Abstract: A disease management method and apparatuses performing the disease management method are disclosed. The disease management method may include receiving bioinformation of a cow from a biosensor capsule provided in a stomach of the cow, determining a health state of the cow by analyzing the received bioinformation, and transmitting information associated with the determined health state to a user who manages the cow, in which the health state may include at least one of a breeding-related state associated with estrus and delivery of the cow, a disease state of the cow, a methane gas generation state of the cow, or a rumen activity state of the cow.