Patents Assigned to Vita-Invest, S.A.
  • Patent number: 7001910
    Abstract: The present invention refers to compounds of the general formula (I), to their possible pharmaceutically acceptable salts and tautomeric forms. The present invention also refers to a process for their production and to their use as antidiabetic and *hypoglycemic agents, alone or in combination with other antidiabetic agents, such as sulfonilureas or biguanides, as well as for the treatment of complications associated to the resistance to the insulin, such as hypertension, hyperuricemia or other cardiovascular, metabolic, endocrine conditions, or other conditions related with diabetes.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: February 21, 2006
    Assignee: Vita-Invest S.A.
    Inventors: Marisabel Mourelle Mancini, Juan Carlos Del Castillo Nieto, Elisabet De Ramon Amat
  • Patent number: 6894076
    Abstract: New esters derived from (RR, SS)-3-(2-dimethylaminomethyl-1-hydroxycyclohexyl)phenyl 2-hydroxybenzoate, analog to Tramadol, a process for obtaining them and the use of these compounds for the production of a medicament with analgesic properties. These new products of general formula (I) exhibit an analgesic activity higher than that of tramadol.
    Type: Grant
    Filed: December 26, 2000
    Date of Patent: May 17, 2005
    Assignee: Vita-Invest, S.A.
    Inventors: Marisabel Mourelle Mancini, Elisabet De Ramon Amat, Juan Huguet Clotet
  • Patent number: 6455585
    Abstract: New esters derived from substituted phenyl-cyclohexyl compounds, which are derived from Tramadol, process for obtaining them and their use for preparing a drug with analgesic properties. These new compounds of general formula (I) have a higher analgesic activity, a lower toxicity and a longer effective time period than Tramadol.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: September 24, 2002
    Assignee: Vita Invest, S.A.
    Inventors: Juan Carlos Del Castillo Nieto, Joan Huguet Clotet, Elisabet De Ramon Amat, Maria Chalaux Freixa, Marisabel Mourelle Mancini
  • Patent number: 5658916
    Abstract: The agent is the compound 3-{2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethy l}-2-methyl-6,7,8,9-tetrahydropyrido [1,2-a]pyrimidin-4-one having the formula (I) ##STR1## and pharmaceutically acceptable salts thereof; the process is based on the reduction of a selected pyridin salt by means of a metal borohydride; its preferred application is as an antipsychotic agent.
    Type: Grant
    Filed: October 12, 1995
    Date of Patent: August 19, 1997
    Assignee: Vita-Invest, S.A.
    Inventors: Jose Maria Caldero Ges, Joan Huguet Clotet, Francisco Marquillas Olondriz, Pere Dalmases Barjoan, Anna Bosch Rovira, Joan Roca Acin, Juan Carlos Del Castillo Nieto
  • Patent number: 5331005
    Abstract: Amidines derived from 3-aminoethyl indoles of formula (I) ##STR1## where R.sub.1 is an atom of hydrogen or a lower alkyl or alkenyl group: R.sub.2 is an atom of hydrogen or a lower alkyl or alkenyl , aryl, arylalkyl or cycloalkyl group; R.sub.3 and R.sub.4 may be the same or different and are an atom of hydrogen or a lower straight or branched chain alkyl group; and R.sub.5 is an atom of hydrogen; a straight or branched chain alkyl, alkenyl or alkynyl group, which may be substituted with an hydroxy group, alkoxy, alkoxycarbonyl, carboxyl, trifluoromethyl, halogen, carbonyl, cyano; a cyano group, phenyl, aryl, cycloalkyl, heterocycle or arylalkyl, optionally substituted with a hydroxy, alkoxy, halogen, amino, alkoxycarbonyl, carboxyl, trifluoromethyl, carbonyl, cyano, nitro, lower alkyl, lower alkenyl, or may form an optionally substituted heterocycle with R.sub.4 and with the nitrogen atom; and the physiologically acceptable salts thereof.
    Type: Grant
    Filed: July 7, 1993
    Date of Patent: July 19, 1994
    Assignee: Vita-Invest, S.A.
    Inventors: Jose M. Caldero Ges, Anna Bosch Rovira, Joan Maria Roca Acin, Pere Dalmases Barjoan, Francisco Marquillas Olondriz