Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin isocitric acid.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin malic acid.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin tropic acid.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle 3-phenyllactic acid or a topically effective salt thereof.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle 2-phenyllactic acid or a topically effective salt thereof.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle quinic acid or a topically effective salt thereof, or quinolactone.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle ribonic acid or a topically effective salt thereof, or ribonolactone.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle ethyl pyruvate.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle isocitric acid or a topically effective salt thereof.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle gluconic acid or a topically effective salt thereof or gluconolactone.

Abstract: Composition and method for enhancing therapeutic effects of topically applied agents are disclosed. The cosmetic or therapeutic composition may include one or more of cosmetic or pharmaceutical agents present in a total amount of from 0.01 to 40 percent and one or more of hydroxycarboxylic acids or related compounds present in a total amount of from 0.01 to 99 percent by weight of the total composition. The cosmetic and pharmaceutical agents may include but not limited to age spots, wrinkles and keratoses removing agents; vitamins; aloes; sun screens; tanning, depigmenting and shampooing agents; antiyeasts; antifungal, antibacterial and antiviral agents; topical bronchial dilators and topical cardiovascular agents; hormonal agents; vasodilators; retinoids and other dermatological agents. The hydroxycarboxylic acids and related compounds include organic alpha and beta hydroxycarboxylic acids, alpha and beta ketocarboxylic acids and salts thereof.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle saccharic acid or a topically effective salt thereof, or saccharolactone.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle mucic acid or a topically effective salt thereof, or mucolactone.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle tropic acid or a topically effective salt thereof.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle galacturonic acid or a topically effective salt thereof, or galacturonolactone.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle methyllactic acid or a topically effective salt thereof.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle benzilic acid or a topically effective salt thereof.

Abstract: Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, 2-hydroxypropanoic acid 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioicacid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone.