Abstract: A method for preparing a biomaterial containing at least one bioactive molecule from a base biomaterial, comprising the following successive operations carried out on the base biomaterial: a) application of a solid mixture of: cyclodextrin(s) and/or cyclodextrin derivative(s) and/or cyclodextrin inclusion complex(es) and/or cyclodextrin derivative inclusion complex(es), at least one poly(carboxylic) acid, and optionally a catalyst; b) heating at a temperature between 100° C. and 200° C. for a period of 1 to 60 minutes; c) washing with water; d) drying, wherein at least one bioactive agent is incorporated in the biomaterial by impregnation of the biomaterial after the drying step in a concentrated solution of the bioactive agent.

Abstract: The invention relates to a cell for testing geomaterials on cylindrical specimens, of rock, ground or materials manufactured on sampling sites, including at least one piston for subjecting a specimen to a stress directed along the longitudinal axis of the specimen. According to the invention, the cell has, in addition, means for shearing the specimen, capable of cracking the specimen while it is being compressed in said at least one piston.

Abstract: During a measurement in KFM mode of the surface potential of a material (P), a detection point (1) is arranged above a surface (S) of the material. Two piezoelectric actuators (2, 5) are used to monitor a mean distance of the detection point relative to the surface of the material and a mechanical oscillation of said point. During the measurement, a control voltage is applied between control electrodes (2a, 2b) of the piezoelectric actuator (2) which is dedicated to the mechanical oscillation of the detection point (1), said control voltage not having an alternative component to an angular frequency of electrical energization of said detection point. A result of the KFM measurement is therefore separate from operating parameters such as a projection angle used to perform closed-loop control and a value of the angular frequency of electrical energization. The invention thus provides absolute measurements of surface potentials.

Abstract: Novel peptides having antimicrobial activity, and compositions containing the same.

Abstract: The invention substantially relates to an imaging system for the chemical, biological or biochemical analysis of a sample (10), comprising a device (40) for holding the sample (10), a device (20) for optical detection, a lighting device (30), liable to emit a monochromatic light beam, and a wide aperture objective (f1), It is substantially characterized in that the objective (f1) is configured for, downstream of the sample (10): focusing the excitation light beam reflected at a point (C) located in the focal plane (FF) of said objective (f1), and transforming the retransmitted or scattered light beam into a quasi-parallel beam, and in that the system further comprises a device (70) for selectively blocking the collected light beam by said objective (f1).

Abstract: The process for the synthesis of a silica monolith comprises the following steps: hydrolysis of a silicon alkoxide in order to form a hydrolysis precursor followed by a condensation of said hydrolysis precursor in the presence of an organic solvent, in the presence of water and of a basic catalyst in order to form oligomeric clusters containing several silicon atoms; dispersion of said oligomeric clusters in a solution in order to form a sol; polymerization of the sol in order to obtain a gel via a first heat treatment, at a temperature below the boiling point of the constituents of the sol; drying of the gel via a second heat treatment; conversion of the gel to a xerogel via a third heat treatment; dehydration and densification of the xerogel until the silica monolith is obtained via a fourth heat treatment.

Abstract: The invention relates to a triaxial cell for testing geomaterials on specimens. The triaxial cell has at least one piston for subjecting a specimen to stress directed along the longitudinal axis of the specimen. Hydraulic means are provided for subjecting the lateral wall of the specimen to a stress, under the pressure of a fluid. The cell has at least one sealed test chamber-in which the specimen is placed, and a circuit for the controlled pressurization of said test chamber with a fluid, called the pressurizing fluid, and for the controlled draining of said fluid therefrom. The cell has mechanisms for subjecting the specimen to a tensile force, which are configured for removably fastening it between two attachments intended to move apart or closer together under the action of the piston so as to subject said specimen to longitudinal stress or on the contrary to remove the load therefrom.

Abstract: A ProNGF inhibitor for preparing a drug, said drug being in particular useful for blocking remote dissemination and cell invasion in patients suffering from cancer, in particular breast, thyroid or lung cancer.

Abstract: The microstructured optical fibre comprises a core (4) surrounded by a sheath (1) comprising a base material having a refraction index (ni) and a plurality of at least two different types of inclusion: a first type of inclusion (2) having a refraction index n2 (n2>n1), and a second type of inclusion (3) having a refraction index n3 (n3<n1). The inclusions (2, 3) are arranged and dimensioned in such a way as to ensure guidance, by total internal reflection (RTI), of a fundamental mode of the light, centred on a wavelength ?RTI, and of a fundamental mode of the light in the first photonic forbidden band (BG1), centred on a wavelength ?BG1, which is different to that ?RTI of the fundamental mode guided by total internal reflection (RTI).

Abstract: The present invention relates to novel peptides having antimicrobial activity, and compositions containing the same.

Abstract: The invention relates to a process for improving the adhesion of carbon fibres with regard to an organic matrix forming a composite material with these fibres, this composite material being obtained by bringing the fibres into contact with a resin which can be cured by chain polymerization and then polymerizing the resin, which process is characterized in that it comprises the grafting, to the surface of the fibres, before they are brought into contact with the resin, of groups capable of acting as chain transfer agents during the polymerization of said resin. Fields of application: aeronautical, aerospatial, railway, ship building and automobile industries but also the armaments industry, the industry of sports and leisure articles, and the like.

Abstract: During a measurement in KFM mode of the surface potential of a material (P), a detection point (1) is arranged above a surface (S) of the material. Two piezoelectric actuators (2, 5) are used to monitor a mean distance of the detection point relative to the surface of the material and a mechanical oscillation of said point. During the measurement, a control voltage is applied between control electrodes (2a, 2b) of the piezoelectric actuator (2) which is dedicated to the mechanical oscillation of the detection point (1), said control voltage not having an alternative component to an angular frequency of electrical energisation of said detection point. A result of the KFM measurement is therefore separate from operating parameters such as a projection angle used to perform closed-loop control and a value of the angular frequency of electrical energisation. The invention thus provides absolute measurements of surface potentials.

Abstract: The invention concerns an electrospray source having a structure comprising at least one flat and thin tip (3) in cantilever in relation to the rest (1) of the structure, the tip (3) being provided with a capillary slot (5) formed through the complete thickness of the tip and which ends up at the end (6) of the tip (3) to form an ejection orifice of the electrospray source, the source comprising means of supplying (4) the capillary slot (5) with liquid to be nebulised and means of applying an electrospray voltage to the liquid. The invention further concerns a method of manufacturing said electrospray source.

Abstract: The invention relates to a process that makes it possible to improve the mechanical strength of bonds between substrates when these bonds are produced by means of an adhesive that comprises a resin that can be cured by chain polymerization, and in particular a resin that can be cured under the effect of ionizing or light radiation. This process is characterized in that it comprises the grafting of groups capable of acting as chain transfer agents during the polymerization of said resin to the surface of the substrates, before the latter are brought into contact with the adhesive. Applications: assembling of structural, engine, passenger compartment or bodywork parts in the aeronautical, space, railway, ship-building and automotive industries.

Abstract: The invention concerns a method for determining at least one target molecule map in a tissue section, using at least one (A-X)n-B conjugate, wherein A is a tag molecule of known molecular weight, X is a linker that is cleaved during sample desorption/ionization, n is an integer of at least 1, and B is a binding molecule that binds specifically to said target molecule. When using MALDI mass spectrometry, said linker molecule X may be cleaved by photodissociation during sample laser irradiation if photocleavable at the wavelength of said MALDI laser. Alternatively, when using UV-MALDI, IR-MALDI, SIMS or DESI mass spectrometry, said linker molecule X may be cleaved by fragmentation during sample desorption/ionization.

Abstract: A method for preventing a break out of a neurodegenerative disease in an individual and for treating an individual suffering from a neurodegenerative disease comprising the administration of an effective amount of an antimicrobial and neurotrophic peptide.

Abstract: The radiometric thermometer includes a microwave sensor and electronic means for processing the electrical signal delivered by the sensor. The electronic means includes means for preamplifying the electrical signal delivered by the microwave sensor; variable-gain amplification means with automatic gain control, which means amplify the signal delivered by the preamplification means, the amplification means having an automatic gain control signal that allows the gain to be automatically adjusted on the basis of the signal output by the amplification means, and electronic temperature measurement means for measuring temperature on the basis of the automatic gain control signal.

Abstract: The invention concerns improved methods for studying peptides/proteins expression in a tissue section or for determining at least one compound, in particular a protein, expression map in a tissue section, using ionic MALDI matrices.

Abstract: The present invention relates to a process for fabricating microchannels on a substrate and to a substrate comprising these microchannels, the invention being especially applicable to the fabrication of microstructured substrates for microelectronic, microfluidic and/or micromechanical systems. The process includes a step (a) of producing at least one or at least two patterns 2 on the surface of a bottom layer 1 and a step (b) of depositing, on top of the bottom layer and the pattern or patterns, a layer 3 of polymer material obtained by polymerizing an organic or organometallic monomer that contains siloxane functional groups, for example tetramethyldisiloxane, in a plasma-enhanced, optionally remote plasma-enhanced, chemical vapor deposition reactor (PECVD or optionally RPECVD) reactor.

Abstract: Apparatus for treating age-related macular degeneration, the apparatus comprising a light source which, in operation, serves to emit a therapeutic light beam presenting an emission wavelength lying in the range 1.2 ?m to 1.3 ?m, and preferably equal to 1.26 ?m to 1.27 ?m. The laser source preferably comprises an optical fiber Raman laser.