Patents Assigned to Unhwa Corporation
  • Patent number: 9585923
    Abstract: The present invention relates to an antioxidant, anti-inflammatory or anti-aging composition containing any one or more of a Taxus cambium- or procambium-derived cell line, an extract thereof, a lysate thereof and a culture medium thereof. The composition according to the present invention has minimized side effects compared to existing antioxidants and anti-inflammatory agents, is involved in intracellular metabolism to reduce intracellular reactive oxygen species, and reduces and induces aging-related signals. Thus, the composition of the preset invention is useful for preventing and delaying aging. In addition, the composition of the present invention has the effect of inhibiting melanogenesis, and thus is useful as a whitening cosmetic composition.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: March 7, 2017
    Assignee: UNHWA CORPORATION
    Inventors: Dae Hee Lee, Eun Kyong Lee, Eun Mi So, Young Woo Jin
  • Patent number: 9415081
    Abstract: The present invention relates to a composition for preventing or treating acquired immunodeficiency syndrome (AIDS), comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof, which are derived from a natural product, minimize adverse side effects of prior therapeutic agents and safe for the human body. Further, they effectively increase the count of T cells such as CD4+ T cells and decrease the number of HIVs, thereby preventing opportunistic infection, dysneuria, and neoplaia caused by immune incompetence, and ultimately the risk of death. Therefore, they are useful in preventing and treating AIDS, and relieving symptoms of AIDS.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 16, 2016
    Assignees: UNHWA CORPORATION
    Inventors: Sun Mi Hong, Eun Kyong Lee, Young Woo Jin
  • Patent number: 9314492
    Abstract: The present invention relates to a composition for preventing or treating cancer, which contains, as an active ingredient, a Panax ginseng cambium-derived cell line including wild ginseng or ginseng; a lysate thereof; an extract thereof; or a culture medium thereof, which are derived from a natural and have minimized side effects compared to the conventional therapeutic drugs, and thus are safe for the human body. Also, they are involved directly in the growth of cancer to induce cancer cell death effectively, and show anticancer activity of inhibiting or reducing the formation of tumor or the growth of tumor.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: April 19, 2016
    Assignees: UNHWA CORPORATION
    Inventors: Young Woo Jin, Eun Kyong Lee
  • Patent number: 9095532
    Abstract: The present invention relates to an anti-aging or antioxidant composition which contains, as an active ingredient, a plant stem cell line derived from the cambium of Panax ginseng, including wild ginseng and ginseng, or an extract thereof, a lysate thereof and a culture thereof. The composition has minimized side effects compared to existing anti-aging agents and antioxidants, and thus is safe for the skin. Also, the composition of the present invention shows an antioxidant effect of inhibiting reactive oxygen species caused by exposure to UV radiation that is the major cause of skin aging, and it can effectively reduce or inhibit aging-related factors. Thus, the composition is useful for the prevention and inhibition of aging.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: August 4, 2015
    Assignees: Unhwa Corporation
    Inventors: Mi Ok Jang, Min Jung Lim, Il Seok Oh, Dae Hee Lee, Eun Kyong Lee, Young Woo Jin
  • Patent number: 8790927
    Abstract: The present invention relates to a composition for preventing or treating cancer, which contains, as an active ingredient, a Taxus cambium- or procambium-derived cell line; a lysate thereof; an extract thereof; or a culture medium thereof. The cell line, the lysate, the extract, and the culture medium has minimized side effects compared to the conventional therapeutic drugs, is safe to the human body, is involved directly in the growth of cancer to induce cancer cell death, and shows anticancer activity of inhibiting angiogenesis occurring in carcinogenesis. Accordingly, the cell line, the lysate, the extract and the culture medium is useful for the prevention, treatment and alleviation of cancer.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: July 29, 2014
    Assignee: Unhwa Corporation
    Inventors: Joong Hyun Park, Min Jung Lim, Il Seok Oh, Dae Hee Lee, Jung Chang Lee, Eun Kyong Lee, Young Woo Jin
  • Publication number: 20140099285
    Abstract: The present invention relates to a composition for preventing or treating acquired immunodeficiency syndrome (AIDS), comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof, which are derived from a natural product, minimize adverse side effects of prior therapeutic agents and safe for the human body. Further, they effectively increase the count of T cells such as CD4+ T cells and decrease the number of HIVs, thereby preventing opportunistic infection, dysneuria, and neoplaia caused by immune incompetence, and ultimately the risk of death. Therefore, they are useful in preventing and treating AIDS, and relieving symptoms of AIDS.
    Type: Application
    Filed: March 14, 2013
    Publication date: April 10, 2014
    Applicant: UNHWA CORPORATION
    Inventor: UNHWA CORPORATION
  • Patent number: 8617621
    Abstract: The present invention relates to a composition for enhancing immunity, comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture medium thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof according to the present invention, which are derived from a natural product, minimize adverse side effects of prior immune enhancing agents and safe for the human body. Further, they effectively increase the activity of NK cells responsible for innate immunity, as well as increase the proliferation rate of lymph node cells when the cells were re-exposed to an antigen in a specific immune reaction to enhance acquired immunity, and thus are useful as an immune enhancing agent.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: December 31, 2013
    Assignees: Unhwa Corporation
    Inventors: Min Jung Lim, Young Woo Jin, Eun Kyong Lee
  • Publication number: 20130315877
    Abstract: The present invention relates to a composition for preventing or treating cancer, which contains, as an active ingredient, a Taxus cambium- or procambium-derived cell line; a lysate thereof; an extract thereof; or a culture medium thereof. The cell line, the lysate, the extract, and the culture medium has minimized side effects compared to the conventional therapeutic drugs, is safe to the human body, is involved directly in the growth of cancer to induce cancer cell death, and shows anticancer activity of inhibiting angiogenesis occurring in carcinogenesis. Accordingly, the cell line, the lysate, the extract and the culture medium is useful for the prevention, treatment and alleviation of cancer.
    Type: Application
    Filed: January 31, 2013
    Publication date: November 28, 2013
    Applicant: UNHWA CORPORATION
    Inventor: UNHWA CORPORATION
  • Publication number: 20130202631
    Abstract: The present invention relates to a composition for preventing or treating liver diseases, which contains, as an active ingredient, any one or more of a homogeneous cell line derived from the cambium of Panax ginseng, including wild ginseng or ginseng, a lysate thereof, an extract thereof and a culture medium thereof. The homogeneous cell line according to the present invention, a lysate thereof, an extract thereof and a culture medium thereof have minimized side effects compared to existing agents for treating liver diseases, and thus are safe for the human body. Also, they can increase the levels of s-antibody (HBsAb) and e-antibody (HBeAb) against hepatitis virus and inhibit the proliferation of hepatitis virus, and thus they are useful for the prevention and treatment of liver diseases. In addition, they have the effect of lowering the levels of liver injury, and thus are useful as a functional food for improving liver function.
    Type: Application
    Filed: April 16, 2013
    Publication date: August 8, 2013
    Applicant: UNHWA Corporation
    Inventor: UNHWA Corporation
  • Publication number: 20130137178
    Abstract: The present invention relates to a cell line derived from the cambium of an herbaceous plant having a storage root and a method for isolating the same. More specifically, relates to a cambium-derived homogeneous cell line having the ability to divide, which is obtained from the cambium-containing storage tissue of an herbaceous plant having a storage root without a separate dedifferentiation process, and to a method for isolating the same. The cell line derived from the cambium of an herbaceous plant having a storage root has an active division ability and is homogeneous. Also, it is stable during culture, because it has not undergone a dedifferentiation process. Thus, through the optimization of proliferation thereof, the cell line can be allowed to proliferate in a large amount within a short time.
    Type: Application
    Filed: July 17, 2012
    Publication date: May 30, 2013
    Applicant: Unhwa Corporation
    Inventors: Mi Ok Jang, Eun Kyong Lee, Young Woo Jin
  • Patent number: 8329471
    Abstract: This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from cambium or procambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: December 11, 2012
    Assignee: Unhwa Corporation
    Inventors: Young Woo Jin, Eun Kyong Lee
  • Patent number: 8247230
    Abstract: The present invention relates to a cell line derived from the cambium of an herbaceous plant having a storage root and a method for isolating the same. More specifically, relates to a cambium-derived homogeneous cell line having the ability to divide, which is obtained from the cambium-containing storage tissue of an herbaceous plant having a storage root without a separate dedifferentiation process, and to a method for isolating the same. The cell line derived from the cambium of an herbaceous plant having a storage root has active division ability and is homogeneous. Also, it is stable during culture, because it has not undergone a dedifferentiation process. Thus, through the optimization of proliferation thereof, the cell line can be allowed to proliferate in a large amount within a short time.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: August 21, 2012
    Assignee: Unhwa Corporation
    Inventors: Mi Ok Jang, Eun Kyong Lee, Young Woo Jin
  • Publication number: 20120039918
    Abstract: The present invention relates to a composition for enhancing immunity, comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture medium thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof according to the present invention, which are derived from a natural product, minimize adverse side effects of prior immune enhancing agents and safe for the human body. Further, they effectively increase the activity of NK cells responsible for innate immunity, as well as increase the proliferation rate of lymph node cells when the cells were re-exposed to an antigen in a specific immune reaction to enhance acquired immunity, and thus are useful as an immune enhancing agent.
    Type: Application
    Filed: February 23, 2010
    Publication date: February 16, 2012
    Applicant: Unhwa Corporation
    Inventors: Min Jung Lim, Young Woo Jin, Eun Kyong Lee
  • Patent number: 8053238
    Abstract: This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from the procambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: November 8, 2011
    Assignee: Unhwa Corporation
    Inventors: Young Woo Jin, Eun Kyong Lee
  • Publication number: 20110229443
    Abstract: The present invention relates to a composition for preventing or treating cancer, which contains, as an active ingredient, a Panax ginseng cambium-derived cell line including wild ginseng or ginseng; a lysate thereof; an extract thereof; or a culture medium thereof. The cell line according to the present invention, a lysate thereof, an extract thereof and a culture medium thereof are derived from a natural and have minimized side effects compared to the conventional therapeutic drugs, and thus are safe for the human body. Also, they are involved directly in the growth of cancer to induce cancer cell death effectively, and show anticancer activity of inhibiting or reducing the formation of tumor or the growth of tumor, Accordingly, the cell line, the lysate thereof, the extract thereof and the culture medium thereof are useful for the prevention, treatment and alleviation of cancer.
    Type: Application
    Filed: November 6, 2009
    Publication date: September 22, 2011
    Applicant: Unhwa Corporation
    Inventors: Young Woo Jin, Eun Kyong Lee
  • Patent number: 8017397
    Abstract: This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from the cambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: September 13, 2011
    Assignee: Unhwa Corporation
    Inventors: Young Woo Jin, Eun Kyong Lee
  • Publication number: 20110217273
    Abstract: The present invention relates to a composition for preventing or treating acquired immunodeficiency syndrome (AIDS), comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof, which are derived from a natural product, minimize adverse side effects of prior therapeutic agents and safe for the human body. Further, they effectively increase the count of T cells such as CD4+ T cells and decrease the number of HIVs, thereby preventing opportunistic infection, dysneuria, and neoplasia caused by immune incompetence, and ultimately the risk of death. Therefore, they are useful in preventing and treating AIDS, and relieving symptoms of AIDS.
    Type: Application
    Filed: September 30, 2009
    Publication date: September 8, 2011
    Applicant: Unhwa Corporation
    Inventors: Sun Mi Hong, Eun Kyong Lee, Young Woo Jin
  • Publication number: 20110117039
    Abstract: The present invention relates to an antioxidant, anti-inflammatory or anti-aging composition containing any one or more of a Taxus cambium- or procambium-derived cell line, an extract thereof, a lysate thereof and a culture medium thereof. The composition according to the present invention has minimized side effects compared to existing antioxidants and anti-inflammatory agents, is involved in intracellular metabolism to reduce intracellular reactive oxygen species, and reduces and induces aging-related signals. Thus, the composition of the preset invention is useful for preventing and delaying aging. In addition, the composition of the present invention has the effect of inhibiting melanogenesis, and thus is useful as a whitening cosmetic composition.
    Type: Application
    Filed: May 14, 2009
    Publication date: May 19, 2011
    Applicant: UNHWA CORPORATION
    Inventors: Dae Hee Lee, Eun Kyong Lee, Eun Mi So, Young Woo Jin
  • Publication number: 20110097310
    Abstract: The present invention relates to an anti-aging or antioxidant composition which contains, as an active ingredient, a plant stem cell line derived from the cambium of Panax ginseng, including wild ginseng and ginseng, or an extract thereof, a lysate thereof and a culture thereof. The composition has minimized side effects compared to existing anti-aging agents and antioxidants, and thus is safe for the skin. Also, the composition of the present invention shows an antioxidant effect of inhibiting reactive oxygen species caused by exposure to UV radiation that is the major cause of skin aging, and it can effectively reduce or inhibit aging-related factors. Thus, the composition is useful for the prevention and inhibition of aging.
    Type: Application
    Filed: June 12, 2009
    Publication date: April 28, 2011
    Applicant: UNHWA CORPORATION
    Inventors: Mi Ok Jang, Min Jung Lim, Il Seok Oh, Dae Hee Lee, Eun Kyong Lee, Young Woo Jin
  • Publication number: 20100272692
    Abstract: The present invention relates to a composition for preventing or treating cancer, which contains, as an active ingredient, a Taxus cambium- or procambium-derived cell line; a lysate thereof; an extract thereof; or a culture medium thereof. The cell line, the lysate, the extract, and the culture medium has minimized side effects compared to the conventional therapeutic drugs, is safe to the human body, is involved directly in the growth of cancer to induce cancer cell death, and shows anticancer activity of inhibiting angiogenesis occurring in carcinogenesis. Accordingly, the cell line, the lysate, the extract and the culture medium is useful for the prevention, treatment and alleviation of cancer.
    Type: Application
    Filed: October 10, 2008
    Publication date: October 28, 2010
    Applicant: UNHWA CORPORATION
    Inventors: Joong Hyun Park, Min Jung Lim, Il Seok Oh, Dae Hee Lee, Jung Chang Lee, Eun Kyong Lee, Young Woo Jin