Patents Assigned to Visiogen, Inc.
  • Patent number: 9498326
    Abstract: Disclosed is an injector which comprises an injector housing having a longitudinal axis and an injection probe disposed along the longitudinal axis. The injector further comprises an intraocular lens disposed in the housing. The intraocular lens comprises first and second interconnected viewing elements, and the optical axes of the first and second viewing elements are substantially aligned. The optical axes are substantially orthogonal to the longitudinal axis of the housing. The injector further comprises a lens carrier which engages one of the viewing elements. The viewing elements are moveable in response to longitudinal movement of the lens carrier relative to the injector housing. The longitudinal movement causes both (i) the optical axes to be displaced relative to each other and (ii) the viewing elements to be disposed substantially on the longitudinal axis of the injector housing.
    Type: Grant
    Filed: March 6, 2012
    Date of Patent: November 22, 2016
    Assignee: Visiogen, Inc.
    Inventor: George Tsai
  • Patent number: 9421089
    Abstract: Disclosed are accommodating intraocular lenses for implantation in an eye having an optical axis. In certain embodiments, an intraocular lens includes an anterior optic, a posterior optic, and a support structure configured to move the optics relative to each other along an optical axis between an accommodated state and an unaccommodated state. In certain embodiments, at least a portion of the support structure can be modified in situ to alter reaction forces between the support structure and at least one structure of the eye. In certain embodiments, a refractive property of one of the anterior or posterior optics can be modified in situ while leaving the refractive properties of the remaining one of the anterior or posterior optics substantially unaffected. Additional embodiments and methods are also disclosed.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: August 23, 2016
    Assignee: VISIOGEN, INC.
    Inventor: Gholam-Reza Zadno-Azizi
  • Patent number: 9095426
    Abstract: Disclosed is an apparatus for compacting an intraocular lens. The apparatus comprises a lens compactor having a first configuration for retaining the intraocular lens in an unstressed condition and a second configuration in which the compactor stresses the lens into an at least partially compacted condition without advancing the lens along an injection axis of the compactor. The compactor accomplishes this by applying a compacting force in a direction generally orthogonal to the optical axis of the lens. The compactor is responsive to a compactor actuator that is movable by a user to change the compactor from the first configuration to the second configuration. Additional apparatus and methods are disclosed as well.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: August 4, 2015
    Assignee: Visiogen, Inc.
    Inventors: Ian Ayton, Scott Evans, Tuan Nguyen
  • Patent number: 9005283
    Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: April 14, 2015
    Assignee: Visiogen Inc.
    Inventors: Tuan Anh Nguyen, Gholam-Reza Zadno-Azizi, Scott Evans
  • Patent number: 8784485
    Abstract: An injector for inserting an intraocular lens into an eye includes a lumen. The lumen can include a terminal portion at a distal end and a proximal portion juxtaposed with the terminal portion. An injector plunger can be disposed within the lumen for generating a driving force on the intraocular lens. The injector can include a lens frictional force that has a first value when the lens is at a first location within the proximal portion and a second value when the lens is at a second location within the terminal portion. The first value can be smaller than the second value. In some embodiments, the lens frictional force increases abruptly from the first value to the second value as the lens approaches the distal end of the lumen.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: July 22, 2014
    Assignee: Visiogen, Inc.
    Inventors: George Tsai, Tuan Anh Nguyen, Phu Nguyen, Scott Evans
  • Patent number: 8680172
    Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: March 25, 2014
    Assignee: Visiogen, Inc.
    Inventor: Xiugao Liao
  • Patent number: 8579970
    Abstract: A telescopic intraocular lens system comprises a telescopic optical system comprising an anterior optic interconnected with a posterior optic. The optics are substantially aligned on an optical axis of the optical system. The optics are formed from a soft material and the optics are substantially immovable relative to each other along the optical axis in response to accommodative forces of the type observed in the capsular bag of the human eye.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: November 12, 2013
    Assignee: Visiogen, Inc.
    Inventors: Gholam-Reza Zadno-Azizi, Scott Evans, Luis Vargas, Valdemar Portney
  • Publication number: 20130150961
    Abstract: A method is provided for implanting an accommodating intraocular lens system in a capsular bag of an eye. The method includes providing the accommodating intraocular lens having an anterior viewing element and a posterior viewing element. The anterior viewing element has a width in a range between approximately 4.5 millimeters and approximately 6.5 millimeters. The method further includes forming an opening in an anterior portion of the capsular bag. The opening has a minimum width not less than approximately 4 millimeters and has a maximum width not greater than approximately 6.0 millimeters. The method further includes placing the accommodating intraocular lens system within the capsular bag. The capsular bag overlaps at least a portion of the anterior viewing element and defines an overlap region with a width in a range between approximately 0.1 millimeters and approximately 0.75 millimeters.
    Type: Application
    Filed: February 6, 2013
    Publication date: June 13, 2013
    Applicant: VISIOGEN, INC.
    Inventor: Visiogen, Inc.
  • Patent number: 8430928
    Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: April 30, 2013
    Assignee: Visiogen, Inc.
    Inventor: Xiugao Liao
  • Patent number: 8425595
    Abstract: An injector for inserting an intraocular lens into an eye includes a lumen. The lumen can include a terminal portion at a distal end and a proximal portion juxtaposed with the terminal portion. An injector plunger can be disposed within the lumen for generating a driving force on the intraocular lens. The injector can include a lens frictional force that has a first value when the lens is at a first location within the proximal portion and a second value when the lens is at a second location within the terminal portion. The first value can be smaller than the second value. In some embodiments, the lens frictional force increases abruptly from the first value to the second value as the lens approaches the distal end of the lumen.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: April 23, 2013
    Assignee: Visiogen, Inc.
    Inventors: George Tsai, Tuan Anh Nguyen, Phu H. Nguyen, Scott Evans
  • Patent number: 8403984
    Abstract: Disclosed are apparatus for delivering an accommodating intraocular lens to an eye. One apparatus includes an injector with a longitudinal injection passage that has a longitudinal injection axis. The apparatus also includes an accommodating intraocular lens having two interconnected viewing elements. The injector has a member for moving the lens into the injection passage of the apparatus. The accommodating intraocular lens has a longitudinal bisection axis and is initially disposed within the injector with the longitudinal bisection axis at an angle which is non-parallel and non-perpendicular to the injection axis. Additional apparatus and methods are disclosed as well.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: March 26, 2013
    Assignee: Visiogen, Inc.
    Inventors: George Tsai, Phu Nguyen
  • Patent number: 8377123
    Abstract: A method is provided for implanting an accommodating intraocular lens system in a capsular bag of an eye. The method includes providing the accommodating intraocular lens having an anterior viewing element and a posterior viewing element. The anterior viewing element has a width in a range between approximately 4.5 millimeters and approximately 6.5 millimeters. The method further includes forming an opening in an anterior portion of the capsular bag. The opening has a minimum width not less than approximately 4 millimeters and has a maximum width not greater than approximately 6.0 millimeters. The method further includes placing the accommodating intraocular lens system within the capsular bag. The capsular bag overlaps at least a portion of the anterior viewing element and defines an overlap region with a width in a range between approximately 0.1 millimeters and approximately 0.75 millimeters.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: February 19, 2013
    Assignee: Visiogen, Inc.
    Inventors: Scott Evans, Reza Zadno, Luis Vargas
  • Publication number: 20130013060
    Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.
    Type: Application
    Filed: May 24, 2012
    Publication date: January 10, 2013
    Applicant: Visiogen, Inc.
    Inventors: Gholam-Reza Zadno-Azizi, Albert C. Ting, Tuan Anh Nguyen, Valdemer Portney
  • Publication number: 20120310342
    Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.
    Type: Application
    Filed: August 17, 2012
    Publication date: December 6, 2012
    Applicant: VISIOGEN, INC.
    Inventors: Tuan Anh Nguyen, Gholam-Reza Zadno-Azizi, Scott Evans
  • Publication number: 20120245684
    Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
    Type: Application
    Filed: June 6, 2012
    Publication date: September 27, 2012
    Applicant: Visiogen, Inc.
    Inventor: Xiugao Liao
  • Patent number: 8246679
    Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: August 21, 2012
    Assignee: Visiogen, Inc.
    Inventors: Tuan Anh Nguyen, Gholam-Reza Zadno-Azizi, Scott Evans
  • Patent number: 8222360
    Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: July 17, 2012
    Assignee: Visiogen, Inc.
    Inventor: Xiugao Liao
  • Publication number: 20120165824
    Abstract: Disclosed is an injector which comprises an injector housing having a longitudinal axis and an injection probe disposed along the longitudinal axis. The injector further comprises an intraocular lens disposed in the housing. The intraocular lens comprises first and second interconnected viewing elements, and the optical axes of the first and second viewing elements are substantially aligned. The optical axes are substantially orthogonal to the longitudinal axis of the housing. The injector further comprises a lens carrier which engages one of the viewing elements. The viewing elements are moveable in response to longitudinal movement of the lens carrier relative to the injector housing. The longitudinal movement causes both (i) the optical axes to be displaced relative to each other and (ii) the viewing elements to be disposed substantially on the longitudinal axis of the injector housing.
    Type: Application
    Filed: March 6, 2012
    Publication date: June 28, 2012
    Applicant: VISIOGEN, INC.
    Inventor: George Tsai
  • Patent number: 8187325
    Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: May 29, 2012
    Assignee: Visiogen, Inc.
    Inventors: Gholam-Reza Zadno-Azizi, Tuan Anh Nguyen
  • Patent number: 8142498
    Abstract: Disclosed is an injector which comprises an injector housing having a longitudinal axis and an injection probe disposed along the longitudinal axis. The injector further comprises an intraocular lens disposed in the housing. The intraocular lens comprises first and second interconnected viewing elements, and the optical axes of the first and second viewing elements are substantially aligned. The optical axes are substantially orthogonal to the longitudinal axis of the housing. The injector further comprises a lens carrier which engages one of the viewing elements. The viewing elements are moveable in response to longitudinal movement of the lens carrier relative to the injector housing. The longitudinal movement causes both (i) the optical axes to be displaced relative to each other and (ii) the viewing elements to be disposed substantially on the longitudinal axis of the injector housing.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: March 27, 2012
    Assignee: Visiogen, Inc.
    Inventor: George Tsai