Patents Assigned to University of Delhi, Department of Chemistry
  • plant extract and method of preparation thereof
    Patent number: 8481087
    Abstract: The present invention provides Withania somnifera plant extract and composition comprising the extract useful for the treatment of neurodegenerative disease and/or disorders such as Alzheimers disease (AD). The present invention further provides a process for preparation of the extract.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: July 9, 2013
    Assignees: National Brain Research Centre, Indian Institute of Science, Molecular Biophysics Unit, University of Delhi, Department of Chemistry
    Inventors: Vijayalaksmi Ravindranath, Alok Gupta, Neha Sehgal, Subhash Chand Jain, Suman Thakur, Pankaj Khanna
  • Process of entrapping genetic materials in ultra-low size nanoparticles of inorganic compounds to form non-viral carriers
    Patent number: 6555376
    Abstract: The present invention relates to a process of entrapping genetic materials in nanoparticles of inorganic metal salts of size below 100 nm diameter to form non-viral carriers for delivery of genes. The process comprises the steps of dissolving surfactants and a cosurfactant in oil to obtain reverse micelles. An aqueous solution of genetic material is added to the reverse micelles. Thereafter the reverse micelles are divided into two equal parts. To one part, aqueous solution of inorganic metal salts is dissolved to obtain optically clear and transparent reverse micelles. To the second part aqueous solution of precipitating agent is added to obtain optically clear and transparent reverse micelles. The two equally divided parts of reverse micelles are mixed to form inorganic nanopartcles encapsulating added genetic material. Thereafter, the nanoparticles are separated from reverse micelles, the inorganic nanoparticles are dispersed in water and dialyzed to remove free metal salts, surfactant and oil.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: April 29, 2003
    Assignee: University of Delhi, Department of Chemistry
    Inventors: Amarnath Maitra, Subho Mozumdar, Susmita Mitra, Indrajit Roy