Abstract: A method and device for purifying a process gas mixture, such as a cryogen gas, in which impurity components of the mixture are removed by de-sublimation via cryo-condensation. The gas mixture is cooled to a temperature well below the condensation temperature of the impurities, by direct exchange of the gas mixture with a cooling source disposed in a first region of the device. The de-sublimated or frozen impurities collect about the cooling region surfaces, and ultimately transferred to a portion of the device defining an impurities storage region. The output-purified gas is transferred from the impurities storage region, is optionally passed through a first micrometer sized filter, through a counter-flow heat exchanger, and ultimately up to an output port at room temperature. A method of purging the collected impurities and regenerating the device is also disclosed.
Type:
Grant
Filed:
September 25, 2014
Date of Patent:
July 16, 2019
Assignees:
UNIVERSITY OF ZARAGOZA, QUANTUM DESIGN INTERNATIONAL, INC., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Inventors:
Conrado Rillo Millan, Jost Diederichs, Michael Bancroft Simmonds
Abstract: The present invention relates to the therapeutic use of the carboxy-terminal domain of the heavy chain of the tetanus toxin for the treatment of amyotrophic lateral sclerosis (ALS).
Type:
Grant
Filed:
April 5, 2010
Date of Patent:
February 3, 2015
Assignees:
University of Zaragoza, Autonomous University of Barcelona
Inventors:
María Moreno Igoa, Ana Cristina Calvo Royo, Maria Jesús Muñoz Gonzalvo, Maria Pilar Zaragoza Fernández, Rosario Osta Pinzolas, José Aguilera Avila
Abstract: The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS).
Type:
Application
Filed:
April 5, 2010
Publication date:
October 14, 2010
Applicants:
UNIVERSITY OF ZARAGOZA, AUTONOMOUS UNIVERSITY OF BARCELONA
Inventors:
Maria Moreno Igoa, Ana Cristina Calvo Royo, Maria Jesús Muñoz Gonzalvo, Maria Pilar Zaragoza Fernández, Rosario Osta Pinzolas, José Aguilera Avila
Abstract: Process for the oxidation of a hydrocarbon substrate to a corresponding oxidised hydrocarbon compound by contacting the hydrocarbon substrate with an oxygen containing atmosphere in presence of a catalyst being active in the oxidation of the hydrocarbon substrate, which process comprises the steps of: passing a process gas containing the hydrocarbon substrate through a reaction zone with the catalyst; introducing the oxygen containing atmosphere divided into a plurality of substreams successively into the reaction zone; within the reaction zone reacting the process gas continuously with the oxygen containing atmosphere; and withdrawing from the reaction zone a product gas containing oxidised hydrocarbon compound and carbon monoxide.
Type:
Grant
Filed:
September 1, 2000
Date of Patent:
February 4, 2003
Assignees:
Haldor Topsoe A/S, University of Zaragoza, Du Pont Iberia, S.A.
Inventors:
Jens Perregaard, Jesus Santamaria, Miquel Menendes, Reyes Mallada, Gregory Patience, Julian R. H. Ross, Erzeng Xue, Jean-Claude Volta, Anne Julbe, David Furrusseng