 2012
Applicant:
Trident Pharmaceuticals, Inc.
Inventors:
Neil A. Williams, Timothy R. Hirst, Toufic O. Nashar
Abstract: A method for stimulating the immune response to a vaccine applied to a mammalian subject includes the step of administering to the subject an effective amount of EtxB or a molecule having substantially equivalent activity, free from whole toxin and not linked to an antigen.
Type:
Grant
Filed:
May 10, 1999
Date of Patent:
March 29, 2011
Assignee:
Trident Pharmaceuticals, Inc.
Inventors:
Timothy Raymond Hirst, Neil Andrew Williams, Andrew Morgan, Andrew Douglas Wilson, Lucy Amber Bird
Abstract: A method for treating an rheumatoid arthritis in a mammalian subject in need of same wherein the method comprises: administering to the mammalian subject an agent capable of modulating a ganglioside GM-1 associated activity in an amount effective to treat the disease.
Type:
Application
Filed:
September 14, 2009
Publication date:
June 3, 2010
Applicant:
TRIDENT PHARMACEUTICALS, INC.
Inventors:
NEIL ANDREW WILLIAMS, TIMOTHY RAYMOND HIRST, TOUFIC OSMAN NASHAR
Abstract: This application relates to methods for modulating an immune response in a mammalian subject in need of prevention against or treatment of diabetes comprising the administration of EtxB and/or insulin.
Type:
Grant
Filed:
September 30, 2005
Date of Patent:
September 15, 2009
Assignee:
Trident Pharmaceuticals, Inc.
Inventors:
Neil Andrew Williams, Timothy Raymond Hirst, Toufic Osman Nashar
Abstract: The use of an agent in the manufacture of a medicament to affect an allergic condition and/or a hypersensitivity condition is described. The agent is capable of modulating a ganglioside associated activity. The agent is not coupled to an antigen. The modulation of the ganglioside associated activity affects an allergic condition and/or a hypersensitivity condition.
Type:
Grant
Filed:
January 8, 1999
Date of Patent:
April 24, 2007
Assignee:
Trident Pharmaceuticals, Inc.
Inventors:
Neil Andrew Williams, Timothy Raymond Hirst, John Bienenstock