Abstract: The invention relates to a polymer comprising at least one polymeric chain of a first type, the said chain comprising at least two blocks, the same or different, the said blocks comprising repeat units derived from the polymerisation of styrene monomers, the said units comprising at least one phenyl pendant group carrying at least one —SO3R group, R possibly being a hydrogen atom, an alkyl group or cationic counter-ion, the said two blocks being separated by a spacer group, the spacer group is a perfluorocarbon group.

Abstract: The invention relates to a static converter connected between an electrical voltage source (4) and an electrical load (6), said converter including a main static conversion arm (16) comprising an output electronic switching cell and a backup conversion arm (18) having identical structures. The static converter includes a pair of fuses (70, 72) connected on either side of the main arm (16), and a switching circuit (26) comprising a connection element (80) connecting the backup arm (18) to the connection points between the fuses and the input terminals of the main arm, such that, when a fault occurs on one of the switching cells forming the main arm (16), a stable conductive link is established between the two fuses (70, 72), the main arm (16) is isolated by the two fuses (70, 72), and the backup arm (18) is spontaneously connected to the output of the main arm (18) via the conductive line and replaces the main arm.

Abstract: The present invention concerns a method for treating and/or preventing a disease in a subject comprising the step of administrating an effective amount of a compound of formula I to a subject in need thereof.

Abstract: The invention relates to a method for functionalizing natural fatty substances: According to said method, plant oils including at least two unsaturations and the derivatives thereof, fatty acids including at least one unsaturated compound and the derivatives thereof, and mixtures of same, are reacted with a thiol derivative of formula (I), at a temperature of between 0° C. and the temperature of total degradation of the natural fatty substance and in the presence of a thermal initiator compound or a redox initiator, or by UV radiation, or by UV radiation and in the presence of a photoinitiator. The invention also relates to the resulting functionalized fatty substances and to the use thereof for the preparation of polymers. The invention further relates to a method for preparing polymers from at least one functionalized fatty substance obtained by said functionalization method.

Abstract: A control device implantable in a human body—includes a control unit and at least one electrode, said control unit being connected to each electrode to control stimulation and/or measurement thereof. The control unit includes: a timing dock; a memory storing configuration data defined to enable configuration of each electrode correlated with identifiers; a memory storing program data describing a time profile correlated with identifiers; an executor activatable to send each electrode electric pulses corresponding to a predetermined program according to a predetermined electrode configuration, according to the clock; a sequencer arranged to receive an ordered plurality of pairs, each including an electrode configuration identifier and a program identifier, and selectively to activate the executor with the electrode and program configuration pairs denoted by the pairs of identifiers received as an input, according to the order thereof and the clock.

Abstract: The invention relates to compounds of formula (I) wherein the groups A and B represent independently from each other —CH?CH—, or —C?C—, the terms t, u, v, w represent, independently from each other, values ranging from 0 to 9, the groups Y1 and Y2 can represent independently from each other an alkyl group (linear, branched or substituted) carrying from 1 to 9 carbon atoms, the groups Z1, Z2, Z3, and Z4 can represent independently from each other a chemically reactive group W, such as OH, NH2, SH, the groups Z5 and Z6 represent independently from each other a hydrogen atom, silica nanoparticles functionalized by these compounds, and their use as drugs.

Abstract: The present invention provides a chimeric polypeptide comprising a plurality of polypeptide domains that are capable of being secreted in combination with membrane vesicles and in particular exosomes. The invention also concerns the use of polypeptides of the invention and polynucleotides coding for these polypeptides, for the production of immunogenic compositions based on exosomes or DNA, to screen protein interactions. The present invention also concerns exploiting the properties of exosomes comprising a polypeptide of the invention and immunogenic compositions of the invention in immunology. The present invention concerns the use of exosomes comprising a polypeptide of the invention as a diagnostic tool.

Abstract: The use of metal-accumulating plants for implementing chemical reactions.

Abstract: A method for preparing a formaldehyde-free phenolic plastic resin, includes a step of preparing a hardener via careful oxidation of a polyol and a step of reacting the hardener with phenolic compounds.

Abstract: A device for measuring the activity of a liquid in a complex medium and an associated method, the device comprising a sealed enclosure in which the complex medium is intended to be placed and means for maintaining this enclosure at a constant temperature T, characterized in that it comprises: a means (14) for modifying the total volume of the enclosure; a pressure sensor (22) for measuring the total pressure in the enclosure; and means (24) for calculating the activity of the liquid in the complex medium from the temperature T, from the total volume of the enclosure and from the total pressure in the enclosure.

Abstract: A peptide including the amino acids sequence X9CGYX13X14AX16X17X18MX20X21X22X23X24X25X26X27CPLCX32X33, a nucleic acid coding for the peptide, and/or a recombinant vector including the nucleic acid for the preparation of a drug intended for the treatment of cancer.

Abstract: The invention relates to a method for measuring the pressure and/or molar mass of a gas in a housing, the measure being carried out via an acoustic sensor, said acoustic sensor at least one transducer (5), an electric system (8) connected to the transducer (5) and a coupling layer (6) for coupling the transducer (5) to the housing (1), said method comprising the following steps: generating using the transducer (5) an excitation acoustic signal that vibrates the housing (1) and the gas (2) in a wide frequency band; detecting with the transducer (5) a response acoustic signal characteristic of the vibrations of the housing and the gas; analysing the response electric signals from the transducer (5) using the system (8); and deriving, essentially based on the gas (2) resonance frequencies, the speed of the acoustic waves in the gas, the molar mass of the gas and the pressure thereof. The invention also relates to an assembly for implementing the method.

Abstract: The invention relates to conjugates of products of interest and of compounds targeting the cation-independent mannose 6-phosphate receptor with a high affinity. The invention also relates to their applications, for instance in enzyme replacement therapies.

Abstract: Method for the preparation of a composite electrode and accumulator or battery including at least one composite electrode, the method includes a step of pouring a medium including at least one ionic liquid, a lithium, sodium or magnesium salt with at least one inorganic molecular precursor or a polymerizable monomer, the medium being in excess, and an in situ polycondensation or polymerization step.

Abstract: The invention relates to processes for coating a surface with a crosslinked polyelectrolytes multilayer film incorporating a protein, preferably a growth factor type protein. The invention also relates to crosslinked polyelectrolytes multilayer films obtained by this process, and a coated surface obtained therefrom.

Abstract: The present invention concerns a chimeric polypeptide comprising several polypeptide domains, which is capable of being secreted in association with membrane vesicles and in particular exosomes. The present invention also concerns a polypeptide constituted by one of said domains for the secretion of a peptide or polypeptide of interest in association with membrane vesicles and in particular exosomes. The invention also concerns the use of polypeptides of the invention and of polynucleotides coding for said polypeptides for the production of immunogenic compositions based on exosomes or based on DNA or for screening protein interactions.

Abstract: The disclosure relates to a method for growing an element III nitride, wherein the growth is carried out on a substrate made of a material capable of maintaining the same crystalline structure from the element III nitride growth temperature to room temperature, the substrate being an M-V—O4 alloy, where M denotes a transition metal or a Group III element, and where V denotes N, P, S, or Sb, or an (Si-IV)O2 alloy, where IV denotes a Group IV element other than silicon. The disclosure also relates to the structures and components obtained after the implementation of the method.

Abstract: The present invention relates to a compound of one of the formulas I to XXI; a pharmaceutical composition comprising at least one such compound; and the use of at least one such compound in preparing a drug to treat, in a subject, a genetic disease resulting from at least one splicing anomaly.

Abstract: The invention concerns a process for preparing a block or comb copolymer comprising at least one hydrophilic portion and at least two hydrophobic portions, by anionic solvent-free polymerization of a prepolymer selected from a polyethylene glycol and a polyvinyl alcohol, and of a lactone or dilactone monomer. The process is carried out in the presence of an alkaline-earth metal hydride, in an inert atmosphere, and the polymerization step is not carried out under vacuum. The invention also concerns copolymers obtained by this process.

Abstract: The present invention is directed to a method for the in vitro preparation of cardiovascular progenitors cells from mammalian embryonic stem cells (ES cells) or mammalian embryonic-like state cells, preferably from primate, wherein said method comprises the use of the CD15 (SSEAI) marker as a positive cardiovascular progenitors differentiation marker. The present invention also claimed the use of a receptor tyrosine kinase inhibitor, particularly the SU5402 or SU11248 in association with the BMP2 for improving the efficiency of the desired differentiation. The present invention is also directed to the use of platelet lysate as foetal animal serum substitute in a culture medium intended to the proliferation or propagation of primate ES cells maintaining their pluripotency feature. Derived compositions or kits in relation with the claimed methods or product obtainable by the claimed methods form also part of the present invention.