Abstract: Provided is an organic-inorganic hybrid composite of a polymerized cyclic nitroxide radical compound and inorganic nanoparticles. Such a composite is capable, for example, of maintaining a stable nanoparticle shape in gastric fluid, and can be used by itself or as a carrier for delivery of another drug to the intestines.
Type:
Grant
Filed:
February 6, 2013
Date of Patent:
May 10, 2016
Assignees:
UNIVERSITY OF TSUKUBA, TSUKUBA UNIVERSITY OF TECHNOLOGY
Inventors:
Yukio Nagasaki, Yutaka Ikeda, Toru Yoshitomi, Tatsuya Yaguchi, Mayo Yamashita, Md. Amran Hossain, Tomoki Yoshinari, Atsushi Ueda, Aki Hirayama
Abstract: A microshaft forming method and apparatus for forming a microshaft without requiring high level of stillness required by conventional methods. The microshaft forming apparatus comprises an elongated electrode (1) to be formed into a microshaft, a forming plate (3) for forming the electrode (1), electrode rotating means for rotating the electrode (1) around the length direction (1a) of the electrode (1), a discharge machining power supply (5) for applying a voltage between the electrode (1) and the forming plate (3) to cause discharge between the electrode (1) and the forming plate (3), and electrode moving means for traversing the electrode (1) rotated by the electrode rotating means across the forming plate (3) from the side edge surface (3a) of the forming plate (3).
Type:
Application
Filed:
November 9, 2006
Publication date:
July 2, 2009
Applicants:
The University of Tokyo, National University Corporation Tsukuba University of Technology