Abstract: The present invention discloses compositions and methods for enhancing the effect (e.g., duration) of a neurotoxin treatment. The compositions herein include neurotoxins and neuron growth inhibitors. Such compositions are administered locally to treat or prevent conditions, such as dermatological conditions, urological conditions, thyroid conditions, optical conditions, and neurological conditions.
Abstract: The present invention discloses compositions and methods for the prevention and treatment of skin and hair diseases, such as, for example, alopecia, psoriasis, and keloids. In one embodiment, the present invention discloses a method for preventing and treating hair loss by applying locally to a region lacking hair a p38? MAP kinase inhibitor. The p38? MAP kinase inhibitor is preferably formulated as a gel, ointment, spray or solution that can be applied topically, transdermally, or subcutaneously to the targeted region.
Abstract: Novel compositions and methods and pharmaceutical compositions for altering skin coloration. The methods include administering a cytokine to a dermal region desired to be altered. The cytokine is formulated for local administration. The cytokine is preferably administered in conjunction with a therapeutic procedure. The therapeutic procedure is preferably selected from the group consisting of excision, dermabrasion, laser therapy, cryosurgery, grafting, camouflaging, scarification, and salabrasion.
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