Patents Assigned to VA BOSTON HEALTHCARE SYSTEM
  • ABCB5(+) STEM CELLS FOR TREATING OCULAR DISEASE
    Publication number: 20180064762
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Application
    Filed: October 30, 2017
    Publication date: March 8, 2018
    Applicants: VA Boston Healthcare System, Schepens Eye Research Institute, Children's Medical Center Corporation
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
  • ABCB5(+) stem cells for treating ocular disease
    Patent number: 9801912
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: October 31, 2017
    Assignees: VA Boston Healthcare System, Schepens Eye Research Institute, Children's Medical Center Corporation
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
  • WOUND HEALING AND TISSUE ENGINEERING
    Publication number: 20160106782
    Abstract: The present invention is directed to wound healing scaffolds cografted with a population of stem cells, wherein the population of stem cells are ABCB5+ stem cells. The scaffolds are, for instance, collagen glycosaminoglycan scaffolds.
    Type: Application
    Filed: May 9, 2014
    Publication date: April 21, 2016
    Applicants: Va Boston Healthcare System, The Brigham and Women's Hospital, Inc., Children's Medical Center Corporation
    Inventors: Markus H. Frank, Natasha Y. Frank, Dennis P. Orgill, George F. Murphy
  • ABCB5(+) STEM CELLS FOR TREATING OCULAR DISEASE
    Publication number: 20150374756
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 31, 2015
    Applicants: VA BOSTON HEALTHCARE SYSTEM, SCHEPENS EYE RESEARCH INSTITUTE, CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander