Patents Assigned to Universidade de Sao Paulo
  • Publication number: 20230399261
    Abstract: A polypropylene fiber including: a polypropylene matrix, at least a surface modifier, and at least an additive selected from surfactants, lubricating agents or mixtures thereof. A method of producing polypropylene fibers by (i) mixing a polypropylene with a surface modifier in extrusion, (ii) melt spinning the composition obtained in step (i) to produce the fibers, where a surfactant is added to step (i) and/or a lubricant is applied to the fibers during step (ii). A fiber cement-reinforced composite including a cementitious matrix, a cellulosic component, optionally, a limestone component and a polypropylene fiber comprising: a polypropylene matrix, at least a surface modifier, at least one additive selected from surfactants, lubricating agents and mixtures thereof. An article comprising the fiber cement-reinforced composite and a roof tile comprising the fiber cement-reinforced composite.
    Type: Application
    Filed: June 9, 2023
    Publication date: December 14, 2023
    Applicants: Braskem S.A., UNIVERSIDADE DE SÃO PAULO
    Inventors: Mauro Alfredo Soto Oviedo, Holmer Savastano Junior, Ronaldo Soares Teixeira
  • Publication number: 20230303437
    Abstract: The present disclosure relates to the field of building materials. In particular, the present disclosure relates to fiber cement production methods and processes that exhibit high solid retention capacity in the dewatering step, providing increased productivity and potentially other process gains related to the lower concentration of solids and additives in the process water.
    Type: Application
    Filed: August 17, 2021
    Publication date: September 28, 2023
    Applicants: SUZANO, S.A., UNIVERSIDADE DE SÃO PAULO-USP
    Inventors: Germano SIQUEIRA, Vanderley Moacyr JOHN, Beatriz Rodrigues DA SILVA, Fábio Alonso CARDOSO, Holmer Savastano JUNIOR
  • Patent number: 11389423
    Abstract: A pharmaceutical composition containing synthetic Cannabidiol and its use in obtaining a medication for the treatment of neurological disorders, as well as the main excipients used in the production process, in addition to its small, medium, and large-scale preparation process. The use of the composition for the treatment of neurological disorders in human or animal populations, in particular in the treatment of Parkinson's disease, in the range of 300 to 850 mg/day or at daily doses of 100 to 1750 mg for neuroprotective action.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: July 19, 2022
    Assignees: Prati, Donaduzzi & Cia Ltda, Universidade De São Paulo
    Inventors: Luiz Donaduzzi, Carmen Maria Donaduzzi, Liberato Brum Junior, Patricia Moura Da Rosa Zimmerman, Emanuelle Webler, Leticia Mello Rechia, José Alexandre Crippa, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, Francisco Silveira Guimarães, Alline Cristina De Campos, Vitor Tumas, Elaine Aparecida Del Bel Belluz Guimarães
  • Patent number: 11284883
    Abstract: Surgical instruments for surgical suturing, for the purpose of enabling direct vision access, abdominal wall suturing and procedures of minimum invasion of abdominal structure from the surface thereof to deeper layers.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: March 29, 2022
    Assignee: HOSPITAL DAS CLINICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SÄO PAULO-HCFMUSP
    Inventors: Ricardo Abdalla, Helio Ozawa
  • Patent number: 10972259
    Abstract: A method for computing a shared key (K) for encrypting data between a first device and a second device. The method includes communicating a first private ephemeral key (XA), and a first parameter set (YA) to a second device. The first parameter set (YA) includes identity data (IDA) that identifies the first device, a random point (VA) on an elliptic curve, and a first public key (UA). The first device receives a second private ephemeral key (XB) and a second parameter set (YB). The second parameter set (YB) includes identity data (IDB) that identifies the second device, a random point (VB) on the elliptic curve, and a second public key (UB). Verifying operations are performed to verify the second public key (UB) and the second private ephemeral key (XB) as valid. A shared key (K) is then computed based at least on the first parameter set (YA), the second parameter set (YB), the first private ephemeral key (XA), and the second private ephemeral key (XB).
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: April 6, 2021
    Assignees: LG ELECTRONICS INC., UNIVERSIDADE DE SAO PAULO
    Inventors: Marcos A. Simplicio, Jr., Marcos V. M. Silva, Renan C. A. Alves
  • Publication number: 20200368197
    Abstract: A pharmaceutical composition containing synthetic Cannabidiol and its use in obtaining a medication for the treatment of neurological disorders, as well as the main excipients used in the production process, in addition to its small, medium, and large-scale preparation process. The use of the composition for the treatment of neurological disorders in human or animal populations, in particular in the treatment of Parkinson's disease, in the range of 300 to 850 mg/day or at daily doses of 100 to 1750 mg for neuroprotective action.
    Type: Application
    Filed: February 11, 2019
    Publication date: November 26, 2020
    Applicants: Prati, Donaduzzi & Cia Ltda, Universidade De São Paulo
    Inventors: Luiz Donaduzzi, Carmen Maria Donaduzzi, Liberato Brum Junior, Patrícia Moura Da Rosa Zimmerman, Emanuelle Webler, Letícia Mello Rechia, José Alexandre Crippa, Jaime Eduardo Cecilio Hallak, Antonio Waldo Zuardi, Francisco Silveira Guimarães, Alline Cristina De Campos, Vitor Tumas, Elaine Aparecida Del Bel Belluz Guimarães
  • Publication number: 20190215154
    Abstract: A method for computing a shared key (K) for encrypting data between a first device and a second device. The method includes communicating a first private ephemeral key (XA), and a first parameter set (YA) to a second device. The first parameter set (YA) includes identity data (IDA) that identifies the first device, a random point (VA) on an elliptic curve, and a first public key (UA). The first device receives a second private ephemeral key (XB) and a second parameter set (YB). The second parameter set (YB) includes identity data (IDB) that identifies the second device, a random point (VB) on the elliptic curve, and a second public key (UB). Verifying operations are performed to verify the second public key (UB) and the second private ephemeral key (XB) as valid. A shared key (K) is then computed based at least on the first parameter set (YA), the second parameter set (YB), the first private ephemeral key (XA), and the second private ephemeral key (XB).
    Type: Application
    Filed: September 5, 2017
    Publication date: July 11, 2019
    Applicants: LG ELECTRONICS INC., UNIVERSIDADE DE SAO PAULO
    Inventors: Marcos A. SIMPLICIO JR., Marcos V. M. SILVA, Renan C. A. ALVES
  • Patent number: 10086358
    Abstract: The present invention lies in the fields of chemistry and nanotechnology and describes a nanocomposite to be used in the recovery of several compounds from inorganic or organic medium. Specifically, the invention presents a nanocomposite consisting of magnetic nanoparticles composed of Fe3O4 associated to an activated charcoal adsorbent substrate, a process to obtain and methods of use of the nanocomposite. The present invention enables the processing, concentration and recovery of large volumes of contaminated water, regenerating magnetic adsorbent material for reuse, in a cyclic and sustainable manner, transforming dispersed/diluted pollutants in pre-concentrates that can be easily processed, helping to conserve natural resources.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: October 2, 2018
    Assignees: PETROLEO BRASILEIRO S.A.-PETROBRAS, Universidade de Sao Paulo-USP
    Inventors: Koiti Araki, Ulisses Condomitti Epamino, Alceu Totti Silveira Junior, Sergio Hiroshi Toma, Henrique Eisi Toma
  • Publication number: 20180264121
    Abstract: The present invention describes an oral pharmaceutical composition comprising cannabinoid(s), an oily liquid solvent and a co-solvent, as well as a process for preparing and the same for the treatment of neurological disorders, especially refractory epilepsy. The analytical methods used to ensure identity, quality and purity of Active Pharmaceutical Ingredient and formulation produced were validated and have defined specifications.
    Type: Application
    Filed: September 16, 2016
    Publication date: September 20, 2018
    Applicants: PRATI-DONADUZZI & CIA LTDA., UNIVERSIDADE DE SÃO PAULO
    Inventors: Luiz DONADUZZI, Carmen Maria DONADUZZI, Christian Gregory Burgos DE MENEZES, Liberato Brum JUNIOR, Volnei José Tondo FILHO, Patricia Moura ROSA, José Alexandre CRIPPA, Jaime Eduardo Cecilio HALLAK, Antonio Waldo ZUARDI, Francisco Silveira GUIMARÃES
  • Patent number: 9653773
    Abstract: The instant disclosure describes a radiofrequency propagation line including a conducting strip connected to a conducting plane parallel to the plane of the conducting strip, wherein the conducting plane includes a network of nanowires made of an electrically conductive, non-magnetic material extending orthogonally to the plane of the conducting strip, in the direction of said conducting strip.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: May 16, 2017
    Assignees: UNIVERSITE GRENOBLE ALPES, INSTITUTE POLYTECHNIQUE DE GRENOBLE, UNIVERSIDADE DE SAO PAULO USP
    Inventors: Philippe Ferrari, Gustavo Pamplona Rehder, Ariana Serrano, Florence Podevin, Anne-Laure Franc
  • Patent number: 9637533
    Abstract: The present invention relates to a method for increasing embryo implantation rate in mother's uterus in mammals by administering to the uterus of a mammal an effective amount of beta-galactoside-binding lectin or derivatives thereof, as well as to a product comprising said lectin.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: May 2, 2017
    Assignees: UNIVERSIDADE DE SÃO PAULO-USP, INPRENHA BIOTECHNOLOGIA E DESENVOLVIMENTO AVANçADO LTDA-ME
    Inventors: Marcelo Dias Baruffi, Erika da Silva Carvalho Morani, Marcelo Roncoletta, Camillo del Cistia Andrade, Lilian Cataldi Rodrigues
  • Patent number: 9447019
    Abstract: The present invention relates to fluorine substituted CBD compounds, compositions thereof and uses thereof for the preparation of medicaments.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: September 20, 2016
    Assignees: UNIVERSIDADE DE SAO PAULO-USP, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL-UFRGS, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventors: Raphael Mechoulam, Antonio Waldo Zuardi, Flavio Pereira Kapczinski, Jaime Eduardo Cecilio Hallak, Francisco Silveira Guimaraes, Jose Alexandre de Souza Crippa, Aviva Breuer
  • Publication number: 20160251561
    Abstract: This invention describes the development of technology for the preparation of superparamagnetic lipophilic nanofluids, as well as of drilling fluid additives based on the aforementioned nanofluids, which improve the properties which form walls or mud filter cakes and concomitantly act as contrast agents in RMN logging.
    Type: Application
    Filed: February 25, 2016
    Publication date: September 1, 2016
    Applicants: PETRÓLEO BRASILEIRO S.A. - PETROBRAS, Universidade de Sao Paulo - USP
    Inventors: Koiti ARAKI, Sergio Hiroshi TOMA, Delmárcio Gomes DA SILVA, Henrique Eisi TOMA, Rita de Cássia Comis WAGNER, Bernardo Coutinho Camilo DOS SANTOS, Alex Tadeu de Almeida WALDMANN
  • Publication number: 20160074320
    Abstract: The present invention relates to pharmaceutical compositions comprising a peptide that stimulates the release of gonadotropins and sexual steroids. More specifically, the present invention provides pharmaceutical compositions comprising kisspeptin, preferably in the kp-10 form, or derivatives thereof, for use in ovulation cycle inducing and/or infertility treatment programs. The formulations according to the present invention belong to two main groups: injectable solutions and implantable formulations. The injectable solutions according to the present invention can be divided into immediate release solutions and prolonged action solutions. The implantable formulations according to the present invention can be prepared using an RTV silicone elastomer, a rapid vulcanization silicone elastomer or a rapid vulcanization silicone elastomer with a release modulator.
    Type: Application
    Filed: April 9, 2014
    Publication date: March 17, 2016
    Applicants: UNIVERSIDADE DE SAO PAULO - USP, OURO FINO SAUDE ANIMAL LTDA
    Inventors: Dolivar Coraucci NETO, Gustavo Guerino MACEDO, Pietro Sampaio BARUSELLI
  • Publication number: 20150367324
    Abstract: The present invention lies in the fields of chemistry and nanotechnology and describes a nanocomposite to be used in the recovery of several compounds from inorganic or organic medium. Specifically, the invention presents a nanocomposite consisting of magnetic nanoparticles composed of Fe3O4 associated to an activated charcoal adsorbent substrate, a process to obtain and methods of use of the nanocomposite. The present invention enables the processing, concentration and recovery of large volumes of contaminated water, regenerating magnetic adsorbent material for reuse, in a cyclic and sustainable manner, transforming dispersed/diluted pollutants in pre-concentrates that can be easily processed, helping to conserve natural resources.
    Type: Application
    Filed: June 11, 2015
    Publication date: December 24, 2015
    Applicants: Universidade de Sao Paulo-USP, PETROLEO BRASILEIRO S.A. - PETROBRAS
    Inventors: Koiti ARAKI, Ulisses Condomitti EPAMINO, Alceu Totti SILVEIRA JUNIOR, Sergio Hiroshi TOMA, Henrique Eisi TOMA
  • Patent number: 9090702
    Abstract: Modern sugarcane cultivars are complex hybrids resulting from crosses among several species of the Saccharum genus. Traditional breeding methods have been extensively employed in different countries along the past decades to develop varieties with increased sucrose yield, and resistant to plagues and diseases. Conventional varietal improvement is, however, limited by the narrow pool of suitable markers. In this sense, molecular genetics is seen as a promising tool to assist in the process of molecular marker identification. The present invention concerns the identification of 348 genes associated with sucrose content in sugarcane plants. The genes were found to be differentially expressed when high sucrose and low sucrose plants and populations of plants were compared and/or when high and low sucrose internodes were compared. The expression data was obtained using cDNA microarray and quantitative PCR technologies.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: July 28, 2015
    Assignees: UNIVERSIDADE DE SAO PAULO-USP., UNIVERSIDADE ESTADUAL DE CAMPINAS-UNICAMP., FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO-FAPESP., CENTRO DE TECNOLOGIA CANAVIEIRA, CENTRAL DE ALCOOL LUCELIA LTDA.
    Inventors: Glaucia Mendes Souza, Flavia Stal Papini-Terzi, Flavia Riso Rocha, Alessandro Jaquiel Waclawovsky, Ricardo Zorzetto Nicollielo Vêncio, Josélia Oliveira Marques, Juliana de Maria Felix, Marcelo Menossi Teixeira, Marcos Buckeridge, Amanda Pereira de Souza, Eugênio César Ulian
  • Publication number: 20150183919
    Abstract: Additives are described for use in high solids content epoxy-based corrosion resistant coatings in liquid form, where such additives are composed by microcapsules containing a regenerating agent dispersed in an organic solvent. The coatings, when additivated with such dispersion, will have the ability to self-regenerate in the event of damages (cracks or scratches) to the applied and cured coating on the metal surface, preventing the propagation of corrosion on the exposed metal surface.
    Type: Application
    Filed: August 29, 2012
    Publication date: July 2, 2015
    Applicants: Universidade de São Paulo - USP, PETRÓLEO BRASILEIRO S.A. - PETROBRAS
    Inventors: Marly Grinapel Lachtermacher, Jorge Fernando Pereira Coelho, Andre Koebsch, Pedro Altoe Ferreira, Victor Solymossy, Idalina Vieira Aoki
  • Patent number: 8969041
    Abstract: The present invention refers to: 1) the method for the production of recombinant FVIII in human Sk-Hep-1 cells, comprising von Willebrand Factor (vWF) and 2) the population of human cells transduced with a vector encoding the clotting protein (FVIII). The technical object of the present patent application is intended for the cultivation of human cells in suspension and in adhesion and isolation of the culture medium containing the desired protein. The object of the invention is to provide a safer product (free of potential human viruses), that is cheaper and more stable, by means of a method that provides sufficient amounts and on industrial scale to meet the National demand.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: March 3, 2015
    Assignees: Fundacão Hemocentro de Ribeirão Preto, Universidade de São Paulo
    Inventors: Elisa Maria De Souza Russo Carbolante, Kamilla Swiech, Dimas Tadeu Covas, Virginia Picanco E Castro
  • Patent number: 8747325
    Abstract: The invention application presents a fast, efficient, reproductive alternative of a non-invasive method for diagnosing the severity of heart failure based on a specific biomarker. An additional object of the present invention is a collector device for the biomarker from exhaled breath that is portable, simple, low cost and does not need to run on electric power. This invention advantageously permits the replacement of invasive diagnosis methods, favoring the patient's comfort in addition to the agility and speed of medical attention at hospitals, and may become a standard method for all suspected cases of circulatory disease and heart failure and, more specifically, decompensated heart failure.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: June 10, 2014
    Assignees: Fundacao de Amparo A Pesquisa Do Estado De Sao Paulo (FAPESP), Universidade De Sao Paulo (USP)
    Inventors: Fernando Bacal, Fabiana Goulart Marcondes Braga, Ivano Gebhardt Rolf Gutz, Guilherme Lopes Batista
  • Publication number: 20140057858
    Abstract: The present invention relates to a method for increasing embryo implantation rate in mother's uterus in mammals by administering to the uterus of a mammal an effective amount of beta-galactoside-binding lectin or derivatives thereof, as well as to a product comprising said lectin.
    Type: Application
    Filed: December 9, 2011
    Publication date: February 27, 2014
    Applicants: Inprenha Biotecnologia e Desenvolvimento Avancado Ltda-ME, UNIVERSIDADE DE SAO PAULO - USP
    Inventors: Marcelo Dias Baruffi, Erika da Silva Carvalho Morani, Marcelo Roncoletta, Camillo del Cistia Andrade, Lilian Cataldi Rodrigues