Abstract: The invention described herein is a bioactive composite material comprising thin layers of bioactive glass reinforced with thin ductile metallic layers, and the use of this material in bone replacement procedures.
Type:
Grant
Filed:
September 20, 2001
Date of Patent:
June 1, 2004
Assignee:
USBiomaterials Corporation
Inventors:
John J. Mechlosky, Jr., Zheng Chen, Daniel Clupper
Abstract: Compositions and methods for treating nails and adjacent tissues are disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with therapeutic agents, hydrophilic polymers, and other optional components. The compositions optionally include an appropriate aqueous carrier for topical administration. The methods involve applying an effective nail-enhancing amount of the composition to the nails and adjacent tissues for a sufficient amount of time to cause the formation of a hydroxyapatite or other calcium phosphate mineral layer on the nail surface.
Type:
Grant
Filed:
January 19, 2000
Date of Patent:
February 11, 2003
Assignee:
USBiomaterials Corporation
Inventors:
Guy LaTorre, David C. Greenspan, Alice D. Greenspan
Abstract: This invention relates, generally, to nutritional supplements which contain bioactive glass. These supplements are useful in both veterinary and human contexts. The compositions of the subject invention can be used to achieve a number of advantageous results including: enhancing the growth rates of young animals, osteogenic stimulation, strengthening the skeletal structure, and treating osteoporosis.
Abstract: A method for treating wounds including contacting a wound with an effective wound healing amount of bioactive glass and topical antibiotic and composition for the accelerated healing of wounds and burns including particulates of bioactive glass and at least one topical antibiotic.
Abstract: This invention relates to a method for treating inflammatory symptoms such as burning, redness, itching, swelling and pain which accompany skin disorders other than wounds of the skin. The method comprising topical application of a topical medicinal composition comprising a non-interlinked, particulate bioactive glass mixed with a topical medicinal carrier to the site of the skin disorder.
Abstract: Biodegradable polymeric therapeutic substantially nonporous implant materials incorporating bioactive ceramics such as Bioglass® ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.
Abstract: The invention described herein is a bioactive composite material comprising thin layers of bioactive glass reinforced with thin ductile metallic layers, and the use of this material in bone replacement procedures.
Type:
Grant
Filed:
December 18, 1998
Date of Patent:
October 23, 2001
Assignee:
Usbiomaterials Corporation
Inventors:
Daniel Clupper, John J. Mechlosky, Jr., Zheng Chen
Abstract: Biodegradable polymeric therapeutic implant materials incorporating bioactive ceramics such as Bioglass.RTM. ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.
Abstract: A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel saliva, etc. having a particle size range <90 .mu.m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity.
Type:
Grant
Filed:
July 16, 1997
Date of Patent:
April 7, 1998
Assignees:
USBiomaterials Corporation, University of Maryland
Inventors:
Leonard J. Litkowski, Gary D. Hack, David C. Greenspan