Abstract: An image is reconstructed based upon a filtered backprojection (FBP) technique using a reconstruction filter which is customized or shaped by parameters including a weight value that is determined for weighing projection data according to a predetermined noise model. The weight value is determined based upon rays or views in the projection data. A regularization term is also combined with the noise-weighted FBP.

Abstract: An in-vivo implantable coil assembly includes a planar coil having at least one coil layer formed from conductive traces disposed in or on a polymer matrix. A ferrite platelet is bonded to a surface of the polymer matrix. Methods of making and using the in-vivo implantable coil assembly are also disclosed.

Abstract: Methods are provided for estimating the risk of developing melanoma and related malignancies in an individual. Methods and compositions for diagnosing, treating, and preventing melanoma and related malignancies also are provided.

Abstract: A method of digital image enhancement and sharpening (11, 12) which may be applied to restoration of blurred digital images of arbitrary origin. The method uses a specially formulated constraint (15) to reconstruct the original images. In particular, the constraint of the present method minimizes the area where strong image parameter variations and discontinuities occur. This new constraint is called a minimum gradient support (MGS) constraint. The MGS constraint generates a stable sharp solution of the linear ill-posed image restoration equation with an arbitrary blurring operator.