Patents Assigned to Virginia Intellectual Property Division
  • Expression of human protein C in mammary tissue of transgenic mammals
    Patent number: 5589604
    Abstract: Recombinant protein C characterized by a high percentage of active protein can be obtained in the milk of transgenic mammals that incorporate DNAs according to the present invention. Transgenic mammals of the present invention are produced by introducing into developing embryos DNA that encodes protein C, such that the DNA is stably incorporated in the DNA of germ line cells of the mature mammals and inherited in normal, mendelian fashion.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: December 31, 1996
    Assignees: American Red Cross, Virginia Intellectual Property Division
    Inventors: William N. Drohan, Tracy D. Wilkins, William H. Velander, John L. Johnson