Patents Assigned to University of Exeter
  • Publication number: 20240032533
    Abstract: The invention relates to trialkyl sulfonium salts, compositions comprising the trialkyl sulfonium salts, agricultural compositions comprising such compositions, to the use of the trialkyl sulfonium salts and of the compositions as pesticide, preferably as fungicide, and to methods for controlling or combating pests and/or improving plant health by means of the trialkyl sulfonium salts and the compositions.
    Type: Application
    Filed: October 1, 2021
    Publication date: February 1, 2024
    Applicants: HELM AG, UNIVERSITY OF EXETER
    Inventors: Winfried NESS, Henrique RAMINHOS, Joerg STROOT, Johann Christian NIENDORF, Gero STEINBERG, Sarah GURR
  • Publication number: 20230413811
    Abstract: The invention relates to a trialkyl sulfonium chloride, compositions comprising the trialkyl sulfonium chloride, agricultural compositions comprising such compositions and trialkyl sulfonium chloride, respectively, to the use of the trialkyl sulfonium chloride and of the compositions as a pesticide, preferably as a fungicide, and to methods for controlling or combating pests and/or improving plant health by means of the trialkyl sulfonium chloride and compositions.
    Type: Application
    Filed: October 1, 2021
    Publication date: December 28, 2023
    Applicants: HELM AG, UNIVERSITY OF EXETER
    Inventors: Winfried NESS, Henrique RAMINHOS, Joerg STROOT, Johann Christian NIENDORF, Gero STEINBERG, Sarah GURR
  • Publication number: 20230332659
    Abstract: An elastomeric isolator is described comprising a layer of an elastomeric material, wherein the layer of elastomeric material is provided with a reinforcing material layer in the form of a graphene layer.
    Type: Application
    Filed: February 26, 2021
    Publication date: October 19, 2023
    Applicant: UNIVERSITY OF EXETER
    Inventors: Maria Rosaria MARSICO, Julián Mauricio Londono MONSALVE, Monica F. CRACIUN
  • Patent number: 11684266
    Abstract: A probe comprising a body portion and a tip portion. The body portion comprises: a first mounting portion comprising a plurality of first carriers, each first carrier being arranged to support an elongate first waveguide, the first carriers being disposed in an equiangular arrangement around a longitudinal axis of the body portion; a plurality of first waveguides, each first waveguide being supported in a respective one of the plurality of first carriers; and a body end fitting at which first ends of the first waveguides are supported in the equiangular arrangement around the longitudinal axis of the body portion such that the first waveguides can transmit electromagnetic radiation signals from an energy source to the body end fitting and/or transmit electromagnetic radiation signals from the body end fitting to a receiver.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: June 27, 2023
    Assignees: The University of Bristol, The University of Exeter, Gloucestershire Hospitals NHS Foundation Trust
    Inventors: Nicholas Stone, John Charles Clifford Day
  • Patent number: 11567389
    Abstract: A display is described which comprises a plurality of pixels (12), wherein each pixel (12) comprises a plasmonic resonator (26) including first and second metallic material elements (16, 22) and incorporating a layer (18) of a phase change material, the plasmonic resonator (26) being arranged such that in one material state of the phase change material (18) the electric field coupling between the second metallic material element (22) and the phase change material layer (18) is strong and so strong absorption of selected wavelengths of the incident light occurs, whereas in another state of the phase change material (18) the electric field coupling between the metallic material elements (16, 22) and the phase change material layer (18), and between the first and second metallic material elements (16, 22) is weak and so re-radiation of incident light occurs, the pixel (12) being of high reflectance.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: January 31, 2023
    Assignee: University of Exeter
    Inventors: Santiago Garcia-Cuevas Carrillo, Christopher David Wright
  • Patent number: 11556312
    Abstract: A co-processor for performing a matrix multiplication of an input matrix with a data matrix in one step may be provided. The co-processor receives input signals for the input matrix as optical signals. A plurality of photonic memory elements is arranged at crossing points of an optical waveguide crossbar array. The plurality of memory elements is configured to store values of the data matrix. Input signals are connected to input lines of the optical waveguide crossbar array. Output lines of the optical waveguide crossbar array represent a dot-product between a respective column of the optical waveguide crossbar array and the received input signals, and values of elements of the input matrix to be multiplied with the data matrix correspond to light intensities received at input lines of the respective photonic memory elements. Additionally, different wavelengths are used for each column of the input matrix optical signals.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: January 17, 2023
    Assignees: International Business Machines Corporation, Oxford University Innovation Limited, University of Exeter, University of Muenster
    Inventors: Abu Sebastian, Manuel Le Gallo-Bourdeau, Christopher David Wright, Nathan Youngblood, Harish Bhaskaran, Xuan Li, Wolfram Pernice, Johannes Feldmann
  • Patent number: 11414379
    Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: August 16, 2022
    Assignees: UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH OF HIGHER EDUCATION, XIAMAN UNIVERSITY, UNIVERSITY OF EXETER
    Inventors: Dandan Sun, Xianming Deng, Jinwei Zhang, Mohammad Iqbal Hossain Bhuiyan, Bradley J. Molyneaux
  • Publication number: 20220174950
    Abstract: The invention provides an antifungal composition comprising an antifungal compound of formula R—S+(R?)2 or R—N+(R?)3 wherein R is C17-C32 straight chain or branched alkyl; and each R? is independently methyl, ethyl, propyl, isopropyl or butyl; and uses of said composition as antifungal agents.
    Type: Application
    Filed: March 18, 2020
    Publication date: June 9, 2022
    Applicant: University of Exeter
    Inventors: Gero Steinberg, Sarah Gurr, Mark Wood
  • Patent number: 11339093
    Abstract: A reinforced concrete material is described comprising a cementitious material (22) in which graphene is substantially uniformly distributed. A method of production of concrete is also described comprising the steps of forming a substantially uniform suspension (20) of graphene with water, and mixing the suspension (20) with a cementitious material (22) to form a concrete material (28).
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: May 24, 2022
    Assignee: UNIVERSITY OF EXETER
    Inventors: Monica Craciun, Dimitar Dimov, Saverio Russo
  • Publication number: 20220146426
    Abstract: A test apparatus is disclosed that has a housing containing a location at which a sample tray containing a plurality of sample wells can be located, a light box positioned to permit irradiation of the sample tray, and an imaging arrangement to permit imaging of the sample tray. The light box has a light source including a light guide in the form of a plate of a transparent material and a plurality of light emitting devices provided adjacent at least one edge of the plate where a surface of the plate is provided with a plurality of transmitting regions and light is transmitted from the plate.
    Type: Application
    Filed: February 12, 2020
    Publication date: May 12, 2022
    Applicant: UNIVERSITY OF EXETER
    Inventors: Robert BEARDMORE, Ivana BEARDMORE, Kai LONGSHAW, Carlos REDING
  • Patent number: 11142568
    Abstract: The invention relates to antibodies to Aspergillus species and to methods of producing those antibodies. The invention also relates to the use of such antibodies in identifying the presence of the Aspergillus species and to methods of treating an infection with the Aspergillus species.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: October 12, 2021
    Assignee: THE UNIVERSITY OF EXETER
    Inventor: Christopher Thornton
  • Patent number: 10995061
    Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: May 4, 2021
    Assignees: United States Government as Represented by the Department of Veterans Affairs, The University of Pittsburgh—of the Commonwealth of Higher Education, Xiamen University, University of Exeter
    Inventors: Dandan Sun, Xianming Deng, Jinwei Zhang, Mohammad Iqbal Hossain Bhuiyan, Bradley J. Molyneaux
  • Patent number: 10610163
    Abstract: Assessing Susceptibility to Epilepsy and Epileptic Seizures A method and system adapted to assist with assessing susceptibility to epilepsy and/or epileptic seizures in a patient receives (202) patient brain data and generates (204) a network model from the received patient brain data. The system further generates (206) synthetic brain activity data in at least some of the nodes of the network model and computes (208) seizure frequency from the synthetic brain activity data by monitoring transitions from non-seizure states to seizures states in at least some of the nodes over time. The system further includes a device (104, 110) configured to use the seizure frequency to compute (210) a likelihood of susceptibility to epilepsy and/or epileptic seizures in the patient, and a device (104, 110) configured to compare (212) the computed likelihood with another likelihood of susceptibility to epilepsy and/or epileptic seizures in order to assess whether the likelihood has increased or decreased.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: April 7, 2020
    Assignees: UNIVERSITY OF EXETER, KINGS COLLEGE LONDON
    Inventors: John Robert Terry, Mark Richardson, Oscar Benjamin
  • Patent number: 10422947
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: September 24, 2019
    Assignees: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
  • Publication number: 20190227224
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Application
    Filed: October 19, 2018
    Publication date: July 25, 2019
    Applicants: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna AIZENBERG, Mathias KOLLE, Peter VUKUSIC, Robert D. HOWE
  • Patent number: 10231985
    Abstract: The present invention relates to the field of medicine. It more particularly relates to the use of compounds for preventing and/or treating dyslipidemia in a subject, said dyslipidemia typically being linked to the excess presence in the biological membranes, including in the biological membranes of non-adipocyte cells, of fatty acids, in particular of saturated long-chain fatty acids, and/or of sterols. The invention also relates to compositions, in particular pharmaceutical compositions and food supplements or complements, comprising such compounds, and to the uses thereof for preventing and/or treating dyslipidemia. The compounds and compositions according to the invention can in particular be advantageously used for preventing and/or treating a pathological condition selected from metabolic syndrome and/or a symptom or abnormality characteristic of metabolic syndrome, preferably for preventing or treating type 2 diabetes mellitus or hepatic steatosis.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: March 19, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE POITIERS, UNIVERSITY OF EXETER
    Inventors: Miroslava Spanova, Thierry Ferreira, Romain Clement, Shalinee Dhayal, Noël Morgan
  • Patent number: 10174086
    Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: January 8, 2019
    Assignee: University of Exeter
    Inventors: Richard W. Titball, Sergio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
  • Patent number: 10149907
    Abstract: The invention relates to a combination comprising (i) a compound A comprising a mitochondrial targeting group linked to a group capable of releasing hydrogen sulfide or a pharmaceutically acceptable salt thereof or a prodrug thereof, an inhibitor of the thioredoxin antioxidant system or a pharmaceutically acceptable salt thereof or a prodrug thereof, and/or a nitroxide or a pharmaceutically acceptable salt thereof or a prodrug thereof; and (ii) a photosensitizer or photosensitizer precursor; for use in photodynamic therapy.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: December 11, 2018
    Assignee: University of Exeter
    Inventors: Mark Elliott Wood, Paul Graham Winyard, Daniel Colin Jeremy Ferguson, Matthew Whiteman, Alison Curnow, Alexis Perry
  • Patent number: 10146007
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: December 4, 2018
    Assignees: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
  • Patent number: 10132780
    Abstract: Device and method for detecting a defect in a workpiece with a broadband transducer (10), a driving circuit connected to the transducer to operate the transducer in a actuator mode, a signal output circuit connectable to operate in a sensor mode, a control for selectively connecting the transducer to the driving circuit or signal output circuit wherein the driving circuit includes at least a pair of oscillators for generating signals of at least frequencies F1 and F2 and a summer for summing the signals to provide a driving circuit for the transducer.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: November 20, 2018
    Assignee: UNIVERSITY OF EXETER
    Inventor: Peter Robert Armitage