Patents Assigned to Trustess of Dartmouth College
  • Pulsed lasers in frequency domain diffuse optical tomography and spectroscopy
    Patent number: 8634082
    Abstract: A diffuse optical tomography system incorporating a mode-locked, tunable laser produces pulsed light that may be used to interrogate tissue with high spatial and spectral resolution. The detection signal may be heterodyne shifted to lower frequencies to allow easy and accurate measurement of phase and amplitude. Embodiments incorporating wavelength-swept, tunable, lasers and embodiments using broadband photonic fiber lasers with spectrally-sensitive detectors are described.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: January 21, 2014
    Assignee: The Trustess of Dartmouth College
    Inventors: Shudong Jiang, Brian William Pogue, Jia Wang, Keith D. Paulsen
  • Monocyclic cyanoenones and methods of use thereof
    Patent number: 8314137
    Abstract: The present invention features monocyclic cyanoenone compositions and methods for using the same in the treatment of diseases such as cancer, inflammatory diseases and neurodegenerative diseases.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: November 20, 2012
    Assignee: Trustess of Dartmouth College
    Inventors: Tadashi Honda, Emilie David, Dale Mierke