Abstract: A compound, and a pharmaceutical composition comprising an effective mount to treat HBV or EBV of a compound, of the formula: ##STR1## wherein R is selected from the group consisting of 5-methyluracil, adenine and cytosine, and R' is hydrogen, acyl, or alkyl or a monophosphate, diphosphate or triphosphate ester, or its pharmaceutically acceptable salt.
Type:
Grant
Filed:
January 28, 1994
Date of Patent:
December 24, 1996
Assignees:
Univ. of GA Research Foundation, Yale University
Inventors:
Chung K. Chu, Yung-Chi Cheng, Balakrishna S. Pai, Gang-Qing Yao
Abstract: A method for the treatment of a human infected with HBV that includes administering an HBV-treatment amount of an L-nucleoside of the formula: ##STR1## wherein R is selected from the group consisting of 5-methyluracil, adenine and cytosine, and R' is hydrogen, acyl, alkyl or a monophosphate, diphosphate or triphosphate ester, or its pharmaceutically acceptable salt.
Type:
Grant
Filed:
June 6, 1995
Date of Patent:
October 22, 1996
Assignees:
Univ. of GA Research Foundation, Yale University
Inventors:
Chung K. Chu, Yung-Chi Cheng, Balakrishna S. Pai, Gang-Oing Yao