Patents Assigned to Trigemina, Inc.
  • Publication number: 20190175686
    Abstract: Disclosed are methods and compositions for the treatment of autism spectrum disorder, related disorders and symptoms of such disorders, comprising co-administration of an oxytocin peptide and magnesium ions. Co-administration of an oxytocin peptide and magnesium ions results in a synergistic or enhanced effect on reducing social and communication deficits in a patient suffering from an autism spectrum disorder.
    Type: Application
    Filed: April 12, 2017
    Publication date: June 13, 2019
    Applicant: Trigemina, Inc.
    Inventors: Dean CARSON, David C. YEOMANS
  • Publication number: 20170368095
    Abstract: Disclosed are magnesium-containing oxytocin peptide formulations or compositions comprising an oxytocin peptide and a magnesium salt that produces synergistic analgesia when used in treating pain. Also disclosed are methods for the treatment of pain (such as migraine headache) comprising co-administration of an oxytocin peptide and a magnesium salt.
    Type: Application
    Filed: January 7, 2016
    Publication date: December 28, 2017
    Applicant: Trigemina, Inc.
    Inventors: David C. YEOMANS, Dean CARSON, Ramachandran THIRUCOTE
  • Patent number: 9629894
    Abstract: Disclosed are magnesium-containing oxytocin peptide formulations or compositions comprising an oxytocin peptide and a magnesium salt that produces synergistic analgesia when used in treating pain. Also disclosed are methods for the treatment of pain (such as migraine headache) comprising co-administration of an oxytocin peptide and a magnesium salt.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: April 25, 2017
    Assignee: TRIGEMINA, INC.
    Inventors: David C. Yeomans, Dean Carson, Ramachandran Thirucote
  • Patent number: 8501691
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: August 6, 2013
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research & Education
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Publication number: 20130196908
    Abstract: The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
    Type: Application
    Filed: March 13, 2013
    Publication date: August 1, 2013
    Applicant: TRIGEMINA, INC.
    Inventor: TRIGEMINA, INC.
  • Patent number: 8258096
    Abstract: The present invention relates to methods for the treatment or prevention of trigeminal nerve-associated pain, in particular chronic, acute and procedural-related pain. The methods comprise administration of analgesic agents to the trigeminal nerve system which results in analgesia to the facial or head region.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: September 4, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, William H. Frey, II, Daniel I. Jacobs, Martin S. Angst
  • Patent number: 8252745
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: August 28, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Patent number: 8202838
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: June 19, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Patent number: 8198240
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: June 12, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs