Patents Assigned to Universidade Federal Do Rio Grande Do Sul
  • Publication number: 20220153786
    Abstract: The present invention relates to the use of a peptide to prevent biofilm formation by microorganisms on a surface, wherein said peptide is (i) a peptide consisting of 6 to 37 consecutive amino acids from a peptide of sequence SEQ ID NO: 1, (ii) a peptide of sequence SEQ ID NO: 4, or (iii) a peptidomimetic of (i) or (ii).
    Type: Application
    Filed: February 20, 2020
    Publication date: May 19, 2022
    Applicants: UNIVERSITE DE RENNES 1, Centre national de la recherche scientifique, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL UFRGS
    Inventors: Rafael GOMES VON BOROWSKI, Aline RIGON ZIMMER, Simone Cristina BAGGIO GNOATTO, Alexandre José MACEDO, Muriel PRIMON DE BARROS, Karine RIGON ZIMMER, Reynald GILLET, Grace GOSMANN
  • Patent number: 11046835
    Abstract: Polymeric compositions may include one or more adjunct polymers selected from a group of an ionomer and a polar polymer; and an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition. Polymer compositions may include a nonpolar matrix polymer; one or more adjuncts selected from the group of an ionomer, a polar polymer, a metal salt, or combinations thereof. Polymer compositions may also include an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition, wherein after at least 17 hours of exposure to the external stimuli, the polymer composition exhibits a ?E of at least 8 or more, maintaining the ?E of at least 8 or more for at least 5 days after the exposure to external stimulus is ceased.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: June 29, 2021
    Assignees: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Márcia Pires Fortes Ferreira, Leonardo Batista Ito, Luciane França De Oliveira, João Henrique Zimnoch dos Santos, Viviane Dalmoro
  • Publication number: 20210008224
    Abstract: The present invention describes a composition for gene therapy of the central nervous system comprising non-viral carriers of nanometric size (<1.0 micrometer) complexed with at least one nucleic acid for purposes of gene therapy via nasal administration, having as main target the central nervous system and the processes for obtaining such carriers. The present invention belongs to the field of nanotechnology and consists of aqueous formulations that can be used in the pharmaceutical and medical fields.
    Type: Application
    Filed: July 12, 2018
    Publication date: January 14, 2021
    Applicant: Universidade Federal do Rio Grande do Sul
    Inventors: Roselena Silvestri Schuh, Helder Ferreira Teixeira, Guilherme Baldo, Ursula Da Silveira Matte, Roberto Giugliani, Juliana Bidone
  • Patent number: 10821709
    Abstract: An article of manufacture includes a first graphene layer, a second graphene layer over the first graphene layer, the second graphene layer oriented at a first interlayer twist angle with respect to the first graphene layer and bonded by interlayer covalent bonds to the first graphene layer, and a third graphene layer over the second graphene layer, the third graphene layer oriented at a second interlayer twist angle with respect to the second graphene layer and bonded by interlayer covalent bonds to the second graphene layer. A multi-layer graphene article includes at least three graphene layers, each graphene layer being oriented at an interlayer twist angle with respect to an adjacent graphene layer and bonded by interlayer covalent bonds to the adjacent graphene layer.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: November 3, 2020
    Assignees: University of Massachusetts, Universidade Federal Do Rio Grande Do Sul-UFRGS, The Government of the United States of America, As Represented by the Secretary of the Navy
    Inventors: Christos Dimitrakopoulos, Dimitrios Maroudas, Andre R. Muniz, David Kurt Gaskill
  • Patent number: 10822609
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: November 3, 2020
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, Universidade Federal do Rio Grande do Sul
    Inventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
  • Patent number: 10144817
    Abstract: The present invention relates to active and intelligent additives having hybrid characteristics, that are compatible with polymers, are thermally and mechanically stable, are capable of releasing electrons and/or photons in the presence of chemical compounds, specifically amino compounds, amide compounds, oxygen reducing compounds, water or vapors thereof. The active and intelligent additives incorporate themselves into polymer matrices allowing the obtainment of active and intelligent polymeric articles. These active and intelligent polymeric articles may act as inhibitors of growth of microorganisms and fungi, as well as indicators of the presence of gasses, either in the atmosphere or caused by the decomposition of foodstuffs, for example.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: December 4, 2018
    Assignees: Brasksm S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Edwin Moncada, Joao Henrique Zimnoch dos Santos, Larissa Brentano Capeletti
  • Patent number: 9994648
    Abstract: The present invention describes a metallocene catalyst based on a transition metal of group 4 or 5 of the periodic table, supported on a hybrid catalytic support provided with aliphatic organic groups, and a process for supporting metallocene on the hybrid catalytic support. The supported metallocene catalyst provides an ethylene polymer with broad or bimodal molecular weight distribution, in the presence of only one metallocene complex on the support.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: June 12, 2018
    Assignees: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Rodrigo Brambilla, Marcia Silva Lacerda Miranda, Joao Henrique Zimnoch dos Santos, Fernando Silveira
  • Patent number: 9988465
    Abstract: The present invention describes a metallocene catalyst based on a transition metal of group 4 or 5 of the periodic table, supported on a hybrid catalytic support provided with aliphatic organic groups, and a process for supporting metallocene on the hybrid catalytic support. The supported metallocene catalyst provides an ethylene polymer with broad or bimodal molecular weight distribution, in the presence of only one metallocene complex on the support.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: June 5, 2018
    Assignees: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Rodrigo Brambilla, Marcia Silva Lacerda Miranda, Joao Henrique Zimnoch dos Santos, Fernando Silveira
  • Publication number: 20180072872
    Abstract: Polymeric compositions may include one or more adjunct polymers selected from a group of an ionomer and a polar polymer; and an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition. Polymer compositions may include a nonpolar matrix polymer; one or more adjuncts selected from the group of an ionomer, a polar polymer, a metal salt, or combinations thereof. Polymer compositions may also include an intelligent additive, wherein when exposed to the external stimuli, the intelligent additive triggers a color change in the polymeric composition, wherein after at least 17 hours of exposure to the external stimuli, the polymer composition exhibits a ?E of at least 8 or more, maintaining the ?E of at least 8 or more for at least 5 days after the exposure to external stimulus is ceased.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 15, 2018
    Applicants: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Márcia Pires Fortes Ferreira, Leonardo Batista Ito, Luciane França De Oliveira, João Henrique Zimnoch Santos, Viviane Dalmoro
  • Patent number: 9868677
    Abstract: The present invention falls into the context of green chemistry and generically relates to a fertilizing and phytoprotective formulation and, in particular embodiment, to a film forming formulation that induces resistance to plants. The respective formulation, when applied to plants and/or fruits, results in the formation of a film on the surface of the material, which has a characteristic of photoprotection against UV-B and UV-C radiations, resistance kept in water, even after high hygroscopicity, greater stability at high ambient temperatures, formation of desired porosity and surface homogeneity.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: January 16, 2018
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA—EMBRAPA, Universidade Federal do Rio Grande do Sul
    Inventors: Angela Diniz Campos, César Bauer Gomes, Fabiane Grecco Da Silva Porto, Irene Teresinha Santos Garcia, Irajá Ferreira Antunes, Bernardo Ueno, Luis Antônio Suita de Castro, José Francisco Martins Ferreira, Walkyria Bueno Scivittaro
  • Patent number: 9700054
    Abstract: The present invention relates to active and intelligent additives having hybrid characteristics, that are compatible with polymers, are thermally and mechanically stable, are capable of releasing electrons and/or photons in the presence of chemical compounds, specifically amino compounds, amide compounds, oxygen reducing compounds, water or vapors thereof. The active and intelligent additives incorporate themselves into polymer matrices allowing the obtainment of active and intelligent polymeric articles. These active and intelligent polymeric articles may act as inhibitors of growth of microorganisms and fungi, as well as indicators of the presence of gasses, either in the atmosphere or caused by the decomposition of foodstuffs, for example.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: July 11, 2017
    Assignees: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Edwin Moncada, João Henrique Zimnoch don Santos, Larissa Brentano Capeletti
  • Patent number: 9580838
    Abstract: The present invention relates to a process for producing polymeric structures that have activated surfaces. The process proved to be simple, quick, with high production capacity and low operating costs. The process occurs by depositing a polymer solution, which is assisted by a high electric field, on a conductive liquid surface to produce particles and/or filaments that have an activated surface. More particularly, the process of the present invention has the ability to produce particles and/or filaments that have chemically activated surfaces, in a single process.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: February 28, 2017
    Assignees: Fundacao Oswaldo Cruz, Universidade Federal do Parana-UFPR, Instituto de Biologia Molecular do Parana-IBMP, Universidade Federal do Rio Grande do Sul-UFRGS
    Inventors: Cyro Ketzer Saul, Elis Moura Stori, Cesar Liberato Petzhold, Wido H. Schreiner, Marco Aurelio Krieger, Leonardo Foti, Andre Sionek, Paula Poli Soares
  • Patent number: 9447019
    Abstract: The present invention relates to fluorine substituted CBD compounds, compositions thereof and uses thereof for the preparation of medicaments.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: September 20, 2016
    Assignees: UNIVERSIDADE DE SAO PAULO-USP, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL-UFRGS, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventors: Raphael Mechoulam, Antonio Waldo Zuardi, Flavio Pereira Kapczinski, Jaime Eduardo Cecilio Hallak, Francisco Silveira Guimaraes, Jose Alexandre de Souza Crippa, Aviva Breuer
  • Publication number: 20160130430
    Abstract: Polymeric blends of polystyrene (PS) and polylactic acid (PLA) are described, in the preparation of which a compatibilizing agent was added, preferably a PS-PLA block copolymer. Such compatibilizing agents act controlling phase separation of the blending compounds, and preventing excessive growth of polystyrene domains scattered in the PLA matrix; and this results in blends with good mechanical and thermal resistance.
    Type: Application
    Filed: May 16, 2014
    Publication date: May 12, 2016
    Applicants: PETROLEO BRASILEIRO S.A. - PETROBRAS, Universidade Federal do Rio Grande do Sul - UFRGS
    Inventors: Vinicius GALHARD GRASSI, Augusto Cesar DE CARVALHO PERES, Marcus Fernando DAL PIZZOL, Joao Manoel DA COSTA, Andreia OSSIG, Cesar LIBERATO PETZHOLD
  • Publication number: 20150368649
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Application
    Filed: December 27, 2013
    Publication date: December 24, 2015
    Applicant: UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL
    Inventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
  • Patent number: 9063111
    Abstract: The present invention relates to chemical sensors with hybrid characteristics, which are thermo-mechanically stable and able to respond to changes in the environment, particularly in the presence of amine and/or amide and/or oxide-reducing compounds, and/or vapor thereof by color change, as well as its incorporation into sensitive polymeric composition.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: June 23, 2015
    Assignees: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Edwin Moncada Acevedo, Gilvan Pozzobon Pires, João Henrique Zimnoch Dos Santos
  • Patent number: 8993775
    Abstract: The present invention refers to the synthesis of precatalysts and the use of such precatalysts in ethylene oligomerization reactions for the selective production of alpha-olefins. More specifically, it refers to the preparation and use of coordination compounds containing polydentate ligands comprising Group 6 and 10 transition metal compounds, in particular chromium (III) and nickel (II). Such catalytic precursors present high catalytic activity and selectivity for the production of alpha-olefins.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: March 31, 2015
    Assignees: Petroleo Brasileiro S.A.—Petrobras, Universidade Federal do Rio Grande do Sul-UFRGS
    Inventors: Osvaldo de Lazaro Casagrande Junior, Carlos Rene Klotz Rabello, Lucilene Losch de Oliveira, Ana Helena Dias Pereira dos Santos, Roberta Campedelli, Adao Lauro Bergamo
  • Publication number: 20150087866
    Abstract: The present invention relates to the process of production of olefins by means of the dehydration of light alcohols using ionic liquids as an acidic medium. Furthermore, the present invention relates to the use of such olefins, for example, for the production of polymers and ethylene glycol.
    Type: Application
    Filed: August 30, 2012
    Publication date: March 26, 2015
    Applicants: UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL-UFRGS, BRASKEM S.A.
    Inventor: Michèle Oberson De Souza
  • Publication number: 20140246812
    Abstract: The present invention relates to a process for producing polymeric structures that have activated surfaces. The process proved to be simple, quick, with high production capacity and low operating costs. The process occurs by depositing a polymer solution, which is assisted by a high electric field, on a conductive liquid surface to produce particles and/or filaments that have an activated surface. More particularly, the process of the present invention has the ability to produce particles and/or filaments that have chemically activated surfaces, in a single process.
    Type: Application
    Filed: October 10, 2012
    Publication date: September 4, 2014
    Applicants: Fundacao Oswaldo Cruz, Universidade Federal do Parana-UFPR, Instituto de Biologia Molecular do Parana-IBMP, Universidade Federal do Rio Grande do Sul-UFRGS
    Inventors: Cyro Ketzer Saul, Elis Moura Stori, Cesar Liberato Petzhold, Wido H. Schreiner, Marco Aurelio Krieger, Leonardo Foti, Andre Sionek, Paula Poli Soares
  • Patent number: 8568788
    Abstract: The present invention relates to a nanoparticulated anaesthetic composition for topical use in which at least one local anaesthetic agent is encapsulated in polymeric nanoparticles. The present invention also relates to the use of such polymeric nanoparticles comprising at least one local anaesthetic agent in the preparation of an anaesthetic composition for topical application to the skin or mucosa.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: October 29, 2013
    Assignees: Biolab Sanus Farmaceutica Ltda, Universidade Federal Do Rio Grande Do Sul
    Inventors: Dante Alário Junior, Silvia Stanisçuski Guterres, Adriana Raffin Pohlmann, Lali Rosoni Zancan