Patents Assigned to University of Bath
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Publication number: 20100173977Abstract: The present invention relates to a crystal. In particular the present invention relates to a crystal of the N-domain of ACE protein. The present invention also relates to methods, processes, domain specific modulators, pharmaceutical compositions and uses of the N-domain crystal and the structure co-ordinates thereof.Type: ApplicationFiled: January 10, 2007Publication date: July 8, 2010Applicants: University of Bath, University of Cape TownInventors: Ravi Acharya, Edward David Sturrock
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Publication number: 20100160180Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of the ACE crystal and the structure co-ordinates thereof.Type: ApplicationFiled: February 26, 2010Publication date: June 24, 2010Applicants: UNIVERSITY OF BATH, University of Cape TownInventors: Ravi Acharya, Edward Sturrock
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Patent number: 7704319Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of ACE crystal and the structure coordinates thereof.Type: GrantFiled: September 12, 2003Date of Patent: April 27, 2010Assignees: University of Bath, University of Cape TownInventors: Ravi Acharya, Edward Sturrock
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Publication number: 20100010269Abstract: A reactor for carrying out a heterogeneously catalyzed reaction includes at least first and second reaction zones that are arranged in series and that each include catalytic material, heat transfer zones that are located between said serially arranged reaction zones, and a pulse-generating device, which is arranged to deliver pulses to liquid in the reactor. The reactor allows three-phase reactions to be carried out efficiently and can reduce the impact of deposited reaction by-products on reaction efficiency.Type: ApplicationFiled: October 5, 2007Publication date: January 14, 2010Applicant: The University of BathInventor: Stanislaw Tadeusz Kolaczkowski
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Publication number: 20090304269Abstract: A method of creating a viewable image comprises applying a colour vector or matrix comprising colour values and a coverage value to a material represented as a projective transformation matrix including a further coverage value. The method further comprises rendering the transformed illumination vector or matrix as an image vector or matrix.Type: ApplicationFiled: August 23, 2007Publication date: December 10, 2009Applicant: University of Bath Research and Innovation ServicesInventor: Philip Willis
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Publication number: 20090142822Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of ACE crystal and the structure coordinates thereof.Type: ApplicationFiled: July 14, 2008Publication date: June 4, 2009Applicants: UNIVERSITY OF BATH, UNIVERSITY OF CAPE TOWNInventors: RAVI ACHARYA, EDWARD DAVID STURROCK
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Patent number: 7268275Abstract: TcdB2, a protein from Photorhabdus luminescens W-14, and nucleotide sequences encoding TcdB2, are useful for enhancing expression of orally active Photorhabdus luminescens insecticidal toxins in heterologous organisms.Type: GrantFiled: November 12, 2003Date of Patent: September 11, 2007Assignee: University of BathInventors: Richard H. ffrench-Constant, Nicholas R. Waterfield
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Publication number: 20070106393Abstract: A method of fabricating a bone substitute material comprises the steps of providing a foam material (3) having an open cell structure, distorting the shape of the foam material (3) and holding the material in a distorted shape, coating the walls of the cells of the foam material with a ceramic slip (5), removing the foam material, and sintering the ceramic slip to form a bone substitute material that is approximately a positive image of the distorted foam material (3). In another method, a granular bone material is formed from a multiplicity of pieces of foam that are not distorted.Type: ApplicationFiled: August 12, 2004Publication date: May 10, 2007Applicant: UNIVERSITY OF BATHInventors: Anthony Miles, Irene Turner, Jonathan Gittings
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Publication number: 20060174816Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of the ACE crystal and the structure co-ordinates thereof.Type: ApplicationFiled: September 12, 2003Publication date: August 10, 2006Applicant: UNIVERSITY OF BATHInventors: Ravi Acharya, Edward Sturrock
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Publication number: 20040120938Abstract: A formulation for use as a bactericidal agent in the human or animal digestive system includes xanthine oxidoreductase. The formulation may especially be in the form of a formula feed formulation or enteral feed formulation for administration to a human or animal. The formulation is capable of functioning as a “natural antibiotic” to prevent or reduce bacterial infection within the gut, especially the neonatal gut.Type: ApplicationFiled: December 10, 2003Publication date: June 24, 2004Applicant: The University of BathInventors: David Russell Blake, Clifford Robert Stevens, Robert Eisenthal, Roger Harrison, Timothy Marc Miller, Rachel Edwards
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Publication number: 20040093642Abstract: A method for controlling endosperm size and development in plants. The method employs nucleic acid constructs encoding proteins involved in genomic imprinting, in the production of transgenic plants. The nucleic acid constructs can be used in the production of transgenic plants to affect interspecific hybridisation.Type: ApplicationFiled: November 6, 2003Publication date: May 13, 2004Applicant: University of Bath, a Great Britain corporationInventor: Roderick John Scott
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Patent number: 6682732Abstract: A composition for use in the treatment of lesions of the human or animal body comprises xanthine oxidoreductase and a pharmaceutically acceptable electron donor system. The composition can accelerate wound healing, especially in a hypoxic environment.Type: GrantFiled: May 3, 2001Date of Patent: January 27, 2004Assignee: The University of BathInventors: David Russell Blake, Clifford Robert Stevens, Robert Eisenthal, Roger Harrison, Timothy Mark Millar, Tulin Bodamyali, Janos Kanczler
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Patent number: 6639129Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.Type: GrantFiled: March 26, 2001Date of Patent: October 28, 2003Assignees: Wisconsin Alumni Research Foundation, University of BathInventors: Richard H. ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
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Patent number: 6556719Abstract: A method of image compression includes significance switching of DCT coefficients in block-based embedded DCT procedures. Bitwise digitized DCT coefficients are passed through successive significance sweeps of the whole image from the most significant down to the least significant coefficient bit planes. With each new sweep, newly significant coefficients may appear within a block, and block-masking is used to transmit the addresses of those newly significant coefficients. An off-mask may also be used. The invention further relates to a hardware or software-based image encoder.Type: GrantFiled: August 17, 1999Date of Patent: April 29, 2003Assignee: University of BathInventor: Donald Martin Monro
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Patent number: 6078619Abstract: An object-oriented video system is implemented as a two layer object model in a software-only video compressor. Quadtree decomposition on an error metric between the input and transmitted images directs the coder towards a foreground layer of active image fragments. A rate buffering system limits the bandwidth by transmitting only the foreground blocks which most improve the image and are above some error threshold. A high fidelity background layer is identified and communicated to the decoder, which can be used to redraw background fragments as foreground objects move across them. Blocks can be coded by various methods, such as fractal transforms or truncated DCTs. The system can be implemented in RISC processors without the need for dedicated hardware. It is suitable for low bit rate applications with slowly varying backgrounds, such as personal video communications over packet networks, or closed circuit TV surveillance.Type: GrantFiled: March 10, 1999Date of Patent: June 20, 2000Assignee: University of BathInventors: Donald Martin Monro, Jeremy Andrew Nicholls
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Patent number: 5796257Abstract: A system for detecting a fault in a power line (1) includes, in the power line (1), a first circuit (4) capable of attenuating signals within a first frequency band, which is centered on a first frequency, substantially more than it attenuates signals outside the first frequency band, and, a second circuit (5) connected to the power line (1) on one side of the first circuit (4), the second circuit (5) being capable of extracting signals within a second frequency band that includes the first frequency. The relative levels of two signals extracted by the second circuit (5), are detected and signalled, the two signals being at respective frequencies which the first circuit is capable of attenuating by different relative amounts.Type: GrantFiled: June 10, 1997Date of Patent: August 18, 1998Assignee: The University of BathInventor: Allan Thomas Johns
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Patent number: 5516788Abstract: The invention concerns compounds and their enantiomers of the formula IA or IB ##STR1## and pharmaceutically acceptable salts thereof wherein each of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11 and R.sup.12 is independently selected from hydrogen or an alkyl group containing 1-6 carbon atoms and R.sup.5 is an alkoxy group containing 1-6 carbon atoms. The invention further concerns pharmaceutical compositions comprising the active compounds and methods employing the compounds for the treatment of conditions associated with free radical formation.Type: GrantFiled: January 6, 1995Date of Patent: May 14, 1996Assignees: University of Bath, University of Cincinnati, School of MedicineInventors: Malcolm Sainsbury, Howard G. Shertzer
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Patent number: 5290331Abstract: A localized clean air system for operating theaters and a method of supplying clean air to a localized region in such situations. A fan is connected to a delivery head, which has an outlet for directing inlet clean air to the localized region in a particular pattern. A streamlined body is positioned in the outlet so that, in use, the clean air flows around the body and is modified thereby to form, immediately downstream of the body, an inner region of low velocity air encircled by an outer region of higher velocity air. Preferably, the streamlined body is symmetrical about its axis and is aligned with the clean air flow, for instance by being centrally positioned in the air outlet. The streamlined body preferably comprises a rounded head and a tapered tail. A diffuser is disposed in the clean air flow upstream of the streamlined body to minimize turbulence in the air flow.Type: GrantFiled: November 5, 1991Date of Patent: March 1, 1994Assignee: University of BathInventors: Anthony W. Miles, Norman J. Wood, Guy A. Wilson, Stephen C. Wilcox
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Patent number: 5185360Abstract: Compounds of the formula ##STR1## wherein R is hydrogen or a lower alkyl group, R.sup.1 and R.sup.2 are independently selected from hydrogen or a lower alkyl group, R.sup.3, R.sup.4 and R.sup.6 are independently selected from hydrogen, halogen or a lower alkyl group,R.sup.5 is hydrogen, hydroxy, halogen, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH.sub.2 or NR.sup.11 COR.sup.12,R.sup.7, R.sup.8, R.sup.9 and R.sup.10 are independently selected from hydrogen, hydroxy, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH.sub.2 or NR.sup.11 COR.sup.12,R.sup.11 is a hydrogen or a lower alkyl group,R.sup.12 is a lower alkyl group,with the proviso that when R is hydrogen then at least one of the substituents R.sup.1 to R.sup.10 is not hydrogen, or a salt thereof, are useful as antioxidants, within the medical and non-medical field, and that when R is hydrogen, methyl or neopentyl in formula IA, then at least one of R.sup.1 to R.sup.Type: GrantFiled: June 3, 1991Date of Patent: February 9, 1993Assignees: University of Bath, University of CincinnatiInventors: Malcolm Sainsbury, Howard G. Shertzer
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Patent number: 5017122Abstract: An apparatus for carrying out a process for the manufacture of a moulded product by compression of a powder or granules in a die, wherein a powdered die lubricant is used, lubricant particles are electrically charged and the charged particles are fed to the die in advance of the moulding powder is provided. The apparatus includes a first feed for feeding a powdered lubricant to the die, a second feed for feeding powder to the die after the powdered lubricant, and means for maintaining the electrical potential of the die at a predetermined value different from that of the powdered lubricant.Type: GrantFiled: May 22, 1989Date of Patent: May 21, 1991Assignee: University of BathInventor: John N. Staniforth