Patents Assigned to Visiopharm A/S
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Patent number: 11276165Abstract: A method and a system for training a deep learning model to obtain histopathological information from images.Type: GrantFiled: June 12, 2018Date of Patent: March 15, 2022Assignee: Visiopharm A/SInventors: Jeppe Thagaard, Johan Dore Hansen, Thomas Ebstrup, Michael Friis Lippert, Michael Grunkin
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Patent number: 10209165Abstract: The quality of staining histological specimens has an impact on the histological assessment of the specimen. One of the causes for variability in the accuracy is the variations in the staining of the specimens to be tested in the working laboratories. The present invention provides a method for assessing the staining quality in a working laboratory and providing a quantitative quality measure for the staining quality. Thereby, it is possible for each working laboratory to evaluate their staining quality and to get feedback of how to improve the quality. The invention further relates to a system and a software program for carrying out the method.Type: GrantFiled: March 9, 2015Date of Patent: February 19, 2019Assignee: Visiopharm A/SInventors: Michael Grunkin, Johan Doré Hansen
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Patent number: 9697582Abstract: Disclosed is a method and a system for obtaining and analyzing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.Type: GrantFiled: March 24, 2014Date of Patent: July 4, 2017Assignee: Visiopharm A/SInventors: Michael Grunkin, Steen T. Rasmussen, Kim A. Bjerrum, Johan Dore Hansen
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Publication number: 20140348410Abstract: Disclosed is a method and a system for obtaining and analyzing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.Type: ApplicationFiled: March 24, 2014Publication date: November 27, 2014Applicant: VISIOPHARM A/SInventors: Michael Grunkin, Steen T. Rasmussen, Kim A. Bjerrum, Johan Dore Hansen
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Patent number: 8682050Abstract: The present invention relates to a method and a system for obtaining and analysing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.Type: GrantFiled: June 21, 2012Date of Patent: March 25, 2014Assignee: Visiopharm A/SInventors: Michael Grunkin, Steen T. Rasmussen, Kim A. Bjerrum, Johan Dore Hansen
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Publication number: 20130016892Abstract: The present invention relates to a method and a system for obtaining and analysing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.Type: ApplicationFiled: June 21, 2012Publication date: January 17, 2013Applicant: Visiopharm A/SInventors: Michael Grunkin, Steen T. Rasmussen, Kim A. Bjerrum, Johan Dore Hansen
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Patent number: 8229194Abstract: The present invention relates to a method and a system for obtaining and analysing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.Type: GrantFiled: November 16, 2007Date of Patent: July 24, 2012Assignee: Visiopharm A/SInventors: Michael Grunkin, Steen T. Rasmussen, Kim A. Bjerrum, Johan Dore Hansen
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Publication number: 20110234812Abstract: The present invention relates to methods for identifying and optionally quantifying stained cells in a cell or tissue sample and determining expression level of a target, as well as methods for determining staining intensity and/or staining quality of a stained sample, calibrating digital imaging apparatus using the methods, as well as systems and a computer readable mediums therefore.Type: ApplicationFiled: August 14, 2009Publication date: September 29, 2011Applicant: Visiopharm A/SInventors: Michael Grunkin, Niels Taekker Foged
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Publication number: 20100215227Abstract: The present invention relates to a method and a system for obtaining and analysing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.Type: ApplicationFiled: November 16, 2007Publication date: August 26, 2010Applicant: Visiopharm A/SInventors: Michael Grunkin, Steen T. Rasmussen, Kim A. Bjerrum, John Dore Hansen