Patents Assigned to Université Joseph Fourier
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Patent number: 9568482Abstract: Provided are antibodies specific for ZnT8. In particular, provided are monoclonal or polyclonal non-naturally occurring antibodies which specifically recognizes an epitope selected from the group consisting of SEQ ID NO. 7, SEQ ID NO. 8, SEQ ID NO. 9 and SEQ ID NO. 10 as described herein.Type: GrantFiled: October 19, 2010Date of Patent: February 14, 2017Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE, UNIVERSITE JOSEPH FOURIERInventors: Michel Seve, Alain Favier
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Patent number: 9570317Abstract: A microelectronic method for etching a layer to be etched, including: modifying the layer to be etched from a surface of the layer to be etched and over a depth corresponding to at least a portion of thickness of the layer to be etched to form a film, with the modifying including implanting light ions into the layer to be etched; and removing the film includes a selective etching of the film relative to at least one layer underlying the film.Type: GrantFiled: December 20, 2013Date of Patent: February 14, 2017Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JOSEPH FOURIERInventors: Nicolas Posseme, Olivier Joubert, Laurent Vallier
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Publication number: 20170023497Abstract: The invention concerns a device for measuring parasitic movements in a sample (5) to be analysed in an X-ray tomography apparatus, the device comprising: a source (1) emitting an X-ray beam (6) to a detector (3), the sample, carried by a support (13), being traversed by the beam; and a sight (17) carrying at least three balls (21) that are opaque to X-rays, the sight being attached to said support such that, on the detector, images (25) of the balls are around an image (16) of the sample, the shape and the materials of the sight being chosen such that the positions of the balls relative to the support are insensitive to temperature variations.Type: ApplicationFiled: April 7, 2015Publication date: January 26, 2017Applicant: Universite Joseph FourierInventors: Simon SALAGER, Edward Carlo Giorgio ANDO, Jacques DESRUES
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Patent number: 9505055Abstract: A method for removing a part from a mold and to a machine for molding the part, the part made of a material having a glass-transition temperature and a melting temperature that is higher than the glass-transition temperature, and which is shaped in the cavity of a mold, includes at least two mold portions defining the shaping cavity therebetween. The mold is at a temperature between the glass-transition temperature and the melting temperature. The method includes opening the mold by spacing apart the mold portions, locally spraying a cooling gas toward the part remaining in a portion of the mold using at least one nozzle, and, after a predetermined time period following the start of spraying the gas, ejecting the part from the portion of the mold, the time period being such that the part reaches a temperature that is lower than the glass-transition temperature thereof.Type: GrantFiled: June 1, 2012Date of Patent: November 29, 2016Assignees: UNIVERSITE JOSEPH FOURIER, INSTITUT POLYTECHNIQUE DE GRENOBLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Sébastien Gravier, Georges Kapelski, Jean-Jacques Blandin, Charles Josserond
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Patent number: 9508920Abstract: A voltage-controlled spintronic device includes a magnetic layer having an effective anisotropy Keff; a non-magnetic insulating layer; a contact layer; the magnetic layer having an anisotropy switching threshold such that application of a polarization voltage Vmax allows switching of the effective anisotropy Keff from a direction perpendicular to the reference plane to a direction in the reference plane or vice versa, the magnetic layer including a first layer, with thickness tB, having a volume anisotropy KVB; a second layer, with thickness tA, having a surface anisotropy KSA and a volume anisotropy KVA; the surface anisotropy KSA and the volume anisotropies KVA and KVB respecting, over a given operating temperature range: Min(KSA(V=0), KSA(V=Vmax))<?{KVBtB+KVAtA)<Max(KSA(V=0), KSA(V=Vmax)). KSA(V=0) is the surface anisotropy when no polarization voltage is applied. KSA(V=Vmax) is the surface anisotropy when a polarization voltage Vmax is applied.Type: GrantFiled: July 18, 2014Date of Patent: November 29, 2016Assignees: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ JOSEPH FOURIERInventors: Bernard Dieny, Hélène Bea, Sébastien Bandiera
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Patent number: 9493761Abstract: The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.Type: GrantFiled: February 29, 2012Date of Patent: November 15, 2016Assignees: UNIVERSITE JOSEPH FOURIER (GRENOBLE 1), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Benoit Polack, Aline Thomas
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Patent number: 9453837Abstract: Novel grafted dinuclear metal complexes having formula (I) or of formula (II) wherein M represents a metal ion, and also the use thereof as sensors in a method for detecting and/or characterising cellular microparticles.Type: GrantFiled: March 23, 2012Date of Patent: September 27, 2016Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE CAEN BASSE-NORMANDIE, UNIVERSITE JOSEPH FOURIERInventors: Catherine Belle, Gisele Gellon, Laurent Plawinski, Loic Doeuvre, Eduardo Angles Cano
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Patent number: 9455012Abstract: A magnetic device includes a first magnetic layer, known as storage layer, having a uniaxial anisotropy with an easy magnetization axis in the plane of the storage layer and having a magnetization of variable direction having two positions of equilibrium along the easy magnetization axis, a second magnetic layer, known as electron spin polarization layer, having a magnetization perpendicular to that of the storage layer and situated out of plane of the electron spin polarization layer, a device configured to make circulate in the layers, and perpendicularly thereto, a current to switch from one position of equilibrium of the direction of magnetization of the storage layer to the other. The device further includes a device to apply a magnetic field, known as transverse field, the direction of which is substantially parallel to the plane of the storage layer and substantially perpendicular to the easy magnetization axis of the storage layer.Type: GrantFiled: November 25, 2015Date of Patent: September 27, 2016Assignees: COMMISSARIAT A L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIC (CNRS), UNIVERSITE JOSEPH FOURIER GRENOBLE, UNIVERSITÉPARIS SUDInventors: Bernard Dieny, Ricardo Sousa, Bertrand Lacoste, Thibaut Devolder
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Patent number: 9439975Abstract: The invention relates to small cell penetrating peptides (CPP) derived from the scorpion toxin maurocalcine and to their use as vectors for the intracellular delivery of various drugs and agents.Type: GrantFiled: June 20, 2012Date of Patent: September 13, 2016Assignees: Commissariat A L'Energie Atomique Et Aux Energies Alternatives, Institut National De La Sante Et De La Recherche Medicale (Inserm), Universite Joseph FourierInventor: Michel De Waard
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Patent number: 9382639Abstract: A device for crystallizing a molecule to be crystallized, which includes: at least one crystallization cell that includes a crystallization chamber for receiving a first solution S1 containing the molecule to be crystallized and the crystal seeds thereof, a dialysis membrane, and a container to be filled with a second solution S2 that contains constituents selected from the group containing crystallization agents, additives and buffers; and at least one image acquisition means. The crystallization device is characterized in that it includes: at least one addition means arranged to add, to the container, constituents selected from the group containing crystallization agents, additives and buffers of solution S2; and/or at least one sampling means arranged to collect, from the container, all or a portion of solution S2. The invention also relates to a crystallization method.Type: GrantFiled: September 15, 2011Date of Patent: July 5, 2016Assignee: UNIVERSITE JOSEPH FOURIERInventor: Monika Spano
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Publication number: 20160158800Abstract: A process of manufacturing component with a composite film including a matrix made of thermoplastic polymer and particles inside this matrix. This process includes heating the composite film in order for its temperature to exceed the glass transition temperature of its matrix, then when the composite film is softened, flattening an external face of the composite film by a smooth face resting directly over the whole of this external face, this smooth face forming part of the front face of a flexible membrane, the whole of the rear face of which, located on the side opposite the front face, is pushed against the composite film by a fluid, then cooling the composite film below the glass transition temperature, then withdrawing the membrane in order to mechanically separate its front face from the external face of the composite film.Type: ApplicationFiled: December 3, 2015Publication date: June 9, 2016Applicants: Commissariat a L'Energie Atomique et aux Energies Alternatives, Centre National de la Recherche Scientifique, Universite Joseph FourierInventors: Bernard VIALA, Helene TAKACS, Jean-Herve TORTAl
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Publication number: 20160159937Abstract: The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions.Type: ApplicationFiled: February 12, 2016Publication date: June 9, 2016Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1Inventors: Rachel AUZELY, Jimmy MERGY, Eric BAYMA-PECIT
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Publication number: 20160151179Abstract: A spacer including a first part made from a first shape memory material, and a second part made from a second shape memory material.Type: ApplicationFiled: June 20, 2014Publication date: June 2, 2016Applicants: Universite Joseph Fourier, Centre National de la Recherche Scientifique, Assistance Publique - Hopitaux De ParisInventors: Denis FAVIER, Pierre MOZER, Yohan PAYAN, Gabriel Antherieu, Nathanael CONNESSON
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Patent number: 9337034Abstract: The invention relates to a method for producing a component comprising a conductive grid insulated from a semiconductor monocrystalline diamond substrate by an insulating region, comprising the following steps: a) oxygenating the surface of the substrate so as to replace the hydrogen surface terminations of the substrate with oxygen surface terminations; and b) forming the insulating region on the surface of the substrate by repeated monatomic layer deposition.Type: GrantFiled: December 20, 2012Date of Patent: May 10, 2016Assignees: Centre National de la Recherche Scientifique, Universite Joseph FourierInventors: Gauthier Chicot, Aurélien Marechal, Pierre Muret, Julien Pernot
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Publication number: 20160116613Abstract: The invention relates to a matrix device for measuring characteristics of an X-ray beam. The device includes a first set of detection cells of a size different from the cells of at least one second set of detection cells. Each cell corresponds to an ionization chamber including a detection electrode. The detection electrodes of all the cells have the same effective surface for collecting charges.Type: ApplicationFiled: May 15, 2014Publication date: April 28, 2016Applicants: Centre National de la Recherche Scientifique, Universite Joseph FourierInventors: Yannick Arnoud, Olivier Guillaudin
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Patent number: 9321722Abstract: The present invention relates to novel bis-indolic derivatives, processes for their preparation, and their potential use as new antibacterial drugs.Type: GrantFiled: July 20, 2012Date of Patent: April 26, 2016Assignee: UNIVERSITE JOSEPH FOURIERInventors: Jean-Noël Denis, Claude Marcelle Jolivalt, Louis Maurin Max Maurin, Olga Nikolaevna Burchak
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Publication number: 20160071936Abstract: A method for producing a Schottky diode, including the following steps: oxygenating the surface of a semiconductive layer of monocrystalline diamond, in such a way as to replace hydrogen surface terminations of the semiconductive layer with oxygen surface terminations; and forming, by physical vapour deposition, a first conductive layer of zirconium or indium-tin oxide on the surface of the semiconductive layer.Type: ApplicationFiled: April 18, 2014Publication date: March 10, 2016Applicants: Centre National de la Recherche Scientifique, Universite Joseph Fourier, Institut Polytechnique de GrenobleInventors: David Eon, Etienne Gheeraert, Pierre Muret, Julien Pernot, Aboulaye Traore
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Publication number: 20160035581Abstract: A microelectronic method for etching a layer to be etched, including: modifying the layer to be etched from a surface of the layer to be etched and over a depth corresponding to at least a portion of thickness of the layer to be etched to form a film, with the modifying including implanting light ions into the layer to be etched; and removing the film includes a selective etching of the film relative to at least one layer underlying the film.Type: ApplicationFiled: December 20, 2013Publication date: February 4, 2016Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JOSEPH FOURIERInventors: Nicolas POSSEME, Olivier JOUBERT, Laurent VALLIER
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Patent number: 9244029Abstract: The use of a vapor source (10) in an isothermal system (8) to control the crystallization or recrystallization of a sample of solid material (9) which is initially at least partially amorphous and/or at least partially crystalline and contained within the system (8), the vapor source (10) including at least one solvent for crystallizing the solid material, the vapor diffusion (14) of which leads to the crystallization or recrystallization of the sample (9), the vapor source (10) being such that the quantities of heat exchanged within the system during the crystallization or recrystallization of the sample (9) other than the heat of crystallization or recrystallization of the sample are less than approximately 10%, particularly 5%, and advantageously 1% of the heat of crystallization or recrystallization of the sample. The vapor source (10) is preferably a pure solvent or a solvent mixture in which no solute is dissolved.Type: GrantFiled: December 10, 2009Date of Patent: January 26, 2016Assignee: UNIVERSITE JOSEPH FOURIERInventors: Nawale Khalef, Aziz Bakri
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Publication number: 20160007952Abstract: An image processing method enables an elasticity image of a body including a cavity to be produced on the basis of the material(s) forming the body, wherein the method includes the steps of: receiving a deformation image illustrating a field of movement of the points of the body on the basis of a pressure difference in the body, estimating a shape function of the body from the deformation image, calculating an elasticity image of the body on the basis of the shape function, of the pressure difference and of the deformation image.Type: ApplicationFiled: February 17, 2014Publication date: January 14, 2016Applicant: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1Inventors: Jacques OHAYON, Flavien DELEAVAL, Guy CLOUTIER