Abstract: A system for secure testing and provisioning of an integrated circuit (IC) includes, in part, a secure reconfigurable key provisioning architecture (SLEEVE) module disposed in the IC, and a secure asset provisioning hardware entity (SAPHE) module. The IC may include, in part, a modified IEEE 1500 wrapper to control its operation modes. The SLEEVE module may include, in part, an encoding/decoding module and an unlocking module. The encoding/decoding module may include, in part, a decode key stream cipher module, an encode key stream cipher module, Seed Key programmable linear-feedback shift registers (LFSRs), Initialization Vector (IV) LFSRs, and configuration registers. The encoding/decoding module may be configured to generate key bits for decoding and encoding inputs and outputs of the IC. The unlocking module may include, in part, a pattern matching block and a counter. The unlocking module may be configured to enable write access to the configuration registers.

Abstract: Various embodiments of the present disclosure provide for accelerated segmentation for reverse engineering of integrated circuits. In one example, an embodiment provides for receiving an SEM image for an integrated circuit, performing filtering and binarization with respect to the SEM image, extracting information associated with filter sizes for the filtering, extracting signatures related to a distribution for background pixels and foreground pixels of the SEM image, extracting respective distance to mean signatures for the background pixels and the foreground pixels, and segmenting the SEM image based at least in part on the filter sizes and the respective distance to mean signatures to generate a segmented image for the integrated circuit.

Abstract: Provided herein are compositions comprising nicotine, or a salt thereof, and pilocarpine, or a salt thereof, useful for reducing the use of betel quid and/or achieving betel quid cessation (e.g., replacement therapy). Also provided herein are methods of using the compositions in reducing the risk of developing or reducing the progression of a disease (e.g., cancer, oral disease, neurological disease, or painful condition). Compositions of the present invention may be administered to a subject with an addiction, e.g., a betel quid addiction, areca nut addiction, and/or nicotine addiction.

Abstract: Apparatus, systems, and methods described herein relate generally to autonomous mobile units carrying a modular configurable battery system that may attach and power mobile units in transportation systems. A method can include determining charge levels, current positions, and transport speeds for an electric vehicle (EV), identifying one or more EVs in need of charging, and mobilizing a Mobile Charging Station (MoCS) to deliver one or more external batteries. A processor, with a memory including computer program code, can be configured to receive current charge level data for mobile battery-powered entities, identify one or more EVs to be charged and the proximity of both MoCS and physical battery stations, and send charging instructions to the EVs. A routing and charge transaction scheduling algorithm can be used to optimize the route of one or more battery-powered entities and to schedule charge transactions between the EV and MoCS and/or the battery station.

Abstract: Embodiments provide for predicting rowhammer attack vulnerability of one or more memory cells of a direct random access memory (DRAM) chip, the DRAM chip including a plurality of memory cells. An example method, determines, for each memory cell of a subset of memory cells of the plurality of memory cells, a leakage time t, a resistance of intrinsic leakage RL based at least in part on the leakage time t, an activation time of an adjacent aggressor row to flip a bit in the memory cell, a resistance of coupling leaking RSW based at least in part on the activation time, and a toggling count. The method identifies, based at least in part on one or more of the RSW, RL, or toggling count, whether the direct random memory access (DRAM) chip is vulnerable to a rowhammer attack.

Abstract: Provided are embodiments of para-substituted 1,1-dialkyl-4-phenylpiperazin-1-ium iodides advantageous for modulating inflammation that have been synthesized and their electrophysiology activities for ?9, ?9?10, and ?7 nAChRs compared. The para position contained alkyl or aryl amides, or heterocyclic isosteres for the amide, and the alkyl groups were varied at the ammonium piperazine nitrogen to see if compensatory changes in size at this position of the molecule impacted function. The compounds were characterized with two-electrode voltage-clamp measurements on Xenopus oocytes expressing nAChRs. General, the compounds were more potent for ?9-containing receptors than for ?7, and the majority were either full or strong partial agonists for ?9-containing nAChR.

Abstract: The present disclosure provides wireless power transfer systems and methods. One such system includes a transmitter comprising a transmitter coil coupled to a power source and a transmitter metasurface slab positioned on a front side of the transmitter coil that is configured to amplify and focus a magnetic field generated by the transmitter coil towards a receiver in a non-contact manner. In such a system, the receiver comprises a receiver coil coupled to a load and a receiver metasurface slab positioned on a front side of the receiver coil configured to amplify and focus a magnetic field generated by the transmitter coil towards the receiver coil in a non-contact manner. Other systems and methods are also provided.

Abstract: The present disclosure relates to compositions and methods for the treatment of TECPR2-associated diseases or disorders. Several embodiments provided for herein relate to virally-mediated transfer of a gene to target cells to induce expression of an encoded polypeptide, protein or other product in order to ameliorate one or more symptoms of a TECPR2-associated disease or disorder in a subject. In several embodiments, the disclosed methods and compositions relate to recombinant adeno-associated virus particles encoding human TECPR2 in order to treat TECPR2-associated diseases or disorders, including spastic paraplegic type 49 (SPG49) and/or hereditary sensory and autonomic neuropathy 9 (HSAN9).

Abstract: Disclosed herein is a bioreactor system that allows perfusive flow through a porous support medium enabling 3D growth of biological samples. In some embodiments, the system comprises a sample well filled with a three-dimensional (3D) cell growth medium. The system can further comprises a liquid medium reservoir fluidly connected to the sample well by a first filter material. The system can further comprises a medium collection chamber fluidly connected to the sample well by a second filter material. The system can further comprise an absorbant material that creates an osmotic pressure gradient to produce perfusive flow. In some embodiments, osmotic pressure draws fluid from the liquid medium reservoir, through the first filter material, into the sample well where it permeates the three-dimensional cell growth medium, through the second filter material, and finally into the medium collection chamber.

Abstract: The disclosure relates, in some aspects, to compositions and methods useful for production of nitrated aromatic molecules. The disclosure is based, in part, on whole cell systems expressing artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes. In some aspects, the disclosure relates to methods of producing nitrated aromatic molecules in whole cell systems having artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes.

Abstract: A method for fabricating nano-electro-mechanical tags for identification and authentication includes, in part, forming a protective layer above a substrate, forming a first conductive layer above the protective layer serving as a first electrode, forming a piezoelectric layer above the first conductive layer, forming a second conductive layer above the piezoelectric layer, patterning the second conductive layer to form a second electrode, patterning the piezoelectric layer to expose one or more portions of the first conductive layer, and forming one or more trenches that extends into a plurality layers formed above. In addition, a sacrificial layer can be formed above portions of the substrate, and the sacrificial layer can be removed by etching to release the nano-electro-mechanical tags from the substrate.

Abstract: Embodiments of the present disclosure provide for systems for removing contaminants from a leachate, methods of removing contaminants from a leachate, and the like.

Abstract: The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

Abstract: Disclosed herein is a method for forming an anti-microbial layer on an apparatus. Also disclosed is a method for improving the anti-bacterial properties of a titanium device coated with titanium-nitride (TiN). Also disclosed is a medical apparatus comprising an anti-microbial layer prepared by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: The present disclosure provides for methods and systems for separating ultrafine particulate pollutants from aqueous suspensions. The present disclosure provide for methods and systems that can reduce the amount of ultrafine particulate pollutants from aqueous solutions, for example storm water runoff, which are not readily or easily removed using current state of the art techniques. In general, methods of the present disclosure provide for removing a portion of target ultrafine particulate pollutants using magnetic nanoparticles, which form aggregates with the ultrafine particulate pollutants. After a time period a magnetic field is applied and the aggregate can be separated from the aqueous suspension. Subsequently, the aggregates can be broken down and the magnetic nanoparticles recycled or reused while the ultrafine particulate contaminants are further processed, recycled, or disposed of.

Abstract: The instant invention describes macrocyclic compounds having antiproliferation activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders.

Abstract: In one embodiment, a method comprises training at least one model based at least in part on interactions between one or more users and electronic messages sent to addresses associated with the one or more users, receiving a first electronic message sent to a first address associated with a first user, analyzing the first electronic message to generate first feature data, determining one or more characteristics of the first user to generate second feature data, inputting, to the at least one model, the first feature data and the second feature data, and receiving, as output of the at least one model, data indicating whether to output, to the first user, a warning regarding the first electronic message.

Abstract: Described herein are compositions and methods for waste-to-energy ash in engineered aggregate in road construction.

Abstract: Provided herein is a method and apparatus for venting of intravenous tubing to remove air bubbles, and more particularly, to a venting valve that allows air bubbles to escape along a venting path while not permitting fluid passage through the venting path. An example air extraction device may include: a chamber; a fluid inlet to convey fluid from intravenous tubing into the chamber; a fluid outlet to convey fluid from the chamber to intravenous tubing for supplying to a patient; a top portion of the chamber; a branch tube extending from the top portion of the chamber, where the branch tube receives air from the fluid in the chamber; and a ball received within the chamber, where the ball is configured to rise with an influx of fluid to the chamber from the fluid inlet and to seal off the branch tube from the chamber in response to the fluid level rising to the top portion of the chamber.