Abstract: The present invention relates to methods for determining the concentration of a free beta-lactam antibiotic in a biological sample. In particular, the present invention relates to methods for measuring a free beta-lactam antibiotic in a biological sample, comprising the steps of: (a) providing at least one class C beta-lactamase, a functional fragment or variant thereof; (b) providing at least one biological sample; (c) contacting said at least one class C beta-lactamase with said at least one biological sample; and (d) determining the concentration of said free beta-lactam antibiotic in said at least one biological sample.
Type:
Grant
Filed:
October 15, 2012
Date of Patent:
June 27, 2017
Assignees:
UNIVERSITÉ DE LIÈGE, UNIVERSITÉ CATHOLIQUE DE LOUVAIN, UNIVERSITÉ LIBRE DE BRUXELLES, UNIVERSITÉ DE MONS-HAINAUT
Inventors:
Alain Brans, Bernard Joris, Michael Delmarcelle, Jacqueline Marchand, Paul Tulkens, Catherine Hammaecher, Erik Goormaghtigh, Joel De Coninck
Abstract: Antigens of Mycobacterium avium subsp. paratuberculosis, antigenic compositions include at least two of the antigens, as well as epitopes, antibodies or hypervariable fragments thereof and nucleotide sequences coding for them. The antigens are used in diagnosis and/or vaccination against Mycobacterium avium subsp. paratuberculosis, in mammals, and in particular in cattle, but also in sheep and caprines. The antigens have potential application in diagnosis and/or vaccination against Crohn's disease in humans.
Type:
Application
Filed:
November 6, 2007
Publication date:
August 18, 2011
Applicants:
Universite de Mons Hainaut, Cerva-Coda, Institut Scientifique de Sante Publique
Abstract: A grafted polymer and its use in polymer/liquid crystal composite films, and more particularly in PDLC films, is disclosed. The grafted polymer includes (alkyl)acrylic acid or (alkyl)acrylamide moieties. At least one of the moieties is grafted with an alkylphenol or with an alkoxylated alkylphenol.
Type:
Application
Filed:
May 5, 2006
Publication date:
March 11, 2010
Applicants:
Universite De Mons Hainaut, Universite Du Litteral Cote Opale, Materia Nova ASBL
Inventors:
Benoit Duponchel, Abdelaziz Elass, Mourad Boussoualem, Jean-Marc Buisine, Joel De Coninck, Valerie Celine Ledauphin, Mickael Coquelet, Alexandre Vaillant
Abstract: The present invention is related to an isolated and purified peroxisome-associated polypeptide. The present invention is also related to the nucleotide sequence encoding said amino sequence, the inhibitor directed against said sequences and their use in the diagnosis, treatment, and/or prevention of lung injuries or diseases and oxidative stress-related disorders.
Type:
Grant
Filed:
August 15, 2000
Date of Patent:
July 6, 2004
Assignees:
Universite Catholique de Louvain, Universite de Mons-Hainaut
Inventors:
Bernard Knoops, Cedric Hermans, Alfred Bernard, Ruddy Wattiez, Paul Falmagne