Abstract: The present invention relates to a quantum computing unit comprising a superconducting substrate or other superconducting component, at least three outer Majorana modes, and at least one inner Majorana mode, wherein the at least three outer Majorana modes are located along an outer perimeter, and wherein the at least one inner Majorana mode is located within the outer perimeter. This spatial configuration of the four participating Majorana modes allows to control the time-dependent coupling between the respective Majorana modes. The related quantum gates can be performed perfectly in a finite time, preferably with a frequency of up to several GHz. These include the braiding gate, the ?/8 magic phase gate, the ?/12 phase gate, and, for multi-qubit systems, the CNOT gate. The robustness of the mechanism guarantees that for special times the quantum gate is conducted the quantum gate is perfectly realized. This property is independent of material specific parameters.

Abstract: Method for applying a nanolaminate to a metal workpiece, wherein a coating made of a nanolaminate is applied in a region that is subjected to a notch effect, for example, a weld seam, which nanolaminate consists of a series of at least two metal layers, wherein each metal layer consists of a metal or a metal alloy that differs from the metal or the metal alloy in the adjacent layer. According to the invention, the method can take place with a batching tank locally and/or in situ.

Abstract: A system and methods for determining a mechanical tissue characteristic (?) are provided. The system comprises a providing unit for providing a set of images of a tissue region of interest, wherein the provided set of images comprises image features indicative of one or more structural properties (?, a0, CO, PG) of the tissue region of interest and has been acquired using an imaging modality suitable for in-vivo imaging of the tissue region of interest. The system further comprises a determining unit for determining, based on the provided set of images, a mechanical tissue characteristic (?) indicative of a mechanical responsiveness of the tissue region of interest. The determining unit comprises a machine learning architecture adapted to receive the provided set of images as an input and to provide the mechanical tissue characteristic as an output.

Abstract: Medical training model having at least one blood vessel model (1) which in at least one practice region can be connected to an anatomically replicated substitute blood circulation system (2) and in which a real instrument (17) is used, further having an image recording device (3) for creating measured images of the at least one blood vessel model (1), and having an image processing device (11) which converts the recorded measured images into an imaging blood vessel representation and makes same displayable on a screen (12), wherein the image recording device (3) is designed as a photo-optical system (8) which records transmitted-light images (13) as measured images of the at least one blood vessel model (1) for simulation of medical activity, for which purpose the at least one blood vessel model (1) is replicated in a transparently produced solid-bdy block (4) for a contrast between transparent solid-body block (4) and non-transparent instrument (17).

Abstract: A computer-implemented method to capture and detect clusters in, or determined by, a set V of discrete digital data comprising; computing, from the set V, an abstract separation system ASS that consists of a finite set S, whose elements are called separations; of a predetermined transitive, antisymmetric and reflexive order relation ? on S; and of an order-reversing involution *: S?S, that is, a mapping s?s* with the property that, (s*)*=s and that r?s implies s*<r* for all r, s?S; predetermining a set of consistency requirements (CRs), that is, a set F of subsets of S; computing, from the ASS (S,?, *), one or more abstract tangles, that is, any set T?S that contains exactly one of each pair {s, s*} for s?S, and does not contain any of the forbidden configurations F?F as a subset; or determining that there is no abstract tangle; and determining that any abstract tangle T represents a cluster in, or determined by, the data set V.

Abstract: A method for coating one or more channels of a sample using a vapor deposition includes alternatingly supplying at least two gaseous precursor to one or more channels defined in a sample through at least one feed line that is connected to a first channel end of the one or more channels. An adjustable pressure gradient is generated and conducts the at least two gaseous precursors along a first flow direction (SR1) from the at least one feed line to a first discharge line through the one or more channels. The at least two gaseous precursor and reaction products are discharged from the one or more channels through a first discharge line that is connected to a second channel end of the one or more channels of the sample. Non-reacted precursors and reaction products are discharged through a second discharge line that is connected to the first channel end.

Abstract: A device for generating laser radiation comprises a temperature-controlled optical setup comprising an optically non-linear solid state medium arranged in a resonator and an active region. The outgoing laser radiation is generated from a pump beam introduced into the optically non-linear solid state medium. A first temperature actuator and a second temperature actuator configured to independently adjust temperature values in the active region of the optically non-linear solid state medium. The first temperature actuator is configured regulate a length of the resonator by setting a first temperature value within a first portion of the active region. The second temperature actuator is configured to match phases of wavelengths generated by the outgoing laser radiation and phases of wavelengths of the pump beam radiation by setting a second temperature value within a second portion of the active region.

Abstract: A device for generating laser radiation comprises a temperature-controlled optical setup comprising an optically non-linear solid state medium arranged in a resonator and an active region. The outgoing laser radiation is generated from a pump beam introduced into the optically non-linear solid state medium. A first temperature actuator and a second temperature actuator configured to independently adjust temperature values in the active region of the optically non-linear solid state medium. The first temperature actuator is configured regulate a length of the resonator by setting a first temperature value within a first portion of the active region. The second temperature actuator is configured to match phases of wavelengths generated by the outgoing laser radiation and phases of wavelengths of the pump beam radiation by setting a second temperature value within a second portion of the active region.

Abstract: A method to determine the throughput speed v of a pore, comprising the steps of feeding, by means of a driving force F, a filiform calibration element through the pore, the calibration element having a plurality of markers spaced apart by known distances and configured to produce an interaction event that transmits a signal away from the pore upon interaction with the pore, detecting a plurality of interaction events, and determining a time interval ?t between successive interaction events, and/or a frequency ? of interaction events.

Abstract: The invention proposes an In-situ Sensor (1) for being implanted within tissue of a mammal (P) comprising •an energy harvesting portion (RX), •a communication portion (TX), •a pressure sensor (SP) for measuring interstitial pressure of surrounding tissue when located within tissue, •a further sensor (SF), whereby the further sensor is selected from a group comprising pH sensor, lactate sensor, impedance sensor, radiation sensor, temperature sensor, sensor for bioelectrical potentials, •whereby said further sensor (SF), said pressure sensor (SP) as well as the communication portion (TX) are powered by the energy harvesting portion (RX), •whereby information indicative of the measurement provided by the pressure sensor (SP) and data indicative of the measurement provided by said further sensor (SF) is communicated via said communication portion (TX) towards an extracorporeal receiving entity (ECE), •whereby said communication portion (TX) and/or said pressure sensor (SP) and/or said further sensor (SF) are adap

Abstract: The invention is directed to a novel method for measuring contraction characteristics of engineered heart tissue constructs (16) which is based on the mechanical coupling of the construct (16) to a support element (8) which comprises or is mechanically coupled to a piezoelectric element (10). An apparatus (1) for carrying out the method of the invention is also provided.

Abstract: The invention relates to using oligosaccharides as stimulators of plant growth in already germinated plants and methods for obtaining said oligosaccharides. The invention particularly relates to using oligosaccharides comprising N-acetyl glucosamine and glucosamine as stimulators of plant growth in already germinated plants, where the percentage of N-acetyl glucosamine in said oligosaccharides is 100% and the length of said oligosaccharides is between 1 and 6 monosaccharides. The invention particularly relates to methods for obtaining said oligosaccharides, comprising: (a) resuspending chitin with a percentage of N-acetyl glucosamine of between 85% and 100% in water, (b) heating the resulting composition to a temperature between 120 and 180° C. for a duration between 20 and 40 minutes and leaving to cool to room temperature, and (c) sonicating the resulting composition at a power between 50 and 60 Hz for a duration between 5 and 120 minutes at a temperature between 20 and 25° C.

Abstract: The present invention relates to a lidar measurement system for the detection of the presence and/or motion of particles and/or objects in a space region remote from the lidar measurement system and comprising an interferometer arrangement, as well as to a corresponding method using such a measurement system. The interferometer arrangement comprises a continuous wave laser source (2), a photodetector arrangement (7), and optical components which are adapted to split light (23) emitted by the continuous wave laser source (2), to guide it along a first optical path constituting a measurement branch (4) and along a second optical path, which is separate from the first optical path and constitutes a reference branch (5), and to eventually have it incident in a spatially coherently superimposed manner onto the photodetector arrangement (7).

Abstract: Control device (100) controlling a drilling operation and methods by which the dynamics of the continuum in question can be divided into superimposed waves, of which the wave traveling in the direction of the actuator and/or drive (10) is compensated by the actuator. This prevents reflection of the energy on the actuator. By using two sensors (30, 40) the wave traveling towards the actuator (10) and the wave traveling away from the actuator (10) can be calculated separately from one another, so that both the parameters of the wave traveling toward the actuator and the parameters of the wave traveling away from the actuator can be determined in order to be able to perform a control of the driving device of the drill string (20) on this basis.

Abstract: The present invention is directed to a method for preparing an expression vector encoding a tailored recombinase, wherein said tailored recombinase recombines asymmetric target sites within the LTR of proviral DNA of a retrovirus inserted into the genome of a host cell and is useful as means for excising the provirus from the genome of the host cell. The present invention further relates to an in vitro-method of optimising the treatment of a retroviral infection of a subject and to the use of tailored recombinases for the preparation of pharmaceutical compositions for reducing the viral load in a subjected infected by a retrovirus.

Abstract: The process according to the invention for the microbial production of a specific product and methane comprises the following steps: a) the production in a bioreactor (2, 10) of a specific product from a specific substrate using a specific organism, the producer, wherein during the production of this product metabolites such as e.g. low-molecular alcohols, aldehydes and acids, hydrogen and CO2, which may inhibit the production of the product, are obtained; and b) the production of methane by means of a methanogen, wherein in the production of the methane at least one metabolite is decomposed and by this means removed from the bioreactor (2, 10) and its energy is made usable.

Abstract: A method for milling long fibre reinforced composite plastics having at least one unidirectional top layer using a rotating milling tool, wherein work piece and tool are moved in an advancing movement parallel to the work piece cutting face relative to each other, and wherein there is an edge fibre separation angle on the work piece of 0°??edge?90°, and the blade of the tool mills the component edge in synchronization.

Abstract: The process according to the invention for the microbial production of a specific product and methane comprises the following steps: a) the production in a bioreactor (2, 10) of a specific product from a specific substrate using a specific organism, the producer, wherein during the production of this product metabolites such as e.g. low-molecular alcohols, aldehydes and acids, hydrogen and CO2, which may inhibit the production of the product, are obtained; and b) the production of methane by means of a methanogen, wherein in the production of the methane at least one metabolite is decomposed and by this means removed from the bioreactor (2, 10) and its energy is made usable.

Abstract: The invention relates to a method for producing a sandwich panel, comprising the steps: providing an upper cover layer, providing a lower cover layer, providing an intermediate layer disposed between the upper and lower cover layers, compacting the upper and lower cover layers; foaming the intermediate layer, with no foaming of the intermediate layer occurring when compacting of the upper and lower cover layers begins.

Abstract: The invention relates to a piezoelectric movement device, in particular a motor, with a piezoelectric apparatus, which has a middle area and two end areas, and with a movement body, which is mounted on or in a mount or the piezoelectric apparatus, wherein one end area is designed or both end areas are designed to exert a force in the direction of the movement body, in particular diagonally and axially or transversely of the axis to a longitudinal axis of the piezoelectric apparatus, on the movement body. The invention is characterized in that the middle area is a piezoelectric body and the end areas each comprise at least two piezoelectric bodies, which are connected with each other, in particular via contact surfaces.