Abstract: Systems and methods for visually displaying instances of increased susceptibility for commission of medical errors are provided. Execution of programming instructions on a computer-readable medium causes a processor to retrieve historical workload data corresponding to environmental conditions experienced by and near misses associated with an individual or team of individuals during a first period of time from one or more data repositories. Retrieved workload data is processed to establish threshold limits for distinct working conditions represented within the workload data for the individual or team of individuals. Workload data corresponding to a second period of time is retrieved for the individual or team of individuals and compared to established threshold limits by the processor. Based on the comparison, the processor generates one or more displayable indicia indicative of the individual's or team of individuals' risk of committing a medical error due to an experienced workload.
Type:
Grant
Filed:
March 7, 2019
Date of Patent:
August 10, 2021
Assignee:
The University of South Alabama
Inventors:
Amy Ashe Campbell, Christopher Todd Harlan, Stephen Matthew Campbell
Abstract: A nanocomposite including an array of extended length fibers with nanofibers oriented in transverse relation to the extended length fibers. The nanofibers are mechanically interlocked with the extended length fibers using a connecting agent concentrated at contact locations between the extended length fibers and the nanofibers without saturating the composite. The resultant composite of fibers and connecting agent is characterized by significant internal porosity with an internal void volume not occupied by the connecting agent.
Abstract: The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.
Type:
Application
Filed:
March 16, 2018
Publication date:
March 26, 2020
Applicant:
University of South Alabama
Inventors:
Gary Piazza, Xi Chen, Herbert Weissbach, Shailaja Kesraju Allani
Abstract: A method and apparatus for uniformly and directionally aligning and stretching nanofibers inside a porous medium is described. The nanofibers may include nanotubes, nanowires, long-chain polymer molecules or likewise. Porous medium may include a porous layer, fabric, or composite prepreg or likewise. According to one embodiment, an apparatus for directional alignment of nanofiber in a porous medium includes a fluid matrix with nanofibers. A porous medium is provided as well as a device for forcing the fluid matrix radially through the porous medium.
Abstract: An illumination device and method including multiple illumination sources such as LEDs, lasing diodes or the like operatively connected to a multi-branch light guide adapted to collect and co-align beams from the illumination sources for delivery of high intensity, spatially uniform illumination.
Abstract: Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for detecting endometrial cancer or ovarian cancer are provided.
Type:
Grant
Filed:
May 11, 2015
Date of Patent:
November 13, 2018
Assignee:
UNIVERSITY OF SOUTH ALABAMA
Inventors:
Michael A. Finan, Rodney P. Rocconi, Lewis K. Pannell
Abstract: A method whereby nanostructures aligned within a matrix material to define an aligned admixture are transferred into a receiving porous medium while substantially maintaining the nanostructure alignment such that the nanostructures may be aligned predominantly in a common direction within receiving porous medium. Resulting composite structures are also provided.
Abstract: Disclosed are methods for treating cancer and precancerous conditions with PDE10A specific inhibitors and diagnosis of neoplastic diseases based on elevated levels of PDE10A.
Abstract: Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into target cells using the genetic delivery systems.
Type:
Application
Filed:
December 11, 2017
Publication date:
July 12, 2018
Applicant:
University of South Alabama
Inventors:
Victor Solodushko, Brian Fouty, Vira Bitko
Abstract: A method for reducing or inhibiting damage to skin is disclosed herein. In some embodiments, the damage is ultraviolet (UV) radiation-induced damage. In some embodiments, the method comprises applying to the skin prior to exposure to radiation damaging source, a formulation containing an effective amount of silver nanoparticles (AgNPs) A method for treating damaged skin, and formulations include AgNPs are also disclosed.
Abstract: A process and system for separating CO2 from a flue gas stream is disclosed. The process involves (a) contacting a flue gas stream containing water vapor and CO2 with an ionic absorbent under absorption conditions to absorb at least a portion of the CO2 from the flue gas stream and form a CO2-absorbent complex; wherein the ionic absorbent comprises a cation and an anion comprising an amine moiety; and (b) recovering a gaseous product having a reduced CO2 content.
Type:
Grant
Filed:
November 14, 2014
Date of Patent:
February 27, 2018
Assignees:
Chevron U.S.A. Inc., University of South Alabama
Inventors:
Daniel Chinn, Russell Evan Cooper, Zunqing He, James H. Davis, Jr., Kevin N. West, Hye Kyung Timken, Michael S. Driver
Abstract: Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into target cells using the genetic delivery systems.
Type:
Grant
Filed:
July 11, 2014
Date of Patent:
December 12, 2017
Assignee:
University of South Alabama
Inventors:
Victor Solodushko, Brian Fouty, Vira Bitko
Abstract: Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for ameliorating pancreatic cancer targeting the CXCR4 receptor and the CXCL12 ligand.
Abstract: The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent associated with albumin, administering a second chemotherapeutic agent; and administering a third chemotherapeutic agent.
Abstract: An aqueous ionic absorbent solution is disclosed containing (a) about 15 wt. % to about 80 wt. % of one or more diluents, based on the total weight of the aqueous ionic absorbent solution; and (b) an ionic absorbent containing a cation and an anion comprising an amine moiety.
Type:
Grant
Filed:
September 30, 2015
Date of Patent:
September 5, 2017
Assignees:
Chevron U.S.A. Inc., University of South Alabama
Inventors:
Daniel Chinn, Rusell Evan Cooper, Zunqing He, James H. Davis, Jr., Kevin N. West, Hye Kyung Timken, Michael S. Driver
Abstract: Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
Type:
Grant
Filed:
October 21, 2015
Date of Patent:
January 10, 2017
Assignee:
University of South Alabama
Inventors:
Lalita Samant, Rajeev Samant, Shamik Das, Eddie Reed
Abstract: Some embodiments of the present invention relate to agents and compositions for treating cancer. More embodiments include agents and compositions for modulating the activity of the Hedgehog pathway.
Type:
Grant
Filed:
September 20, 2012
Date of Patent:
October 11, 2016
Assignee:
University of South Alabama
Inventors:
Eddie Reed, Lalita Samant, Rajeev Samant
Abstract: Some embodiments of the present technology relate to methods and compositions for the diagnosis and treatment of cancer. Some embodiments include methods and compositions for the diagnosis and treatment of castration-resistant prostate cancer. Some embodiments include methods and compositions for the diagnosis and treatment of pancreatic cancer.
Abstract: A method for reducing or inhibiting damage to skin is disclosed herein. In some embodiments, the damage is ultraviolet (UV) radiation-induced damage. In some embodiments, the method comprises applying to the skin prior to exposure to radiation damaging source, a formulation containing an effective amount of silver nanoparticles (AgNPs) A method for treating damaged skin, and formulations include AgNPs are also disclosed.
Abstract: The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various disease and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria.
Type:
Grant
Filed:
October 20, 2014
Date of Patent:
August 2, 2016
Assignee:
University of South Alabama
Inventors:
Glenn Wilson, Susan Ledoux, Mikhail Alexeyev, Inna Shokolenko, Mark N. Gillespie