Patents Assigned to University of Illinois
-
Patent number: 11805715Abstract: A photoconductive switch that uses materials that support negative differential mobility, whose operation leverages the pulse compression of a charge could to generate the “on” time of the pulse in combination with the speed of light to generate the “off” time of the pulse, is described. In one example, a method of operating a photoconductive switch, which includes two electrodes and a light absorbing material positioned therebetween, includes selecting a value for one or more parameters comprising a voltage for generation of an electric field, a spot size of a laser pulse, a temporal pulse width of the laser pulse, or an intensity of the laser pulse, wherein the selected value(s) for the one or more parameters enable the switch to operate in a region where the light absorbing material exhibits negative differential mobility, and illuminating the light absorbing material with the laser pulse to generate a charge cloud within the light absorbing material.Type: GrantFiled: October 15, 2021Date of Patent: October 31, 2023Assignees: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Lars F. Voss, Adam Conway, Karen Marie Dowling, David Lawrence Hall, Shaloo Rakheja, Kexin Li
-
Patent number: 11795403Abstract: The disclosure provides various methods for separating and recovering free fatty acids crude oil containing free fatty acids using certain ion-exchange resins to reduce the amount of free fatty acids in the crude oil to 3% or less such that the resultant oil is useable in downstream chemical processes. After separation and removal of the free fatty acids form the crude oil, the ion-exchange resin is reusable in further free fatty acid separation reactions.Type: GrantFiled: May 31, 2022Date of Patent: October 24, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Vijay Singh, Ramkrishna Singh
-
Patent number: 11798434Abstract: Disclosed herein are methods of using spun synthetic fibers to model ligaments of a joint of an animal. Further disclosed are models of joints which comprise spun synthetic fibers used to model ligaments. In certain aspects, the models of joints can be used for instructional purposes, as phantom models for testing medical devices or as models for calibration of tools used in physiological and/or biomechanical measurement.Type: GrantFiled: February 4, 2021Date of Patent: October 24, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Mariana Elizabeth Kersh, Sam Walter Goldsmith, Sara Moshage, Roberto Alonso Pineda Guzman
-
Patent number: 11789453Abstract: Aspects of the subject disclosure may include, for example, obtaining video data from a single monocular camera, wherein the video data comprises a plurality of frames, wherein the camera is attached to a mobile robot that is travelling along a lane defined by a row of crops, wherein the row of crops comprises a first plant stem, and wherein the plurality of frames include a depiction of the first plant stem; obtaining robot velocity data from encoder(s), wherein the encoder(s) are attached to the robot; performing foreground extraction on each of the plurality of frames of the video data, wherein the foreground extraction results in a plurality of foreground images; and determining, based upon the plurality of foreground images and based upon the robot velocity data, an estimated width of the first plant stem. Additional embodiments are disclosed.Type: GrantFiled: August 24, 2018Date of Patent: October 17, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Girish Chowdhary, Chinmay P. Soman, Erkan Kayacan, Benjamin C. Thompson, Zhongzhong Zhang, Anwesa Choudhuri
-
Patent number: 11788088Abstract: A CRISPR/Cas system and method for editing or regulating transcription of a genome of a cell are provided, wherein the system includes a Cas endonuclease fused with one or more degron sequences and at least one activatable cognate single guide RNA harboring an inactivation sequence in a non-essential region of the cognate sgRNA, wherein said inactivation sequence comprises one or more endonuclease recognition sites of, e.g., a ribozyme.Type: GrantFiled: September 21, 2018Date of Patent: October 17, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Ryan E. Clarke, Bradley J. Merrill, Matthew S. MacDougall, Hannah M. Pennington, Brian R. Shy
-
Patent number: 11786168Abstract: The invention provides a versatile sensing platform for sensing and analysis of biofluids, particularly well-suited for sensing and analysis of sweat. Systems of the invention allows for sensitive and selective detection of a range of analytes in sweat including metabolites, electrolytes and biomarkers. Systems of the invention provide a noninvasive and accurate means for quantitative characterization of important sweat characteristics including sweat volume, sweat loss and sweat rate. Systems of the invention are compatible with materials and device geometries for important class of conformal tissue mounted electronic devices, including epidermal electronic devices.Type: GrantFiled: June 1, 2018Date of Patent: October 17, 2023Assignees: NORTHWESTERN UNIVERSITY, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: John A. Rogers, Johnathan T. Reeder, Amay J. Bandodkar, Sungbong Kim, Yurina Sekine, Jungil Choi, Tyler R. Ray, Aurelie Hourlier-Fargette, Philipp Gutruf, Kun Hyuck Lee, Milan Raj
-
Patent number: 11786543Abstract: Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly.Type: GrantFiled: July 14, 2021Date of Patent: October 17, 2023Assignee: BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Joseph Desimone, Yogen Saunthararajah
-
Patent number: 11787769Abstract: Vaccination is the most prevalent prophylactic means for controlling seasonal influenza infections. However, an effective vaccine usually takes at least 6 months to develop for the circulating strains. Therefore, new therapeutic options are needed for acute treatment of influenza infections to control this virus and prevent epidemic/pandemic situations from developing. Described herein are fast-acting, orally active acylated amino-substituted heterocyclyl compounds effective to control this virus. In one aspect, described herein is a method of treating an influenza infection in a subject comprising administering to the subject the compounds described herein.Type: GrantFiled: May 3, 2022Date of Patent: October 17, 2023Assignees: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, CHICAGO BIOSOLUTIONS, INC.Inventors: Lijun Rong, Irina Gaisina, Gregory R. Thatcher, Norton Peet
-
Publication number: 20230327027Abstract: A method of fabricating a power semiconductor device includes forming a bi layer mask on a semiconductor substrate, where the bilayer mask comprises a first dielectric layer on the semiconductor substrate and a second dielectric layer on the first dielectric layer. The first and second dielectric layers are through-etched to define an exposed portion of the semiconductor substrate. The first dielectric layer is selectively etched to form an undercut region of the bi layer mask. A crystalline semiconductor material is epitaxially grown on the exposed portion of the semiconductor substrate, and a polycrystalline semiconductor material is deposited on the second dielectric layer of the bilayer mask. After the epitaxial growth, the bilayer mask and the polycrystalline semiconductor material are removed from the semiconductor substrate, leaving behind a mesa comprising the crystalline semiconductor material on the semiconductor substrate.Type: ApplicationFiled: July 30, 2021Publication date: October 12, 2023Applicant: The Board of Trustees of the University of IllinoisInventors: Kyekyoon Kim, Palash Sarker, Frank P. Kelly
-
Patent number: 11779219Abstract: A system for providing intraoperative feedback to a user during the course of surgery. A core imaging unit provides low-coherence optical radiation coupled to a sampling device and generates optical coherence tomography (OCT) data based on combining scattered light received from the sampling device together with a reference signal. The sampling device is adapted to receive the low-coherence optical radiation from the core imaging unit and to illuminate the tissue, and to collect light scattered by the tissue and to return said light to the core imaging unit. A core software unit receives the OCT data from the core imaging unit provides real-time feedback, such as an image, to the user via an indicator.Type: GrantFiled: December 20, 2018Date of Patent: October 10, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Stephen A. Boppart, Freddy T. Nguyen, Adam M. Zysk
-
Patent number: 11774454Abstract: The present disclosure provides non-invasive methods for determining the gender of an embryo during in vitro embryo culture.Type: GrantFiled: May 12, 2023Date of Patent: October 3, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Marcello Rubessa, Matthew B. Wheeler, Andrea Ambrosi, Scott E. Denmark, Dianelys Gonzalez-Pena
-
Patent number: 11763041Abstract: A data storage device includes a nonvolatile memory device, a volatile memory device, a data encryption circuit configured to encrypt data outputted from the nonvolatile memory device, a data decryption circuit configured to decrypt encrypted data output from the data encryption circuit and configured to provide the decrypted data to the volatile memory device, and a processor configured to perform a first process that controls installation of a first in-storage program in the data storage device, a second process configured to manage a mapping table storing a relation between a logical address and a physical address of the nonvolatile memory device, and a third process configured to execute the first in-storage program.Type: GrantFiled: April 28, 2021Date of Patent: September 19, 2023Assignees: SK hynix Inc., The Board of Trustees of the University of IllinoisInventors: Jian Huang, Xiaohao Wang, Luyi Kang, Jong Ryool Kim, Hyung Jin Lim, Myeong Joon Kang, Chang Hwan Youn
-
Patent number: 11760906Abstract: A composite dry adhesive includes (a) an adhesive layer comprising a shape memory polymer and (b) a resistive heating layer comprising a shape memory polymer composite on the adhesive layer. The shape memory polymer composite includes conductive particles dispersed in a shape memory polymer matrix, where the conductive particles have a concentration sufficient to form a conductive path through the resistive heating layer.Type: GrantFiled: June 27, 2019Date of Patent: September 19, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Seok Kim, Jeffrey D. Eisenhaure
-
Patent number: 11759450Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: February 6, 2019Date of Patent: September 19, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Yunlong Lu, Lauren Gutgesell, Carlo Ivan Rosales, Yangfeng Li
-
Patent number: 11751522Abstract: A method for increasing yield or vigor of a plant is provided, which includes the selective removal of the plant's shoot apical meristem at a period between vegetative growth stage 1 and vegetative growth stage 2, or between vegetative growth stage 2 and vegetative growth stage 3.Type: GrantFiled: August 31, 2020Date of Patent: September 12, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventor: Ken N. Paige
-
Patent number: 11755922Abstract: The present disclosure provides systems and methods that can provide portable, real-time accessible DNA memories. An example DNA-based data storage system includes a loading region configured to receive a plurality of DNA-based data storage elements in a suspension fluid and a plurality of microtubes disposed in a capture/release region. The microtubes are configured to capture and release the DNA-based data storage elements. The DNA-based data storage system also includes a linearization region configured to linearize the DNA-based data storage elements and a readout region with a readout device configured to provide information indicative of the respective DNA-based data storage elements.Type: GrantFiled: October 4, 2019Date of Patent: September 12, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Olgica Milenkovic, Nagendra Athreya, Apratim Khandelwal, Jean-Pierre Leburton, Xiuling Li, Charles Schroeder, SeyedKasra Tabatabaei, Bo Li
-
Patent number: 11753501Abstract: A frontally polymerized polymeric body includes, according to a first embodiment, a deformable polymer comprising polydicyclopentadiene (pDCPD) and/or poly(5-ethylidene-2-norbornene) (pENB), where the deformable polymer has a fracture strain of at least about 0.5 mm mm?1. According to a second embodiment, the frontally polymerized polymeric body includes a first polymer comprising pDCPD and/or pENB, and a second polymer adjacent to the first polymer also comprising the pDCPD and/or the pENB. The second polymer is more or less deformable than the first polymer. Thus, the frontally polymerized polymeric body exhibits spatially varying mechanical and/or other properties.Type: GrantFiled: January 10, 2022Date of Patent: September 12, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Jeffrey S. Moore, Nancy R. Sottos, Benjamin A. Suslick, Katherine Stawiasz, Justine E. Paul
-
Patent number: 11755640Abstract: An embodiment may involve obtaining an image composed of color channels, wherein each of the color channels represents colors therein with n bits per pixel; quantizing each of the color channels to be represented by m bits per pixel; using a space-filling curve to convert each of the color channels as quantized into respective vectors; generating, for each of the respective vectors, a respective set of m arrays, wherein the m arrays for a particular vector of the respective vectors contain indices of where a fixed value selected from a range of 0 to m?1 is found in the particular vector; applying, to each of the m arrays for each of the respective vectors, differential encoding and compression of the indices therein; mapping each of the m arrays for each of the respective vectors to blocks of nucleotides; synthesizing the blocks; and storing, in a DNA-based storage medium, the blocks.Type: GrantFiled: November 23, 2020Date of Patent: September 12, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Chao Pan, S. M. Hossein Tabatabaei Yazdi, SeyedKasra Tabatabaei, Alvaro G. Hernandez, Charles M. Schroeder, Olgica Milenkovic
-
Patent number: 11752115Abstract: Described herein are PPAR? agonists, including, but not limited to, endocannabinoids that can be used for treatment of a neuropsychiatric disorder and/or symptom thereof. Also described herein are pharmaceutical formulations containing an effective amount of a PPAR? agonists, including but not limited to endocannabinoids, where the effective amount is effective for treating a neuropsychiatric disorder and/or symptom thereof. Also described herein are methods of treating a neuropsychiatric disorder and/or a symptom thereof in a subject in need thereof.Type: GrantFiled: June 21, 2018Date of Patent: September 12, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Graziano Pinna, Andrea Locci
-
Publication number: 20230279379Abstract: A method and microfluidic device for increasing the production of extracellular vesicles are provided which include the use of a cell-adhesive substrate for culturing extracellular-vesicle-producing cells, wherein the cell-adhesive substrate is a hydrogel having a Young's modulus of about 0.1 kPa to about 5 kPa and the hydrogel is functionalized with one or more cell adhesive peptides.Type: ApplicationFiled: March 6, 2023Publication date: September 7, 2023Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: STEPHEN LENZINI, JAE-WON SHIN