Patents Assigned to Tunghai University
  • Patent number: 11937932
    Abstract: An acute kidney injury predicting system and a method thereof are proposed. A processor reads the data to be tested, the detection data, the machine learning algorithm and the risk probability comparison table from a main memory. The processor trains the detection data according to the machine learning algorithm to generate an acute kidney injury prediction model, and inputs the data to be tested into the acute kidney injury prediction model to generate an acute kidney injury characteristic risk probability and a data sequence table. The data sequence table lists the data to be tested in sequence according to a proportion of each of the data to be tested in the acute kidney injury characteristics. The processor selects one of the medical treatment data from the risk probability comparison table according to the acute kidney injury characteristic risk probability.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: March 26, 2024
    Assignees: TAICHUNG VETERANS GENERAL HOSPITAL, TUNGHAI UNIVERSITY
    Inventors: Chieh-Liang Wu, Chun-Te Huang, Cheng-Hsu Chen, Tsai-Jung Wang, Kai-Chih Pai, Chun-Ming Lai, Min-Shian Wang, Ruey-Kai Sheu, Lun-Chi Chen, Yan-Nan Lin, Chien-Lun Liao, Ta-Chun Hung, Chien-Chung Huang, Chia-Tien Hsu, Shang-Feng Tsai
  • Patent number: 11908136
    Abstract: A respiratory status classifying method is for classifying as one of at least two respiratory statuses and includes an original physiological parameter inputting step, an original chest image inputting step, a characteristic physiological parameter generating step, a characteristic chest image generating step, a training step and a classifier generating step. The characteristic chest image generating step includes processing at least a part of the original chest images, segmenting images of a left lung, a right lung and a heart from each of the original chest images that are processed, and enhancing image data of the images being segmented, so as to generate a plurality of characteristic chest images. The training step includes training two respiratory status classifiers using a plurality of characteristic physiological parameters and the characteristic chest images by at least one machine learning algorithm.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: February 20, 2024
    Assignees: TAICHUNG VETERANS GENERAL HOSPITAL, TUNGHAI UNIVERSITY
    Inventors: Ming-Cheng Chan, Kai-Chih Pai, Wen-Cheng Chao, Yu-Jen Huang, Chieh-Liang Wu, Min-Shian Wang, Chien-Lun Liao, Ta-Chun Hung, Yan-Nan Lin, Hui-Chiao Yang, Ruey-Kai Sheu, Lun-Chi Chen
  • Patent number: 11866899
    Abstract: A triadic recurve implosion flood navigation for in-situ tailoring yearn system—[TRINITY-D20] has a tailoring mechanism comprising a first unit having an arc-shaped first arcuate portion, and a second unit having an arc-shaped second arcuate portion, the first and second units stagger each other with concave arcuate surfaces facing opposite directions by center axes of curvature of the first and second arcuate portions parallelling each other to cause an arcuate end of the first arcuate portion locate between two arcuate ends of the second arcuate portion and separated from the concave arcuate surface of the second arcuate portion by a first distance, and to cause an arcuate end of the second arcuate portion locate between two arcuate ends of the first arcuate portion and separated from the first arcuate portion by a second distance, thereby the first and second arcuate portions jointly define a curved channel.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: January 9, 2024
    Assignee: TUNGHAI UNIVERSITY
    Inventors: Kuo-wei Chiu, Davina Doras Cranstoun
  • Publication number: 20230420818
    Abstract: A multi-layered resonator circuit structure and a multi-layered filter circuit structure. The multi-layered resonator circuit structure includes a multi-layered substrate, a plurality of resonators and a plurality of conductive components. The multi-layered substrate has a top surface, a bottom surface, and a ground layer. The top surface and the bottom surface face away from each other. The ground layer is located between the top surface and the bottom surface. A part of the plurality of resonators is/are disposed on the top surface. Another part of the plurality of resonators is/are disposed on the bottom surface. The plurality of conductive components is located in the multi-layered substrate. The plurality of resonators is electrically connected to the ground layer, respectively, via the plurality of conductive components.
    Type: Application
    Filed: March 14, 2023
    Publication date: December 28, 2023
    Applicants: UNIMICRON TECHNOLOGY CORP., TUNGHAI UNIVERSITY
    Inventors: Chi-Feng CHEN, Po-Sheng YEN, Ruey-Beei WU, Ra-Min TAIN, Chin-Sheng WANG, Jun-Ho CHEN
  • Patent number: 11591368
    Abstract: The invention pertains to cancer treatment or prevention field. Particularly, the invention provides peptide fragments from SLIT2 protein and their applications in inhibition of cancer growth, invasion and metastasis.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: February 28, 2023
    Assignees: CHUNG SHAN MEDICAL UNIVERSITY, TUNGHAI UNIVERSITY
    Inventors: Jinghua Tsai Chang, Feng-Di Lung
  • Patent number: 11406926
    Abstract: An air filtration system includes a main body having a flow path; a first filter portion provided on the flow path and having a first body portion; a plurality of protrusions distributed and disposed on the first body portion; and a plurality of first through holes passing through the first body portion and interposed between the adjacent protrusions; wherein when an external fluid flows in the flow path, the external fluid passes through the protrusions first and then passes through each of the first through holes, so that the flowing external fluid is hindered by the protrusions, and thus a flow velocity at a position adjacent to the protrusions is lower than a flow velocity flowing through the first through holes, thereby vortices are respectively generated between orifices of the first through holes and the adjacent protrusions.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: August 9, 2022
    Assignees: TUNGHAI UNIVERSITY
    Inventors: Kuo-Wei Chiu, Chien-Hung Lin, Angela Wang
  • Patent number: 11384150
    Abstract: An immunoconjugate, comprising an anti-EGFR antibody or a binding fragment thereof, and a kinase inhibitor.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: July 12, 2022
    Assignees: Development Center for Biotechnology, Tunghai University
    Inventors: Shih-Hsien Chuang, Wei-Ting Chao, Wei-Ting Sun, Hui-Jan Hsu, Wun-Huei Lin
  • Patent number: 10356988
    Abstract: This present invention disclosed a method for culturing Ophiocordyceps sinensis by inoculating a fungus inoculum onto a medium, culturing with a culturing condition in the dark room, and then culturing under the light for at least four weeks. According to the method for culturing O. sinensis disclosed in this present invention, the cultured O. sinensis has better growth rate and its composition and content of active ingredients are similar with wild O. sinensis.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: July 23, 2019
    Assignees: Tunghai University, Greenyn Biotechnology Co., Ltd
    Inventors: Fan-Chiang Yang, Yi-Chuan Shih
  • Patent number: 10100086
    Abstract: This present invention provides a novel peptide for inhibiting growth of microorganisms, a pharmaceutical composition, an antimicrobial composition comprising such novel peptide, and a method for inhibiting growth of microorganisms. The novel peptide for inhibiting growth of microorganisms has amino acid sequence: KX1LRX2X3X4RRWX5, wherein X1, X2, and X5 are selected from the group of W and R, respectively; X3 is selected from the group of V and P; and X4 is selected from the group of R and methylated W. The method for inhibiting growth of microorganisms disclosed in this present invention comprises administering the novel peptide, the pharmaceutical composition, or the antimicrobial composition.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: October 16, 2018
    Assignee: TUNGHAI UNIVERSITY
    Inventor: Feng-Di Lung
  • Patent number: 10002425
    Abstract: The method of segmenting single neuron images with high-dynamic-range thresholds of the present invention includes (a) preparing a biological tissue sample containing neurons and performing imaging to this sample to obtain a three-dimensional raw neuroimage; (b) deleting voxels in the three-dimensional raw neuroimage with signal intensities below a first signal intensity threshold to obtain a first thresholded image; (c) tracing the first thresholded image to obtain a first traced image; (d) calculating a structural importance score of every voxel in the first traced image to obtain a first structural importance score of every voxel; (e) gradually increasing the signal intensity threshold and repeating (b), (c) and (d) n?1 times; (f) summing up all the n structural importance scores of every voxel; (g) deleting voxels with summed structural importance score smaller than a pre-determined value from the raw image to obtain the segmented single neuron.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: June 19, 2018
    Assignees: National Tsing Hua University, Tunghai University, National Applied Research Laboratories
    Inventors: Chi-Tin Shih, Nan-Yow Chen, Ann-Shyn Chiang
  • Patent number: 9802982
    Abstract: This present invention provides a novel peptide for inhibiting growth of microorganisms, a pharmaceutical composition, an antimicrobial composition comprising such novel peptide, and a method for inhibiting growth of microorganisms. The novel peptide for inhibiting growth of microorganisms has amino acid sequence: KX1LRX2X3X4RRWX5, wherein X1, X2, and X5 are selected from the group of W and R, respectively; X3 is selected from the group of V and P; and X4 is selected from the group of R and methylated W. The method for inhibiting growth of microorganisms disclosed in this present invention comprises administering the novel peptide, the pharmaceutical composition, or the antimicrobial composition.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: October 31, 2017
    Assignee: TUNGHAI UNIVERSITY
    Inventor: Feng-Di Lung
  • Patent number: 9797838
    Abstract: This present invention relates to a screening method for rapidly identifying the hybridomas upon cell size and the expression of an exogenous label such as fluorescence labeling. This method of this present invention can largely shortens the time cost for antibody development by saving the time period with comparison of traditional methods using cell culture with media such as HAT medium.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: October 24, 2017
    Assignee: TUNGHAI UNIVERSITY
    Inventors: Chang-Chi Hsieh, Ming-Shiou Jan, Ai Shih, Chuan-Kai Chou, Yen-Wan Hsiao, Ying-Chun Lai
  • Patent number: 9458421
    Abstract: The invention discloses a culture method for Antrodia cinnamomea to elevate the amounts and types of the bioactive components in Antrodia cinnamomea through controlling the wavelength and intensity of the light. Furthermore, the modification of the environmental factors such as water content, composition and relative amount of the culture medium, and the culture temperature are capable of increasing the amounts and types of the bioactive components in Antrodia cinnamomea.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: October 4, 2016
    Assignees: TUNGHAI UNIVERSITY, GREENYN BIOTECHNOLOGY CO., LTD.
    Inventors: Fan-Chiang Yang, Chia-Li Wu, Ya-Chen Chi
  • Patent number: 9142410
    Abstract: A method for manufacturing a semiconductor nano layer structure includes: two substrates are provided; a plurality of semiconductor nanowires are formed on one of the substrates; an absorption surface is formed on the other substrate; one of the substrates is fixed on a cylindrical roller, the cylindrical roller is brought into contact with a surface of the substrate which is stationary and is not fixed on the cylindrical roller, and rolled with a constant velocity and pressure so that the semiconductor nanowires are break, detached, transferred and absorbed, and a semiconductor nano layer structure is formed on the stationary substrate; a de-laminating process is performed to separate the semiconductor nano layer structure from the second substrate; an electric Joule heat welding process is locally performed to bond each of the semiconductor nanowires of the semiconductor nano layer structure or each semiconductor nano layer structure.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: September 22, 2015
    Assignee: TUNGHAI UNIVERSITY
    Inventor: Hsi-Lien Hsiao
  • Patent number: 9034397
    Abstract: The present invention provides methods of administering a Dendrobium polyphenol in an amount effective to lower blood sugar, treat hepatic disease, obesity or diabetes. Exemplary hepatic disease includes fibrosis, fatty liver and hepatitis. Moreover, the Dendrobium polyphenol is extracted from the plants of the genus Dendrobium.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: May 19, 2015
    Assignee: Tunghai University
    Inventors: Chang-Chi Hsieh, Chin-Tung Wu, Jie-Yu Chen, Yi-Chieh Li, Hsin-Sheng Tsay
  • Patent number: 8990805
    Abstract: A method of dynamic resource allocation for a virtual machine cluster is to calculate the resource usage weight of the respective virtual machine, the resource usage weight of the respective physical machine, and the average resource usage weight of the physical machines, to pick the physical machine with the greatest resource usage weight as the migration source machine, to pick the physical machine with the least resource usage weight as the migration object machine, and to move the virtual machine in the migration source machine with the resource usage weight thereof being closest to the migration difference value to the migration object machine to achieve the effect of load balancing.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: March 24, 2015
    Assignee: Tunghai University
    Inventors: Chao-Tung Yang, Hsiang-Yao Cheng, Kuan-Chieh Wang
  • Publication number: 20150052639
    Abstract: The invention discloses a culture method for Antrodia cinnamomea to elevate the amounts and types of the bioactive components in Antrodia cinnamomea through controlling the wavelength and intensity of the light. Furthermore, the modification of the environmental factors such as water content, composition and relative amount of the culture medium, and the culture temperature are capable of increasing the amounts and types of the bioactive components in Antrodia cinnamomea.
    Type: Application
    Filed: January 6, 2014
    Publication date: February 19, 2015
    Applicants: Greenyn Biotechnology Co., Ltd., Tunghai University
    Inventors: Fan-Chiang YANG, Chia-Li WU, Ya-Chen CHI
  • Publication number: 20140288186
    Abstract: The present invention provides methods of administering a Dendrobium polyphenol in an amount effective to lower blood sugar, treat hepatic disease, obesity or diabetes. Exemplary hepatic disease includes fibrosis, fatty liver and hepatitis. Moreover, the Dendrobium polyphenol is extracted from the plants of the genus Dendrobium.
    Type: Application
    Filed: October 30, 2013
    Publication date: September 25, 2014
    Applicant: Tunghai University
    Inventors: Chang-Chi Hsieh, Chin-Tung Wu, Jie-Yu Chen, Yi-Chieh Li, Hsin-Sheng Tsay
  • Patent number: 8745621
    Abstract: A method for managing green power determines if how many physical machines should run or be shut off with the gross occupied resource weight ratio of the virtual machine cluster. The standby physical machine in the non-running physical machines is elected and woke up to join as one of the running physical machines; one of the running physical machines is elected as a migration physical machine with the virtual machines therein being moved to other running physical machines, and then shut off. The resource allocation process is conducted to distribute loads of the running physical machines such that the total numbers of the running physical machines are capable of being dispatched flexibly to achieve the object of green power management.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: June 3, 2014
    Assignee: Tunghai University
    Inventors: Chao-Tung Yang, Hsiang-Yao Cheng, Kuan-Chieh Wang
  • Patent number: D841186
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: February 19, 2019
    Assignee: TUNGHAI UNIVERSITY
    Inventor: Wei-Ting Chao