Patents Assigned to Universidade Federal Do Rio Grande Do Sul
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Publication number: 20220153786Abstract: The present invention relates to the use of a peptide to prevent biofilm formation by microorganisms on a surface, wherein said peptide is (i) a peptide consisting of 6 to 37 consecutive amino acids from a peptide of sequence SEQ ID NO: 1, (ii) a peptide of sequence SEQ ID NO: 4, or (iii) a peptidomimetic of (i) or (ii).Type: ApplicationFiled: February 20, 2020Publication date: May 19, 2022Applicants: UNIVERSITE DE RENNES 1, Centre national de la recherche scientifique, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL UFRGSInventors: Rafael GOMES VON BOROWSKI, Aline RIGON ZIMMER, Simone Cristina BAGGIO GNOATTO, Alexandre José MACEDO, Muriel PRIMON DE BARROS, Karine RIGON ZIMMER, Reynald GILLET, Grace GOSMANN
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Patent number: 11046835Abstract: Polymeric compositions may include one or more adjunct polymers selected from a group of an ionomer and a polar polymer; and an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition. Polymer compositions may include a nonpolar matrix polymer; one or more adjuncts selected from the group of an ionomer, a polar polymer, a metal salt, or combinations thereof. Polymer compositions may also include an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition, wherein after at least 17 hours of exposure to the external stimuli, the polymer composition exhibits a ?E of at least 8 or more, maintaining the ?E of at least 8 or more for at least 5 days after the exposure to external stimulus is ceased.Type: GrantFiled: September 12, 2017Date of Patent: June 29, 2021Assignees: Braskem S.A., Universidade Federal do Rio Grande do SulInventors: Márcia Pires Fortes Ferreira, Leonardo Batista Ito, Luciane França De Oliveira, João Henrique Zimnoch dos Santos, Viviane Dalmoro
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Publication number: 20210008224Abstract: The present invention describes a composition for gene therapy of the central nervous system comprising non-viral carriers of nanometric size (<1.0 micrometer) complexed with at least one nucleic acid for purposes of gene therapy via nasal administration, having as main target the central nervous system and the processes for obtaining such carriers. The present invention belongs to the field of nanotechnology and consists of aqueous formulations that can be used in the pharmaceutical and medical fields.Type: ApplicationFiled: July 12, 2018Publication date: January 14, 2021Applicant: Universidade Federal do Rio Grande do SulInventors: Roselena Silvestri Schuh, Helder Ferreira Teixeira, Guilherme Baldo, Ursula Da Silveira Matte, Roberto Giugliani, Juliana Bidone
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Patent number: 10821709Abstract: An article of manufacture includes a first graphene layer, a second graphene layer over the first graphene layer, the second graphene layer oriented at a first interlayer twist angle with respect to the first graphene layer and bonded by interlayer covalent bonds to the first graphene layer, and a third graphene layer over the second graphene layer, the third graphene layer oriented at a second interlayer twist angle with respect to the second graphene layer and bonded by interlayer covalent bonds to the second graphene layer. A multi-layer graphene article includes at least three graphene layers, each graphene layer being oriented at an interlayer twist angle with respect to an adjacent graphene layer and bonded by interlayer covalent bonds to the adjacent graphene layer.Type: GrantFiled: February 13, 2020Date of Patent: November 3, 2020Assignees: University of Massachusetts, Universidade Federal Do Rio Grande Do Sul-UFRGS, The Government of the United States of America, As Represented by the Secretary of the NavyInventors: Christos Dimitrakopoulos, Dimitrios Maroudas, Andre R. Muniz, David Kurt Gaskill
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Patent number: 10822609Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.Type: GrantFiled: December 27, 2013Date of Patent: November 3, 2020Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, Universidade Federal do Rio Grande do SulInventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
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Patent number: 10144817Abstract: The present invention relates to active and intelligent additives having hybrid characteristics, that are compatible with polymers, are thermally and mechanically stable, are capable of releasing electrons and/or photons in the presence of chemical compounds, specifically amino compounds, amide compounds, oxygen reducing compounds, water or vapors thereof. The active and intelligent additives incorporate themselves into polymer matrices allowing the obtainment of active and intelligent polymeric articles. These active and intelligent polymeric articles may act as inhibitors of growth of microorganisms and fungi, as well as indicators of the presence of gasses, either in the atmosphere or caused by the decomposition of foodstuffs, for example.Type: GrantFiled: June 16, 2017Date of Patent: December 4, 2018Assignees: Brasksm S.A., Universidade Federal do Rio Grande do SulInventors: Edwin Moncada, Joao Henrique Zimnoch dos Santos, Larissa Brentano Capeletti
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Patent number: 9994648Abstract: The present invention describes a metallocene catalyst based on a transition metal of group 4 or 5 of the periodic table, supported on a hybrid catalytic support provided with aliphatic organic groups, and a process for supporting metallocene on the hybrid catalytic support. The supported metallocene catalyst provides an ethylene polymer with broad or bimodal molecular weight distribution, in the presence of only one metallocene complex on the support.Type: GrantFiled: June 7, 2017Date of Patent: June 12, 2018Assignees: Braskem S.A., Universidade Federal do Rio Grande do SulInventors: Rodrigo Brambilla, Marcia Silva Lacerda Miranda, Joao Henrique Zimnoch dos Santos, Fernando Silveira
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Patent number: 9988465Abstract: The present invention describes a metallocene catalyst based on a transition metal of group 4 or 5 of the periodic table, supported on a hybrid catalytic support provided with aliphatic organic groups, and a process for supporting metallocene on the hybrid catalytic support. The supported metallocene catalyst provides an ethylene polymer with broad or bimodal molecular weight distribution, in the presence of only one metallocene complex on the support.Type: GrantFiled: June 7, 2017Date of Patent: June 5, 2018Assignees: Braskem S.A., Universidade Federal do Rio Grande do SulInventors: Rodrigo Brambilla, Marcia Silva Lacerda Miranda, Joao Henrique Zimnoch dos Santos, Fernando Silveira
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Publication number: 20180072872Abstract: Polymeric compositions may include one or more adjunct polymers selected from a group of an ionomer and a polar polymer; and an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition. Polymer compositions may include a nonpolar matrix polymer; one or more adjuncts selected from the group of an ionomer, a polar polymer, a metal salt, or combinations thereof. Polymer compositions may also include an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition, wherein after at least 17 hours of exposure to the external stimuli, the polymer composition exhibits a ?E of at least 8 or more, maintaining the ?E of at least 8 or more for at least 5 days after the exposure to external stimulus is ceased.Type: ApplicationFiled: September 12, 2017Publication date: March 15, 2018Applicants: Braskem S.A., Universidade Federal do Rio Grande do SulInventors: Márcia Pires Fortes Ferreira, Leonardo Batista Ito, Luciane França De Oliveira, João Henrique Zimnoch Santos, Viviane Dalmoro
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Patent number: 9868677Abstract: The present invention falls into the context of green chemistry and generically relates to a fertilizing and phytoprotective formulation and, in particular embodiment, to a film forming formulation that induces resistance to plants. The respective formulation, when applied to plants and/or fruits, results in the formation of a film on the surface of the material, which has a characteristic of photoprotection against UV-B and UV-C radiations, resistance kept in water, even after high hygroscopicity, greater stability at high ambient temperatures, formation of desired porosity and surface homogeneity.Type: GrantFiled: December 26, 2013Date of Patent: January 16, 2018Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA—EMBRAPA, Universidade Federal do Rio Grande do SulInventors: Angela Diniz Campos, César Bauer Gomes, Fabiane Grecco Da Silva Porto, Irene Teresinha Santos Garcia, Irajá Ferreira Antunes, Bernardo Ueno, Luis Antônio Suita de Castro, José Francisco Martins Ferreira, Walkyria Bueno Scivittaro
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Patent number: 9700054Abstract: The present invention relates to active and intelligent additives having hybrid characteristics, that are compatible with polymers, are thermally and mechanically stable, are capable of releasing electrons and/or photons in the presence of chemical compounds, specifically amino compounds, amide compounds, oxygen reducing compounds, water or vapors thereof. The active and intelligent additives incorporate themselves into polymer matrices allowing the obtainment of active and intelligent polymeric articles. These active and intelligent polymeric articles may act as inhibitors of growth of microorganisms and fungi, as well as indicators of the presence of gasses, either in the atmosphere or caused by the decomposition of foodstuffs, for example.Type: GrantFiled: September 13, 2011Date of Patent: July 11, 2017Assignees: Braskem S.A., Universidade Federal do Rio Grande do SulInventors: Edwin Moncada, João Henrique Zimnoch don Santos, Larissa Brentano Capeletti
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Patent number: 9580838Abstract: The present invention relates to a process for producing polymeric structures that have activated surfaces. The process proved to be simple, quick, with high production capacity and low operating costs. The process occurs by depositing a polymer solution, which is assisted by a high electric field, on a conductive liquid surface to produce particles and/or filaments that have an activated surface. More particularly, the process of the present invention has the ability to produce particles and/or filaments that have chemically activated surfaces, in a single process.Type: GrantFiled: October 10, 2012Date of Patent: February 28, 2017Assignees: Fundacao Oswaldo Cruz, Universidade Federal do Parana-UFPR, Instituto de Biologia Molecular do Parana-IBMP, Universidade Federal do Rio Grande do Sul-UFRGSInventors: Cyro Ketzer Saul, Elis Moura Stori, Cesar Liberato Petzhold, Wido H. Schreiner, Marco Aurelio Krieger, Leonardo Foti, Andre Sionek, Paula Poli Soares
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Patent number: 9447019Abstract: The present invention relates to fluorine substituted CBD compounds, compositions thereof and uses thereof for the preparation of medicaments.Type: GrantFiled: January 8, 2014Date of Patent: September 20, 2016Assignees: UNIVERSIDADE DE SAO PAULO-USP, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL-UFRGS, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTDInventors: Raphael Mechoulam, Antonio Waldo Zuardi, Flavio Pereira Kapczinski, Jaime Eduardo Cecilio Hallak, Francisco Silveira Guimaraes, Jose Alexandre de Souza Crippa, Aviva Breuer
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Publication number: 20160130430Abstract: Polymeric blends of polystyrene (PS) and polylactic acid (PLA) are described, in the preparation of which a compatibilizing agent was added, preferably a PS-PLA block copolymer. Such compatibilizing agents act controlling phase separation of the blending compounds, and preventing excessive growth of polystyrene domains scattered in the PLA matrix; and this results in blends with good mechanical and thermal resistance.Type: ApplicationFiled: May 16, 2014Publication date: May 12, 2016Applicants: PETROLEO BRASILEIRO S.A. - PETROBRAS, Universidade Federal do Rio Grande do Sul - UFRGSInventors: Vinicius GALHARD GRASSI, Augusto Cesar DE CARVALHO PERES, Marcus Fernando DAL PIZZOL, Joao Manoel DA COSTA, Andreia OSSIG, Cesar LIBERATO PETZHOLD
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Publication number: 20150368649Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.Type: ApplicationFiled: December 27, 2013Publication date: December 24, 2015Applicant: UNIVERSIDADE FEDERAL DO RIO GRANDE DO SULInventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
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Patent number: 9063111Abstract: The present invention relates to chemical sensors with hybrid characteristics, which are thermo-mechanically stable and able to respond to changes in the environment, particularly in the presence of amine and/or amide and/or oxide-reducing compounds, and/or vapor thereof by color change, as well as its incorporation into sensitive polymeric composition.Type: GrantFiled: June 22, 2009Date of Patent: June 23, 2015Assignees: Braskem S.A., Universidade Federal do Rio Grande do SulInventors: Edwin Moncada Acevedo, Gilvan Pozzobon Pires, João Henrique Zimnoch Dos Santos
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Patent number: 8993775Abstract: The present invention refers to the synthesis of precatalysts and the use of such precatalysts in ethylene oligomerization reactions for the selective production of alpha-olefins. More specifically, it refers to the preparation and use of coordination compounds containing polydentate ligands comprising Group 6 and 10 transition metal compounds, in particular chromium (III) and nickel (II). Such catalytic precursors present high catalytic activity and selectivity for the production of alpha-olefins.Type: GrantFiled: September 30, 2011Date of Patent: March 31, 2015Assignees: Petroleo Brasileiro S.A.—Petrobras, Universidade Federal do Rio Grande do Sul-UFRGSInventors: Osvaldo de Lazaro Casagrande Junior, Carlos Rene Klotz Rabello, Lucilene Losch de Oliveira, Ana Helena Dias Pereira dos Santos, Roberta Campedelli, Adao Lauro Bergamo
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Publication number: 20150087866Abstract: The present invention relates to the process of production of olefins by means of the dehydration of light alcohols using ionic liquids as an acidic medium. Furthermore, the present invention relates to the use of such olefins, for example, for the production of polymers and ethylene glycol.Type: ApplicationFiled: August 30, 2012Publication date: March 26, 2015Applicants: UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL-UFRGS, BRASKEM S.A.Inventor: Michèle Oberson De Souza
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Publication number: 20140246812Abstract: The present invention relates to a process for producing polymeric structures that have activated surfaces. The process proved to be simple, quick, with high production capacity and low operating costs. The process occurs by depositing a polymer solution, which is assisted by a high electric field, on a conductive liquid surface to produce particles and/or filaments that have an activated surface. More particularly, the process of the present invention has the ability to produce particles and/or filaments that have chemically activated surfaces, in a single process.Type: ApplicationFiled: October 10, 2012Publication date: September 4, 2014Applicants: Fundacao Oswaldo Cruz, Universidade Federal do Parana-UFPR, Instituto de Biologia Molecular do Parana-IBMP, Universidade Federal do Rio Grande do Sul-UFRGSInventors: Cyro Ketzer Saul, Elis Moura Stori, Cesar Liberato Petzhold, Wido H. Schreiner, Marco Aurelio Krieger, Leonardo Foti, Andre Sionek, Paula Poli Soares
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Patent number: 8568788Abstract: The present invention relates to a nanoparticulated anaesthetic composition for topical use in which at least one local anaesthetic agent is encapsulated in polymeric nanoparticles. The present invention also relates to the use of such polymeric nanoparticles comprising at least one local anaesthetic agent in the preparation of an anaesthetic composition for topical application to the skin or mucosa.Type: GrantFiled: March 12, 2008Date of Patent: October 29, 2013Assignees: Biolab Sanus Farmaceutica Ltda, Universidade Federal Do Rio Grande Do SulInventors: Dante Alário Junior, Silvia Stanisçuski Guterres, Adriana Raffin Pohlmann, Lali Rosoni Zancan