Abstract: The invention described herein provides, in part, improved methods, compositions, and kits for detecting analytes in biological samples.
Type:
Grant
Filed:
December 22, 2017
Date of Patent:
June 7, 2022
Assignee:
Vital Biosciences, Inc.
Inventors:
Mounir A. Koussa, Andrew Ward, Padric Garden, Anthony Pulido, Bradley Demarco, Christopher Blanchard, ArunRichard Chandrasekaran, Joshua Forman, Lisa Caldwell
Abstract: A system may include emitters configured to emit radiation at a first wavelength of electromagnetic (EM) radiation and a second wavelength of EM radiation towards a biological tissue, and receivers configured to receive responses to the first and second wavelengths of EM radiation after the wavelengths of EM radiation interact with the biological tissue. The system may also include a signal mixer unit configured to perform operations that include replicate and mix first signals representative of the responses to the first wavelength of EM radiation received by the receivers and second signals representative of the responses to the second wavelength of EM radiation received by the receivers to generate a set of spectro-spatial responses, replicate and mix the spectro-spatial responses to generate markers, and replicate and mix the markers and user-selected markers to output a sequence associated with characterization of the biological tissue.
Type:
Grant
Filed:
September 16, 2019
Date of Patent:
April 6, 2021
Assignee:
VITAL BIOSCIENCES INC.
Inventors:
Iman Khodadad, Alexander Wong, Farnoud Kazemzadeh
Abstract: A method may include emitting a band of electromagnetic (EM) radiation towards a specimen that covers at least a first and a second wavelength of EM radiation. The method may also include receiving, at a first receiver configured to receive the first wavelength of EM radiation, responses to the EM radiation after the EM radiation interacts with the specimen; and receiving, at a second receiver configured to receive the second wavelength of EM radiation, responses to the EM radiation after the EM radiation interacts with the specimen. The method may also include extracting markers from a combination of first signals representative of the received responses at the first receiver and second signals representative of the received responses at the second receiver, the extracting including replicating and mixing the first signals and the second signals to extract the plurality of markers.
Type:
Grant
Filed:
January 15, 2019
Date of Patent:
September 1, 2020
Assignee:
VITAL BIOSCIENCES INC.
Inventors:
Iman Khodadad, Alexander Wong, Farnoud Kazemzadeh
Abstract: A system may include emitters configured to emit radiation at a first wavelength of electromagnetic (EM) radiation and a second wavelength of EM radiation towards a biological tissue, and receivers configured to receive responses to the first and second wavelengths of EM radiation after the wavelengths of EM radiation interact with the biological tissue. The system may also include a signal mixer unit configured to perform operations that include replicate and mix first signals representative of the responses to the first wavelength of EM radiation received by the receivers and second signals representative of the responses to the second wavelength of EM radiation received by the receivers to generate a set of spectro-spatial responses, replicate and mix the spectro-spatial responses to generate markers, and replicate and mix the markers and user-selected markers to output a sequence associated with characterization of the biological tissue.
Type:
Grant
Filed:
September 20, 2018
Date of Patent:
September 17, 2019
Assignee:
VITAL BIOSCIENCES INC.
Inventors:
Iman Khodadad, Alexander Wong, Farnoud Kazemzadeh