Abstract: The invention relates to a reaction vessel and a reaction controller, wherein temperature control of a liquid stored within the vessel can be performed with a high accuracy and faithful responsiveness. The reaction container and the reaction controller comprise one or a plurality of reaction chambers in which liquid is storable, and a wall that surrounds the reaction chamber, and the entirety or a part of the wall is formed by a temperature raising and lowering body that can raise or lower the temperature thereof according to a signal from an instructing part provided outside.
Abstract: A biological material fixed region enclosing tip, a biological material fixed region treatment apparatus, and a treatment method thereof. The biological material fixed region enclosing tip comprises: a tip form vessel having an installation opening part that is installable to a nozzle that performs suction and discharge of gas, and an opening through which inflow and outflow of fluid is possible by means of the suction and discharge of gas; a fixing region provided in the tip form vessel, in which a predetermined biological material is fixed or fixable in a plurality of different positions that are determined beforehand that are distinguishable from the exterior; and an enclosing section that encloses the fixing region within the tip form vessel such that the fixing region is able to make contact in an immovable state with the fluid that has flown into the tip form vessel from the opening.
Abstract: The present invention relates to a temperature controlling apparatus and the temperature controlling method which can arrest foaming and inflation of the air contained in a liquid, and can perform temperature controlling of a liquid of high reliance, and the present invention is constructed to have one or a plurality of sets of nozzles which can suck and discharge a liquid through a tip, and can retain the sucked liquid, a suction and discharge mechanism which can suck and discharge a gas via the each nozzle, a temperature regulator which can maintain one or two or more set predetermined temperatures for a predetermined time regarding one or two or more predetermined temperature controlling regions set in the each nozzle, a movement mechanism which allows relative movement between one or two or more containers which can accommodate a liquid and a nozzle, and a controlling part which instructs the movement mechanism, the suction and discharge mechanism or the temperature regulator to adjust a liquid to be suck
Abstract: The invention relates to a material for capturing microbes or the like, a device for capturing microbes or the like, a method of capturing microbes or the like, and a method of producing a material for capturing microbes or the like, and has an object of using a pulverizable resin whereby a minor amount of microbes or the like contained in a large amount of a liquid, or microbes or the like contained in a small amount of a liquid can be captured efficiently, quickly, labor-savingly, and reliably. Disclosed is: a material for capturing microbes or the like, which comprises irregular-shaped powdery grains made of a pulverizable adsorbent resin and distributed in a predetermined grain size range, and which can adsorb or bond to a target such as a microbe contained in a liquid; a device for capturing microbes or the like; and a method of capturing microbes or the like.
Abstract: The present invention relates to a filtration method, a filter-incorporated tip and a filtration device, and its object is to perform efficient and swift isolation of a target substance.
Abstract: The present invention relates to a column tip processing device and a column tip processing method, and its objective is to enhance the contact between a packing and a fluid as a subject to be processed whereby accomplishing a highly efficient reaction as well as an accurate processing, which has a nozzle head having a single or multiple-channeled nozzle, a suction and discharge mechanism, one or more types of column tips in which a packing is enclosed, a stage provided with a fluid housing part group including a plurality of fluid housing parts in which various solutions are or can be housed, and moving means for moving the nozzle head relatively to the fluid housing part group, and also has a controlling part which controls the suction and discharge mechanism and the moving means with regard to quantities, pressure, flow rate, the number of cycles, time or position of the suction or discharge by the nozzle based on a structural requirement relating to the structure of the one or more types of column tips to
Abstract: The present invention provides a composition capable of hermetically sealing a PCR reaction vessel without using a closure member or adhesive seal. Disclosed is a composition for preventing evaporation of a nucleic acid amplification reaction solution during nucleic acid amplification reaction, which is a liquid during the reaction and becomes a solid through chemical or thermal changes after completion of the reaction. Also disclosed is a composition for preventing evaporation of a nucleic acid amplification reaction solution during nucleic acid amplification reaction, wherein the melting point of the composition is 0-15° C. Also disclosed is a composition for preventing evaporation of a nucleic acid amplification reaction solution during nucleic acid amplification reaction, wherein the melting point of the composition is 5-10° C.
Abstract: A biological material fixed carrier enclosing tip, a biological material fixed carrier treatment apparatus, and a treatment method thereof. An object is to obviate attachment control and suction control for storing and retaining the carrier in the tip form vessel, to simplify complex reaction processes, and to make processing of the biological material fixed carrier to be easily executed as a result of a small-scale device configuration. The biological material fixed carrier enclosing tip comprises: a tip form vessel having an installation opening part that is installable to a nozzle, and a narrow tube that possesses an opening, through which fluid inflow and outflow is possible, that is narrower than the nozzle; a carrier in which a predetermined biological material is fixed or fixable, and has a size or a shape that is able to pass through the opening; and an enclosing section provided on the tip form vessel.
Abstract: The present invention relates to a magnetic reagent, a magnetic reagent kit, a method for treating magnetic carriers, and a treatment device therefor, with an object of quickly and efficiently treating magnetic carriers of a micro particle diameter including nanosized magnetic carriers. The magnetic reagent or magnetic reagent kit includes: a plurality of magnetic carriers which can be magnetized by being exposed to a magnetic field, can be bonded to a predetermined chemical substance or living organism in a liquid, and that have a particle diameter that enables them to be suspended in the liquid; and a plurality of treatment promoting magnetic particles which can be magnetized by being exposed to a magnetic field and thus can have the magnetic carriers adsorbed on the surface thereof, are formed so that they can be moved within the liquid by movement of the liquid or by a magnetic field, and promote a treatment for capturing or re-suspension of the magnetic carriers.
Abstract: The present invention relates to a pipette tip having a support and a fluid enclosed therein, an apparatus for treating the pipette tip having a support and a fluid enclosed therein, and a method of treating the pipette tip having a support and a fluid enclosed therein.
Abstract: There are provided a method of detecting dispensed quantity in which without the need of detecting a surface of liquid accommodated in a container, a liquid quantity can be detected only by measuring pressure change; and a relevant liquid suction monitoring dispensing apparatus.
Abstract: A various-substance holder, a various-substance holder treating apparatus, and a various-substance holder treating method are provided which enable the mutual identification of particulate carriers to which various substances are or can be immobilized without the need to arrange the particulate carriers at predetermined positions or in a predetermined order, eliminating the need for time and effort to arrange the various substances at predetermined positions or in a predetermined order to allow treatments to be quickly and easily achieved. The various-substance holder has a plurality of particulate carriers or plural sets of particulate carriers to which plural types of chemical substances are or can be immobilized and a carrier holding portion holding the plurality of particulate carriers or the plural sets of particulate carriers in a substantially stationary state such that the plurality of particulate carriers or the plural sets of particulate carriers can be externally measured.
Abstract: A biological material fixed carrier enclosing tip, a biological material fixed carrier treatment apparatus, and a treatment method thereof. An object is to obviate attachment control and suction control for storing and retaining the carrier in the tip form vessel, to simplify complex reaction processes, and to make processing of the biological material fixed carrier to be easily executed as a result of a small-scale device configuration.
Abstract: A biological material fixed region enclosing tip, a biological material fixed region treatment apparatus, and a treatment method thereof. The biological material fixed region enclosing tip comprises: a tip form vessel having an installation opening part that is installable to a nozzle that performs suction and discharge of gas, and an opening through which inflow and outflow of fluid is possible by means of the suction and discharge of gas; a fixing region provided in the tip form vessel, in which a predetermined biological material is fixed or fixable in a plurality of different positions that are determined beforehand that are distinguishable from the exterior; and an enclosing section that encloses the fixing region within the tip form vessel such that the fixing region is able to make contact in an immovable state with the fluid that has flown into the tip form vessel from the opening.
Abstract: It is an object of this invention to provide a sample integration cassette, a spotting device and a sample integration device which enhance a sample integration density and reduce the size of a sample assembly and a probe. The sample integration cassette has the sample assembly and the sample support carrier so arranged therein that the sample support can be fed from the sample support carrier onto the sample assembly at a predetermined angle to the sample assembly at all times. The cassette is formed so as to be connectable with a drive unit that applies a drive force to the sample assembly and the sample support carrier interlockingly and synchronously. The spotting device has a delivery member mounting table which is vertically moved over the sample support carrier to apply samples to the sample support from the delivery member.
Type:
Grant
Filed:
April 20, 2005
Date of Patent:
May 1, 2012
Assignee:
Universal Bio Research Co., Ltd.
Inventors:
Hideji Tajima, Tsutomu Asano, Junko Asahina, Mamiko Yoshida
Abstract: To provide a magnetic particle parallel processing apparatus permitting repeated use of a container, and a method of magnetic particle parallel processing permitting repeated use of a container, with which the rate of repeated use of a container is enhanced to thereby achieve a saving in the working space and a saving in the working time. The apparatus comprises: at least one reaction container; a liquid disposal tank; a reagent etc.
Abstract: A bio-related substance assay tube 2 comprises a target substance capture bead 3 serving as a first microparticle, compensation bead 4 serving as a second microparticle on which a given amount of a bio-related substance has been immobilized, and a negative control bead 5 serving as a third microparticle for use as a negative control. A mount unit 12 comprises a nozzle communicating with a pump, and the bio-related substance assay tube 2 is mounted in the mount unit 12 to ensure communication with this nozzle. An analyte is introduced into the bio-related substance assay tube 2, followed by labeling the bio-related substance bound to each microparticle to cause light emission. Based on light emission from each microparticle, a calibration curve is prepared or the emission intensity of the first microparticle is compensated to quantify the bio-related substance.
Abstract: A biological material fixed region enclosing tip, a biological material fixed region treatment apparatus, and a treatment method thereof. An object is to enable processing to be performed while a fixing region is enclosed in an immovable state with respect to the tip form vessel, and to execute processing of high reliability with a simple apparatus.