Abstract: The present invention concerns reagents for the reversible protection of biological molecules. It relates in particular to compounds derived from azaisatoic anhydride and their uses for the protection of biological molecules, particularly enzymes, in order to block their activity. The invention also relates to the biological molecules protected in this manner and to the methods for making use of these reagents.

Abstract: Computer-implemented process on an image of a biological sample The present invention relates to a computer-implemented process to automatically analyze a digital image (103) of abiological sample (101). The process involves a change (203) from a first color space to a second color space. Then, fits are performed taking into account several dimensions of the second color space to classify pixels.

Abstract: The present invention relates to a compound of formula (I) below: in which: R1 represents, in particular, an alkylene group comprising from 1 to 6 carbon atoms; R2 and R3 are, in particular, H; n is 0, 1, 2 or 3; and R4 is chosen from the group consisting of: NO2, ORa, SRa and NRaRb, wherein Ra and Rb are as defined above; R5 and R6, identical or different, represent an alkyl or alkoxy group comprising from 1 to 6 carbon atoms; and R7, R8 and R9, identical or different, represent an alkyl group comprising from 2 to 6 carbon atoms.

Abstract: A field of thermal treatment of ceramic materials is provided, and relates to a method for thermal treatment of a solid ceramic part in a microwave cavity, the direction of the electrical field E being substantially uniform in an empty cavity, comprising the steps that consist of placing, in the cavity, at least one ceramic part surrounded by at least one first susceptor with dimensions, material and arrangement configured to emit infrared radiation, each first susceptor including at least one first main surface, each first main surface being an adjusted surface in which the cone distances are parallel to the electrical field E, and of emitting the microwaves into the cavity.

Abstract: The present invention concerns reagents for the reversible protection of biological molecules. It relates in particular to compounds derived from azaisatoic anhydride and their uses for the protection of biological molecules, particularly enzymes, in order to block their activity. The invention also relates to the biological molecules protected in this manner and to the methods for making use of these reagents.

Abstract: The present application relates to novel mixed compounds based on oxides and sulfides, and the use thereof as a solid electrolyte, with improved sulfide stability. The application further relates to electrochemical elements and lithium batteries containing such electrolytes.

Abstract: The method for determining a quality factor of an accelerating superconducting cavity of a particle accelerator, in particular a linear particle accelerator, the method includes determining a heat load to which a cryomodule having the accelerating cavity and a bath of cryogenic fluid is subjected, then determining a quality factor based on the determination of the heat load during the operation of the particle accelerator.

Abstract: The present invention relates to a method for the preparation of a colloidal aqueous suspension of stable zeolite nanocrystals having framework structures comprising at least one cation selected from Gd, Fe, Cu and Ce, said structures being loaded with a gas selected from O2, CO2 and mixtures thereof, to the colloidal aqueous suspension of zeolite nanocrystals obtained by such a process, and to the use of said suspension in therapy, more particularly in cancer therapy and hypoxia-related diseases and/or in diagnosis.

Abstract: An active laser medium for emitting a light beam by laser effect includes an X—F2-doped crystal, wherein X is a chemical element from the alkaline-earth family and F is fluorine. The crystal is doped with trivalent ions including: a first category of optically active dopant ions, in which each dopant ion is an ion of a first rare earth; and a second category of optically inactive dopant ions, referred to as buffer ions, in which each dopant ion is an ion of a rare earth different from the first rare earth. The second category of dopant ions has at least ions of a second rare earth and ions of a third rare earth, different from one another. The invention provides an active laser medium that can be used to obtain both a desired emission spectrum shape and a high thermal conductivity.

Abstract: The invention concerns derivatives of m-guaiacol, their preparation and their uses as biocides, in particular as antibacterials or disinfectants.

Abstract: The present disclosure relates to the identification of a biomarker, consisting in a circulating miRNA, suitable for use in the diagnosis and prognosis of high-grade serous ovarian carcinoma (HGSOC), and to diagnostic kits for use in such diagnosis.

Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of systemic mastocytosis. The inventors showed the effect of KPT-251 treatment on SCF-dependent human Mast cell (MC) line without KIT mutation (WT ROSA) and on two factor-independent MC lines with KIT mutations : ROSA ? 417-419 insY and ROSA D816V. KPT is a Selective Inhibitor of Nuclear Export (SINE) that specifically inhibits the activity of the exportin-1 (XPO1). KPT-251 treatment induces minimal toxicity in non-cancerous hematopoietic cells both in vitro and in vivo. In particular, the present invention relates a method of treating systemic mastocytosis in patient in need thereof comprising administering to the patient a therapeutically effective amount of a XPO1 inhibitor.

Abstract: Bambuterol for the Treatment of Alzheimer's Disease Bambuterol or the pharmaceutically acceptable salt thereof is used in an effective amount to treat Alzheimer's disease. The compound is administered intranasal, or through oral or intravenous routes and under an appropriate formulation for getting around the blood brain barrier, wherein it may do one more of preventing, slowing the progression of, or reversing Alzheimer's disease.

Abstract: The method for determining a quality factor of an accelerating superconducting cavity of a particle accelerator, in particular a linear particle accelerator, the method includes determining a heat load to which a cryomodule having the accelerating cavity and a bath of cryogenic fluid is subjected, then determining a quality factor based on the determination of the heat load during the operation of the particle accelerator.

Abstract: The present invention concerns reagents for the reversible protection of biological molecules. It relates in particular to compounds derived from azaisatoic anhydride and their uses for the protection of biological molecules, particularly enzymes, in order to block their activity. The invention also relates to the biological molecules protected in this manner and to the methods for making use of these reagents.

Abstract: The present invention relates to an anti-NMDA antibody or fragment or derivative thereof which is effective in inhibiting the deleterious effects of tissue-type plasminogen activator (t-PA) mediated by N-methyl-D-aspartate (NMDA) receptors and to medical uses, in particular for the treatment of neurological or neurodegenerative disorders, e.g. multiple sclerosis.