Abstract: Disclosed are methods for isolating endothelial progenitor cells (EPC). More particularly, the present invention discloses methods for isolating endothelial progenitor cells that exhibit self-renewal and differentiation capacity. The isolated cellular population of the present invention is useful in a wide range of clinical and research setting including inter alia, the in vitro or in vivo generation of endothelial cells and the therapeutic or prophylactic treatment of a range of conditions via the administration of these cells. Also facilitated is the isolation of endothelial progenitor cells for research purposes such as in vitro based screening systems for testing the therapeutic impact and/or toxicity of potential treatment or culture regimes to which these cells may be exposed to. The present invention also discloses methods for isolating mesenchymal stem cells, in particular mesenchymal stem cells of fetal and/or maternal origin.
Type:
Grant
Filed:
March 13, 2014
Date of Patent:
December 11, 2018
Assignee:
The University of Queensland
Inventors:
Jatin Patel, Paul Kiarash Khosrotehrani, Nicholas Maxwell Fisk
Abstract: A sensing element for use in the detection of an analyte based on a luminescent response, the sensing element comprising a luminescent triaryl amine compound provided as a coating on a substrate.
Type:
Grant
Filed:
December 2, 2017
Date of Patent:
December 11, 2018
Assignee:
THE UNIVERSITY OF QUEENSLAND
Inventors:
Paul Leslie Burn, Paul Meredith, Paul Edward Shaw
Abstract: Disclosed are electrochemical methods, apparatus, systems and kits for the detection or monitoring of proteolysis of proteinaceous matrices such as fibrin clots. The methods, apparatus, systems and kits generally include the use of voltammetric techniques to measure the changes in current that result from diffusion of an electroactive species towards an electrode on proteolysis of a proteinaceous matrix.
Abstract: A rotorcraft having a body and a propulsion system wherein the propulsion system includes a main thrust rotor and multiple control rotors, wherein the main thrust rotor is coupled to the body, whereby the main thrust rotor is driven by a main thrust drive shaft having an axis of rotation maintained in a fixed orientation to the body of the rotorcraft and wherein the multiple control rotors are arranged to control roll, pitch and yaw of the rotorcraft and are driven by respective control drive shafts offset to the axis of rotation of the main thrust drive shaft.
Abstract: Nanocrystalline compounds containing essential nutrients have been synthesized to have effective physical and chemical characteristics, including a high contact surface area/total surface area ratio that provides maximal leaf surface contact, limited mobility and improved solubility, a net positive charge, soluble salt-forming groups, and reactive surface edges for cation exchange to release nutrient cationic ions into the water film on leaf surfaces.
Type:
Grant
Filed:
March 5, 2012
Date of Patent:
November 6, 2018
Assignee:
THE UNIVERSITY OF QUEENSLAND
Inventors:
Longbin Huang, Anh Van Nguyen, Victor Rudolph, Gordon Xu
Abstract: An optical magnetometer comprising: an optical resonator having a central void; and a magnetostrictive material located in the central void such that a change in dimension of the magnetostrictive material causes a change in mechanical modes of the optical resonator. Also a method of making the optical magnetometer.
Type:
Grant
Filed:
September 19, 2014
Date of Patent:
October 30, 2018
Assignee:
THE UNIVERSITY OF QUEENSLAND
Inventors:
Stefan Forstner, Eoin Sheridan, Warwick P. Bowen
Abstract: A method of operating a computational device to process patient sounds, the method comprises the steps of: extracting features from segments of said patient sounds; and classifying the segments as cough or non-cough sounds based upon the extracted features and predetermined criteria; and presenting a diagnosis of a disease related state on a display under control of the computational device based on segments of the patient sounds classified as cough sounds.
Type:
Grant
Filed:
March 28, 2013
Date of Patent:
October 16, 2018
Assignee:
The University of Queensland
Inventors:
Udantha R. Abeyratne, Vinayak Swarnkar, Yusuf A. Amrulloh
Abstract: An autothermal reforming catalytic structure for generating hydrogen gas from liquid hydrocarbons, steam and an oxygen source. The autothermal reforming catalytic structure includes a support structure and metal particles dispersed homogenously throughout the support structure.
Type:
Grant
Filed:
April 1, 2016
Date of Patent:
October 9, 2018
Assignees:
Saudi Arabian Oil Company, The University of Queensland
Inventors:
Jorge N. Beltramini, Moses O. Adebajo, Joao Carlos Diniz Da Costa, Gao Qing Lu, Thang V. Pham, Sai P. Katikaneni
Abstract: An autothermal reforming catalytic structure for generating hydrogen gas from liquid hydrocarbons, steam and an oxygen source. The autothermal reforming catalytic structure includes a support structure and nanosized mixed metal oxide particles dispersed homogenously throughout the support structure.
Type:
Grant
Filed:
April 1, 2016
Date of Patent:
September 11, 2018
Assignees:
Saudi Arabian Oil Company, The University of Queensland
Inventors:
Jorge N. Beltramini, Moses O. Adebajo, Joao Carlos Diniz Da Costa, Gao Qing Lu, Thang V. Pham, Sai P. Katikaneni
Abstract: A biosensor comprises an amino acid sequence of an enzyme such as glucose dehydrogenase which is capable of reacting with a substrate to produce one or more electrons, wherein the enzyme has been engineered to be switchable from a catalytically inactive to a catalytically active state in response to binding a target molecule. A method of detecting a target molecule is provided wherein an enzyme such as glucose dehydrogenase reacts with a substrate to produce one or more electrons as a result of the enzyme switching from a catalytically inactive to a catalytically active state in response to binding the target molecule.
Type:
Application
Filed:
June 1, 2016
Publication date:
August 30, 2018
Applicant:
THE UNIVERSITY OF QUEENSLAND
Inventors:
Kirill ALEXANDROV, Viktor STEIN, Zhong GUO
Abstract: An autothermal reforming catalytic structure for generating hydrogen gas from liquid hydrocarbons, steam and an oxygen source. The autothermal reforming catalytic structure includes a support structure and nanosized mixed metal oxide particles dispersed homogenously throughout the support structure.
Type:
Grant
Filed:
April 1, 2016
Date of Patent:
July 31, 2018
Assignees:
Saudi Arabian Oil Company, The University of Queensland
Inventors:
Jorge N. Beltramini, Moses O. Adebajo, Joao Carlos Diniz Da Costa, Gao Qing Lu, Thang V. Pham, Sai P. Katikaneni
Abstract: The present disclosure relates to proteins that bind to CD83 and uses thereof, for example, in therapy, prophylaxis, diagnosis or prognosis.
Type:
Application
Filed:
November 9, 2017
Publication date:
July 19, 2018
Applicants:
DENDROCYTE BIOTECH PTY LTD, THE UNIVERSITY OF QUEENSLAND, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Therese Ann Seldon, David John Munster, Derek Nigel John Hart, Martina Louise Jones, Trent Phillip Munro, Stephen Michael Mahler, Yu Zhou, James D. Marks
Abstract: The invention relates, in part, to a method of producing silica vesicles including under controlled conditions to thereby heavily influence the morphology and characteristics of the vesicles. The vesicles are shown to be effective as delivery agents for chemical and biological agents. They are also shown to be useful in methods of treatment and as components of an immunogenic composition.
Abstract: A parameter quantifying deviation from Gaussianity distribution of a patient's sounds, in the form of a non-Gaussianity distribution index, may be used to assist in diagnosis of sleep dysfunction such as OSAHS. A method for diagnosing a sleeping disorder of a subject includes processing a digitized audio signal from the subject with at least one electronic processor. The processing includes estimating a parameter quantifying deviation from Gaussianity distribution of the audio signal. in the form of a non-Gaussianity Index (NGI). The NGI value is then applied to a diagnostic model. The presence of a sleeping disorder is then indicated based on the output of the diagnostic model.
Abstract: A solder alloy may include a Sn—Cu hypereutectic area having Cu in the amount of up to 7.6 weight percent, from 0.006 to 0.5 weight percent of Al, Al2O3, or a combination thereof.
Type:
Grant
Filed:
April 6, 2012
Date of Patent:
June 19, 2018
Assignees:
NIHON SUPERIOR CO., LTD., THE UNIVERSITY OF QUEENSLAND
Inventors:
Tetsuro Nishimura, Kazuhiro Nogita, Stuart David McDonald, Jonathan James Read, Tina Ventura
Abstract: Compositions and methods are for inducing, promoting or otherwise facilitating pain relief. More particularly, sub-normovasodilatory doses of nitric oxide donors are used in the therapeutic management of vertebrate animals including humans, for the prevention or alleviation of pain, especially neuropathic pain. In some applications of the method, nitric oxide donors can be administered by any suitable route so as to provide concentrations of NO that are about ½ to 10?15 times those known to induce vasodilation in normal circulations.
Abstract: A coil arrangement for use in a magnetic resonance imaging system, the imaging system being for generating a magnetic imaging field in an imaging region, the coil arrangement including at least three coils for at least one of transmitting, receiving or transceiving an electromagnetic field, each coil being provided on a coil geometry and being substantially orthogonal.
Type:
Grant
Filed:
March 30, 2010
Date of Patent:
May 22, 2018
Assignee:
The University of Queensland
Inventors:
Stuart Crozier, Adnan Trakic, Ewald Weber, Bing Keong Li, Hua Wang
Abstract: A copolymer is prepared by the polymerization of monomers that include an ultraviolet absorbing monomer, and a base-solubility-enhancing monomer. The copolymer is useful for forming a topcoat layer for electron beam and extreme ultraviolet lithographies. Also described are a layered article including the topcoat layer, and an associated method of forming an electronic device.
Type:
Grant
Filed:
August 7, 2015
Date of Patent:
May 1, 2018
Assignees:
ROHM AND HAAS ELECTRONIC MATERIALS LLC, THE UNIVERSITY OF QUEENSLAND
Inventors:
James W. Thackeray, Ke Du, Peter Trefonas, III, Idriss Blakey, Andrew Keith Whittaker
Abstract: An apparatus including an array of wells including a number of well channels, each well channel including a plurality of wells in the well channel, the wells containing a substance in use, one or more inlets for receiving respective fluids and channels coupled to the one or more inlets for selectively supplying one or more fluids to each well channel to thereby expose the substance to different conditions allowing a response of the substance to the conditions to be determined.
Type:
Grant
Filed:
September 13, 2012
Date of Patent:
April 3, 2018
Assignee:
The University of Queensland
Inventors:
Justin John Cooper-White, Drew Murray Titmarsh
Abstract: An assembly for press forming a deformable material including: a first die array including a plurality of dies, the first die array defining a first die profile; a second die array that is complementary with the first die array and including a plurality of dies, the second die array defining a second die profile that is complementary with the first die profile; and a drive for driving at least one of the first die array and the second die array; wherein in use the plurality of dies of the first die array and the plurality of dies of the second die array sequentially engage the deformable material along a processing length to deform the deformable material to a predetermined profile.