Abstract: One example method for improving the efficiency of robotic surgical procedures via surgical procedure data analysis. The method includes accessing surgical procedure data of a robotic surgical procedure. The surgical procedure data contains data or events associated with the robotic surgical system during the robotic surgical procedure. The method further includes accessing a procedure setup plan for the robotic surgical procedure corresponding to the surgical procedure data and determining an idle period of the surgical procedure based on the surgical procedure data. The method also includes analyzing the surgical procedure data to detect one or more events associated with the idle period to determine a cause of the idle period, and generating a recommendation for modifying the procedure setup plan for the robotic surgical procedure based on the determined cause of the idle period.

Abstract: Introduced here are retinal cameras having one or more optical components whose position can be modified so that the left and right eyes can be imaged during a single imaging operation. Collectively, the optical component(s) may be referred to as an “optical assembly.” An optical assembly can include the objective lens, lens tube, and other optical components such as mirror(s), light source(s), capturing medium(s), etc. An optical assembly of a retinal camera may be movable between a first position and a second position along an arcuate path. By moving the optical assembly between the first and second positions along the arcuate path, the retinal camera can align the lens tube with the left and right eyes of an individual while clearing her nose. Thus, the retinal camera may generate images of the left and right eyes during an imaging procedure without requiring that the individual move her head.

Abstract: Introduced here is an attachable unit that connects to a base unit through a snap-fitting mechanism. The attachable unit can include a top housing structure and a bottom housing structure that are ultrasonically welded together. The top housing structure can include the toe portion that is integral with remaining portions of the top housing structure, where the toe portion is configured to provide the snap-fit with the base unit.

Abstract: The present invention is directed to a wearable fitness and/or heart rate monitoring device which includes motion detecting sensor(s), a galvanic skin response (GSR) sensor, a user input interface, or any combination thereof. The device accounts for signal noise, produced when an individual passes thru varying exercise states, by filtering out the motion of the individual using a 3-axis accelerometer. The invention also provides for systems and methods of operating the monitor which extracts and/or stores true or correct heart rate values from the heartbeat waveform signal observed from a PPG.

Abstract: One example method for biomarker detection in digitized pathology samples includes receiving a plurality of image patches corresponding to an image of a pathology slide having a hematoxylin and eosin-stained (“H&E”) stained sample of tissue, each image patch representing a different portion of the image; for each image patch, determining, using a first trained machine learning (“ML”) model, a patch biomarker status; and determining, using a second trained ML model, a tissue sample biomarker status for the sample of tissue based on the patch biomarker statuses of the image patches.

Abstract: A user-interface for visualizing a colonoscopy procedure includes a video region and a navigational map upon which coverage annotations are displayed. A live video feed received from a colonoscope is displayed in the video region. The navigational map depicts longitudinal sections of a colon. The coverage annotations are presented on the navigation map and indicate whether one or more of the longitudinal sections is deemed adequately inspected or inadequately inspected during the colonoscopy procedure.

Abstract: Described herein is a front-end for a neural recording system that boosts input impedance of the front-end circuit. The front-end includes an amplifier and two choppers. A first input terminal of the first chopper may be coupled to a first output terminal from one or more signal sensors. A first input terminal of the second chopper may be coupled to a second output terminal from the signal sensors. A second input terminal of the first chopper may be coupled to a first output terminal of a feedback subsystem. A second input terminal of the second chopper may be coupled to a second output terminal of the feedback subsystem. The output terminals of each chopper may each be coupled to a different capacitor such that after switching, the voltage of each capacitor remains substantially the same, improving the input impedance of the circuit.

Abstract: A handheld system includes a housing, a motion-generating mechanism disposed within the housing, an attachment arm extending from the housing and having a first end coupled to the motion-generating mechanism and a second end configured to receive a user assistive device, a first sensor mounted to measure a first motion of the handheld system and generate a first signal indicative of the first motion, and a control system coupled to the motion-generating mechanism and the first sensor. The control system is configured to use the first signal to stabilize the user-assistive device and compensate for human tremors imparted to the housing.

Abstract: A finger-wearable blood pressure monitor device includes a cuff, a tactile sensor array, and control circuitry. The tactile sensor array is disposed on or adjacent to an inward facing surface of the cuff. The tactile sensor array includes a plurality of sensors. The control circuitry is coupled to the tactile sensor array and includes logic that when executed by the control circuitry causes the finger-wearable blood pressure monitoring device to perform operations. The operations include monitoring, over a first time period, a pressure applied to each of the plurality of sensors by a digital artery of a finger. The operations also include generating a plurality of tactile waveforms in response to monitoring the pressure. Each of the plurality of tactile waveforms corresponds to the pressure applied to a respective one of the plurality of sensors over the first time period. The operations further include estimating blood pressure based, at least in part, on the plurality of tactile waveforms.

Abstract: Systems and methods for segmenting surgical videos are disclosed. One example method includes receiving, by a processor of a computing device, surgical video, the surgical video comprising at least a sequence of video frames of a surgical procedure; in response to receiving an identification of a video frame, generating, by the processor, a bookmark based on the video frame; associating, by the processor, the bookmark with the video frame; and storing, by the processor, the bookmark in a non-transitory computer-readable medium.

Abstract: One example method for improving the efficiency of robotic surgical procedures by integrating applications into the surgeon console user interface is presented. The method includes generating a surgeon console user interface for displaying at a surgeon console associated with a robotic surgical device during a robotic surgical procedure. The surgeon console user interface includes a main region configured for displaying a video signal of the robotic surgical procedure, a left side region for displaying data related to the surgical tools controlled by a left hand controller; and a right side region for displaying data related to the surgical tools controlled by a right hand controller. The method further includes displaying the graphical user interface on a display device of the surgeon console and integrating applications into the surgeon console user interface in response to determining that the surgeon console switches to an application mode.

Abstract: Individual-specific changes in health conditions are detected using a latent space mapping generated from baseline physiological data collected in a longitudinal study of the individual. Historical baseline data in an n-dimensional input space is modeled into a k-dimensional latent space, where k<n. The mapping for the model is then used to convert new physiological data into a latent space point, which can be used to determine if the associated newly collected physiological data is anomalous and thus indicative of a change in health condition. Anomalies can be inferred from poor fit between the point and baseline data within the latent space, or form large error between data reconstructed into the input space from the point and the original new physiological data.

Abstract: The present disclosure is directed towards systems and methods that leverage machine-learned models to decrease the rate at which abnormal sites are missed during a gastroenterological procedure. In particular, the system and methods of the present disclosure can use machine-learning techniques to determine the coverage rate achieved during a gastroenterological procedure. Measuring the coverage rate of the gastroenterological procedure can allow medical professionals to be alerted when the coverage output is deficient and thus allow an additional coverage to be achieved and as a result increase in the detection rate for abnormal sites (e.g., adenoma, polyp, lesion, tumor, etc.) during the gastroenterological procedure.

Abstract: Described herein are techniques to ensure a user using an external device is authorized to connect and connecting to a correct implantable medical device using a wireless communication protocol. A request for authorization is sent to the external device from the implantable medical device, and the authorization can be provided by an authorization pulse sent using the implantable medical device charger over the inductive link between the charging device and the implanted device. The authorization pulse can be trusted because the inductive link is short range, ensuring the patient is aware of the connection to the implanted device. Once the implanted device receives the authorization pulse, it may finalize the pairing over the first connection.

Abstract: A technique for generating and presenting context-aware recommendations to assist a patient in managing a chronic health condition. A health management platform provides various services that are accessible to a patient via a graphical user interface (GUI). Input data are received from various services and processed to generate contextual data associated with the patient such as a health state of the patient. Using the contextual data, a recommendation to access a particular service is generated and presented to the patient via the GUI. For example, in response to determining a health state of a patient, a recommendation to access a service to improve the health state of the patient can be automatically presented via the GUI to encourage the patient to access the service.

Abstract: An imaging system includes a light source to emit a plurality of wavelengths of light, and a camera coupled to receive the light reflected back from tissue in a body. Also included are a database with reflectance data for a plurality of tissue types, and a controller coupled to the light source, the database, and the camera. The controller causes the imaging system to perform operations, including: generating image data with the camera; receiving the image data from the camera with the controller; comparing, with the controller, the image data to the reflectance data in the database; and determining a tissue type in the image data in response to comparing the image data to the reflectance data.

Abstract: One example method for improving the efficiency of robotic surgical procedures by integrating applications into the surgeon console user interface is presented. The method includes generating and displaying a first graphical user interface at a surgeon console associated with a robotic surgical device during a robotic surgical procedure, and detecting a combination of user actions through control devices of the surgeon console. The method further includes responsive to detecting the combination of the user actions, causing surgical tools of the robotic surgical device to be locked and generating and displaying a second graphical user interface at the surgeon console which includes user interfaces of applications and is configured to be interactive through the control devices. The method further includes detecting a user action to exit the application mode, causing the surgical tools to be unlocked, and updating and displaying the first graphical user interface at the surgeon console.

Abstract: The disclosure relates to systems and methods for dynamic release planning for insect release. One example method includes receiving information indicating a population of wild insects within a geographic region; determining a number of wild insects per unit area within the geographic region; placing, based on the number of wild insects per unit area, one or more insect release points based on the number of wild insects per unit area, each insect release point indicating a release of a predefined quantity of insects; and generating an insect release route through the geographic region, the insect release route passing through each insect release point.

Abstract: Systems and methods for using a prediction model jointly with a normalization model to provide prediction results are provided. One example method includes receiving an input image of a tissue sample of a patient and generating a normalized image by applying a normalization model on the input image. The normalization model is configured to generate normalized data using input data for a prediction model, and the prediction model is configured to generate prediction results using normalized data generated by the normalization model. The normalization model and the prediction model are jointly trained. The method further includes generating a prediction of disease severity for the patient by applying the prediction model on the normalized image.

Abstract: Provided herein are compositions and methods for assaying target proteins on extracellular vesicles in plasma. In some methods, the responsiveness of a subject to immunotherapy is determined.